Flumorph （SYP-L190） is a new systemic fungicide with good protective, curative and antisporulant activities but no phytotoxicity to certain plants. Its performance on the environmental ecosystem is unknown. Tetrahym...Flumorph （SYP-L190） is a new systemic fungicide with good protective, curative and antisporulant activities but no phytotoxicity to certain plants. Its performance on the environmental ecosystem is unknown. Tetrahymena thermophila and Bacillus thuringiensis are two of biological indicators for the aquatic and soil environmental ecosystem respectively. Microcalorimetric technique based on the heat output was applied to evaluate the influence of fungicide flumorph （SYP-L190） on the two microorganisms. The thermogenic curves and corresponding thermodynamic and thermokinetic parameters were obtained. SYP-L190 at a concentration of 50-100 μg·mL^-1 had 5%- 10% inhibitory ratios aganist Tetrahymena thermophila and was used as a protection reagent, while at a concentration of 100-200 μg·mL^-1 SYP-L190 had 10%-20% inhibitory ratios and was used as a therapy reagent. The metabolic thermogenic curves of Bacillus thuringiensis contained bacterial growth phase and sporulation phase. The SYP-L190 at a concentration of 0-200 μg·mL^-1 had no influence on bacterial growth phase, but led to a little lag of the sporulation phase with a constant heat output. Hormesis was obviously observed in present study.展开更多
Light weight and mechanically strong α-chitin aerogels were fabricated using the sol-gel/self-assembly method from α-chitin in different aqueous alkali hydroxide(KOH, Na OH and Li OH)/urea solutions. All of the α-c...Light weight and mechanically strong α-chitin aerogels were fabricated using the sol-gel/self-assembly method from α-chitin in different aqueous alkali hydroxide(KOH, Na OH and Li OH)/urea solutions. All of the α-chitin solutions exhibited temperature-induced rapid gelation behavior. 13 C nuclear magnetic resonance(NMR) spectra revealed that the aqueous alkali hydroxide/urea solutions are non-derivatizing solvents for α-chitin. Fourier transform infrared(FT-IR), X-ray diffraction(XRD) and cross-polarization magic angle spinning(CP/MAS) 13 C NMR confirmed that α-chitin has a stable aggregate structure after undergoing dissolution and regeneration. Subsequently, nanostructured α-chitin aerogels were fabricated by regeneration from the chitin solutions in ethanol and then freeze-drying from t-Bu OH. These α-chitin aerogels exhibited high porosity(87% to 94%), low density(0.09 to 0.19 g/cm^3), high specific surface area(419 to 535 m^2/g) and large pore volume(2.7 to 3.8 cm^3/g). Moreover, the α-chitin aerogels exhibited good mechanical properties under compression and tension models. In vitro studies showed that m BMSCs cultured on chitin hydrogels have good biocompatibility. These nanostructured α-chitin aerogels may be useful for various applications, such as catalyst supports, carbon aerogel precursors and biomedical materials.展开更多
基金Project-supported by the National Natural Science Foundation of China（Nos. 30570015, 20472066, 20621502）, the Natural Science Foundation of Hubei Province （No. 2005ABC002） and the Science Research Foundation of Chinese Ministry of Education （No. [2006]8IRT0543）.
文摘Flumorph （SYP-L190） is a new systemic fungicide with good protective, curative and antisporulant activities but no phytotoxicity to certain plants. Its performance on the environmental ecosystem is unknown. Tetrahymena thermophila and Bacillus thuringiensis are two of biological indicators for the aquatic and soil environmental ecosystem respectively. Microcalorimetric technique based on the heat output was applied to evaluate the influence of fungicide flumorph （SYP-L190） on the two microorganisms. The thermogenic curves and corresponding thermodynamic and thermokinetic parameters were obtained. SYP-L190 at a concentration of 50-100 μg·mL^-1 had 5%- 10% inhibitory ratios aganist Tetrahymena thermophila and was used as a protection reagent, while at a concentration of 100-200 μg·mL^-1 SYP-L190 had 10%-20% inhibitory ratios and was used as a therapy reagent. The metabolic thermogenic curves of Bacillus thuringiensis contained bacterial growth phase and sporulation phase. The SYP-L190 at a concentration of 0-200 μg·mL^-1 had no influence on bacterial growth phase, but led to a little lag of the sporulation phase with a constant heat output. Hormesis was obviously observed in present study.
基金supported by the National Natural Science Foundation of China (21422405, 51373125)the Major Program of National Natural Science Foundation of China (21334005)+1 种基金the facility support of the Natural Science Foundation of Hubei Provincethe Fundamental Research Funds for the Central Universities
文摘Light weight and mechanically strong α-chitin aerogels were fabricated using the sol-gel/self-assembly method from α-chitin in different aqueous alkali hydroxide(KOH, Na OH and Li OH)/urea solutions. All of the α-chitin solutions exhibited temperature-induced rapid gelation behavior. 13 C nuclear magnetic resonance(NMR) spectra revealed that the aqueous alkali hydroxide/urea solutions are non-derivatizing solvents for α-chitin. Fourier transform infrared(FT-IR), X-ray diffraction(XRD) and cross-polarization magic angle spinning(CP/MAS) 13 C NMR confirmed that α-chitin has a stable aggregate structure after undergoing dissolution and regeneration. Subsequently, nanostructured α-chitin aerogels were fabricated by regeneration from the chitin solutions in ethanol and then freeze-drying from t-Bu OH. These α-chitin aerogels exhibited high porosity(87% to 94%), low density(0.09 to 0.19 g/cm^3), high specific surface area(419 to 535 m^2/g) and large pore volume(2.7 to 3.8 cm^3/g). Moreover, the α-chitin aerogels exhibited good mechanical properties under compression and tension models. In vitro studies showed that m BMSCs cultured on chitin hydrogels have good biocompatibility. These nanostructured α-chitin aerogels may be useful for various applications, such as catalyst supports, carbon aerogel precursors and biomedical materials.
