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Tunable microfluidic chip for single-cell deformation study
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作者 Ruiyun Zhang Xuexin Duan +3 位作者 Shuaihua Zhang Wenlan Guo Chen Sun Ziyu Han 《Nanotechnology and Precision Engineering》 EI CAS CSCD 2023年第2期25-32,共8页
Microfluidic phenotyping methods have been of vital importance for cellular characterization,especially for evaluating single cells.In order to study the deformability of a single cell,we devised and tested a tunable ... Microfluidic phenotyping methods have been of vital importance for cellular characterization,especially for evaluating single cells.In order to study the deformability of a single cell,we devised and tested a tunable microfluidic chip-based method.A pneumatic polymer polydimethylsiloxane(PDMS)membrane was designed and fabricated abutting a single-cell trapping structure,so the cell could be squeezed controllably in a lateral direction.Cell contour changes under increasing pressure were recorded,enabling the deformation degree of different types of single cell to be analyzed and compared using computer vision.This provides a new perspective for studying mechanical properties of cells at the single cell level. 展开更多
关键词 MICROFLUIDICS Cell deformation Single cell Computer vision
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Two-Dimensional Photoacoustic Imaging of Blood Vessel Networks within Biological Tissues 被引量:12
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作者 苏翼雄 王瑞康 +1 位作者 张帆 姚建铨 《Chinese Physics Letters》 SCIE CAS CSCD 2006年第2期512-515,共4页
Photoacoustic 断层摄影术(轻拍) 因为它联合优点和光和声音的很引人注目的特征,是为医药诊断的一种强大的成像技术。一个 PAT 试验性的系统在我们由 Q-switchedNd 组成的实验室构造了的 Wedescribe : 钇铝柘榴石脉搏激光与 8-ns 脉搏... Photoacoustic 断层摄影术(轻拍) 因为它联合优点和光和声音的很引人注目的特征,是为医药诊断的一种强大的成像技术。一个 PAT 试验性的系统在我们由 Q-switchedNd 组成的实验室构造了的 Wedescribe : 钇铝柘榴石脉搏激光与 8-ns 脉搏宽度在 532nm 操作产生相片从一件生物样品的声学的信号。二维的相片在织物表面下面的血容器网络 1cm 的声学的成像被完成。我们成功地也证明系统能够成像在有颅骨和皮的前 vivo 老鼠大脑上的血容器未经触动。 展开更多
关键词 二维光声成像 血管网络 生物组织 医学诊断 Q调制激光器
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High-power terahertz radiation from surface-emitted THz-wave parametric oscillator 被引量:5
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作者 李忠洋 姚建铨 +3 位作者 徐德刚 钟凯 汪静丽 邴丕彬 《Chinese Physics B》 SCIE EI CAS CSCD 2011年第5期280-284,共5页
We report a pulsed surface-emitted THz-wave parametric oscillator based on two MgO:LiNbO3 crystals pumped by a multi-longitudinal mode Q-switched Nd:YAG laser.Through varying the phase matching angle,the tunable THzwa... We report a pulsed surface-emitted THz-wave parametric oscillator based on two MgO:LiNbO3 crystals pumped by a multi-longitudinal mode Q-switched Nd:YAG laser.Through varying the phase matching angle,the tunable THzwave output from 0.79 THz to 2.84 THz is realized.The maximum THz-wave output was 193.2 nJ/pulse at 1.84 THz as the pump power density was 212.5 MW/cm 2,corresponding to the energy conversion efficiency of 2.42×10-6 and the photon conversion efficiency of about 0.037%.When the pump power density changed from 123 MW/cm 2 to 148 MW/cm 2 and 164 MW/cm 2,the maximum output of the THz-wave moved to the high frequency band.We give a reasonable explanation for this phenomenon. 展开更多
关键词 参量振荡器 太赫兹波 太赫兹辐射 表面 大功率 能量转换效率 激光泵浦 ND:YAG
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Continuous-wave mid-infrared intracavity singly resonant optical parametric oscillator based on periodically poled lithium niobate 被引量:7
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作者 丁欣 张少敏 +3 位作者 马洪梅 庞明 姚建铨 李卓 《Chinese Physics B》 SCIE EI CAS CSCD 2008年第1期211-216,共6页
This paper reports a continuous-wave (CW) mid-infrared intracavity singly resonant optical parametric oscillator based on periodically poled lithium niobate (PPLN) pumped by a diode-end-pumped CW Nd:YVO 4 laser. Consi... This paper reports a continuous-wave (CW) mid-infrared intracavity singly resonant optical parametric oscillator based on periodically poled lithium niobate (PPLN) pumped by a diode-end-pumped CW Nd:YVO 4 laser. Considering the thermal lens effects, it adopted an optical ballast lens and the near-concentric cavity for better operation. At the PPLN's grating period of 28.5 μm and the temperature of 140 C, the maximum idler output power of 155 mW at 3.86 μm has been achieved when the 808 nm pump power is 8.5 W, leading to an optical-to-optical conversion efficiency of 1.82%. 展开更多
