The risk of thromboembolism is increased in inflammatory bowel disease and its symptoms may be overlooked. Furthermore, its treatment can be complex and is not without complications. We describe a case of an adolescen...The risk of thromboembolism is increased in inflammatory bowel disease and its symptoms may be overlooked. Furthermore, its treatment can be complex and is not without complications. We describe a case of an adolescent boy who developed a cerebral sinus venous thrombosis during a relapse of his ulcerative colitis and who, while on treatment with heparin, developed heparin-induced thrombocytopenia (HIT). The treatment was then switched to fondaparinux, a synthetic and selective inhibitor of activated factor .展开更多
Objective: To investigate whether the periodic EEG patterns seen in healthy an d sick full term neonates (tracéalternant and burst suppression, respectively) have different frequency characteristics. Methods: Bur...Objective: To investigate whether the periodic EEG patterns seen in healthy an d sick full term neonates (tracéalternant and burst suppression, respectively) have different frequency characteristics. Methods: Burst episodes were selected from the EEGs of 9 healthy and 9 post asphyctic full term neonates and subject ed to power spectrum analysis. Powers in two bands were estimated; 0-4 and 4-3 0 Hz, designated low and highfrequency activity, respectively (LFA, HFA). The s pectral edge frequency (SEF) was also assessed. Results: In bursts, the LFA powe r was ower in periods of burst suppression as compared to those of tracéalterna nt. The parameter that best discriminated between the groups was the relative am ount of low and highfrequency activity. The SEF parameter had a low sensitivity to the group differences. In healthy neonates, the LFApower was higher over the posterior right as compared to the posterior left region. Conclusions: Spectral power of low frequencies differs significantly between the burst episodes of he althy and sick neonates. Significance: These results can be used when monitoring cerebral function in neonates.展开更多
文摘The risk of thromboembolism is increased in inflammatory bowel disease and its symptoms may be overlooked. Furthermore, its treatment can be complex and is not without complications. We describe a case of an adolescent boy who developed a cerebral sinus venous thrombosis during a relapse of his ulcerative colitis and who, while on treatment with heparin, developed heparin-induced thrombocytopenia (HIT). The treatment was then switched to fondaparinux, a synthetic and selective inhibitor of activated factor .
文摘Objective: To investigate whether the periodic EEG patterns seen in healthy an d sick full term neonates (tracéalternant and burst suppression, respectively) have different frequency characteristics. Methods: Burst episodes were selected from the EEGs of 9 healthy and 9 post asphyctic full term neonates and subject ed to power spectrum analysis. Powers in two bands were estimated; 0-4 and 4-3 0 Hz, designated low and highfrequency activity, respectively (LFA, HFA). The s pectral edge frequency (SEF) was also assessed. Results: In bursts, the LFA powe r was ower in periods of burst suppression as compared to those of tracéalterna nt. The parameter that best discriminated between the groups was the relative am ount of low and highfrequency activity. The SEF parameter had a low sensitivity to the group differences. In healthy neonates, the LFApower was higher over the posterior right as compared to the posterior left region. Conclusions: Spectral power of low frequencies differs significantly between the burst episodes of he althy and sick neonates. Significance: These results can be used when monitoring cerebral function in neonates.