关键词 连续波 红外线 光学参数 振荡器 铌酸锂晶体
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High efficiency continuous-wave tunable signal output of an intracavity singly resonant optical parametric oscillator based on periodically poled lithium niobate 被引量:5
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作者 丁欣 盛泉 +6 位作者 陈娜 禹宣伊 王睿 张衡 温午麒 王鹏 姚建铨 《Chinese Physics B》 SCIE EI CAS CSCD 2009年第10期4314-4318,共5页
In this paper we report on a continuous-wave (CW) intracavity singly resonant optical parametric oscillator (ICSRO) based on periodically poled LiNbO3 (PPLN) pumped by a diode-end-pumped CW Nd:YVO4 laser. Considering ... In this paper we report on a continuous-wave (CW) intracavity singly resonant optical parametric oscillator (ICSRO) based on periodically poled LiNbO3 (PPLN) pumped by a diode-end-pumped CW Nd:YVO4 laser. Considering the thermal lens effects and diffraction loss, an optical ballast lens and a near-concentric cavity are adopted for better operation. Through varying the grating period and the temperature, the tunable signal output from 1406 nm to 1513 nm is obtained. At a PPLN grating period of 29 μm and a temperature of 413 K, a maximum signal output power of 820 mW at 1500 nm is achieved when the 808 nm pump power is 10.9 W, leading to an optical-to-optical conversion efficiency of 7.51%. 展开更多
关键词 周期极化铌酸锂 光参量振荡器 信号输出 连续波 谐振 腔内 ND:YVO4激光器 可调谐
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Selective reflection combined with Fabry-Perot effects from two-level atoms confined between two dielectric walls 被引量:6
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作者 李院院 周瑜 张贵忠 《Chinese Physics B》 SCIE EI CAS CSCD 2006年第5期985-991,共7页
关键词 选择性反射 限制原子水蒸气薄膜 次Doppler结构 电介质墙
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A Low-Pump-Threshold High-Repetition-Rate Intracavity Optical Parametric Generator Based on Periodically Poled Lithium Niobate 被引量:5
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作者 纪峰 张百钢 +6 位作者 李恩邦 周睿 张铁犁 路洋 赵璞 王鹏 姚建铨 《Chinese Physics Letters》 SCIE CAS CSCD 2006年第8期2113-2116,共4页
关键词 阈值 光参量 PPLN 物理光学
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Photonic Crystal Fiber Source of Quantum Correlated Photon Pairs in the 1550 nm Telecom Band 被引量:3
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作者 崔亮 李小英 +2 位作者 范海洋 杨磊 马晓欣 《Chinese Physics Letters》 SCIE CAS CSCD 2009年第4期125-127,共3页
关键词 光子晶体光纤 量子关联 光子对 电信 宽带 纳米 双折射光纤 ps脉冲
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All-fiber optical modulator based on no-core fiber and magnetic fluid as cladding 被引量:3
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作者 陈耀飞 韩群 刘铁根 《Chinese Physics B》 SCIE EI CAS CSCD 2015年第1期315-320,共6页
An all-fiber optical modulator,which is composed of a piece of no-core fiber spliced between two sections of singlemode fibers and uses magnetic fluid(MF)as the cladding of the no-core fiber section,is proposed and in... An all-fiber optical modulator,which is composed of a piece of no-core fiber spliced between two sections of singlemode fibers and uses magnetic fluid(MF)as the cladding of the no-core fiber section,is proposed and investigated experimentally.Due to the tunable refractive index and absorption coefficient of MF,the output intensity can be modulated by controlling an applied magnetic field.The dependences of the modulator’s temporal response on the working wavelength,the magnetic field strength(H),and the MF’s concentration are investigated experimentally.The results are explained qualitatively by the dynamic response process of MF under the action of a magnetic field.The findings are helpful for optimizing this kind of modulator. 展开更多
关键词 光调制器 全光纤 无芯 包层 磁流体 磁场强度 磁性流体 单模光纤
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Location algorithm for seal imprints on Chinese bank-checks based on region growing 被引量:5
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作者 CHEN Li-jiang LIU Tie-gen +3 位作者 CHEN Jia-Jia ZHU Jun-chao DENG Ji-Jie MA She-xiang 《Optoelectronics Letters》 EI 2006年第2期155-157,共3页
The paper focuses on location of seal imprints on Chinese bank-checks based on region growing.Region growing method can be applied to searching and locating connection region in an image.A seal imprint,however,is gene... The paper focuses on location of seal imprints on Chinese bank-checks based on region growing.Region growing method can be applied to searching and locating connection region in an image.A seal imprint,however,is generally composed of various connection regions which are unconnected to each other.In order to locate the seal imprint,these connection regions must be fused together.In the paper,an algorithm for locating seal imprints on Chinese bankchecks based on region growing is proposed, of which a fusion criterion for connection regions in a seal imprint is put forth based on the image feature of Chinese bankcheck,and a center-rays model is proposed to find the topological relationship between connection regions,for which externally-tangent rectangle of region is used as the mark of location of region.The location experiment is achieved with a false-acceptance rate of 7.1% and a false-rejection rate of 0% on Chinese bankcheck. 展开更多
关键词 定位算法 封装技术 图象识别 射线模式
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Interference of selective higher-order modes in optical fibers 被引量:3
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作者 Li Enbang Peng Gangding 《仪器仪表学报》 EI CAS CSCD 北大核心 2007年第3期400-403,共4页
The interference of selective higher-order modes in optical fibers is investigated both theoretically and experimentally. It has been demonstrated that by coupling the LP01 mode in a step-index single-mode fiber (SMF)... The interference of selective higher-order modes in optical fibers is investigated both theoretically and experimentally. It has been demonstrated that by coupling the LP01 mode in a step-index single-mode fiber (SMF) to the LP0m modes in step-index multimode fibers (MMFs) with different parameters, one can selectively generate higher-order modes and construct all-fiber interferometers. The research presented in this paper forms a basis of a new type of fiber devices with potential applications in fiber sensing, optical fiber communications, and optical signal processing. 展开更多
关键词 光纤 多模光纤 单模光纤 多方式干涉
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Threshold Analysis of a THz-Wave Parametric Oscillator 被引量:2
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作者 LI Zhong-Yang 《Chinese Physics Letters》 SCIE CAS CSCD 2010年第6期100-103,共4页
一个兆兆赫波浪的参量的获得参量的振荡器(TPO ) 被分析。同时, TPO 阀值泵紧张的表示与不同因素被导出并且理论上分析了。在泵波浪之间的有效相互作用长度并且司烧波浪被计算,并且特别注意对泵波浪的联合效率被给予并且司烧波浪。如... 一个兆兆赫波浪的参量的获得参量的振荡器(TPO ) 被分析。同时, TPO 阀值泵紧张的表示与不同因素被导出并且理论上分析了。在泵波浪之间的有效相互作用长度并且司烧波浪被计算,并且特别注意对泵波浪的联合效率被给予并且司烧波浪。如此的分析为 TPO 的实验是有用的。[从作者抽象] 展开更多
关键词 参量振荡器 太赫兹波 阈值分析 STOKES波 TPO 增益参数 耦合效率 表达式
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Investigation of pump-wavelength dependence of terahertz-wave parametric oscillator based on LiNbO_3 被引量:2
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作者 孙博 刘劲松 +1 位作者 李恩邦 姚建铨 《Chinese Physics B》 SCIE EI CAS CSCD 2009年第7期2846-2852,共7页
This paper investigates the performances of terahertz-wave parametric oscillators(TPOs) based on the LiNbO 3 crystal at different pump wavelengths.The calculated results show that TPO characteristics,including the fre... This paper investigates the performances of terahertz-wave parametric oscillators(TPOs) based on the LiNbO 3 crystal at different pump wavelengths.The calculated results show that TPO characteristics,including the frequency tuning range,the THz-wave gain and the stability of THz-wave output direction based on the Si-prism coupler,can be significantly improved by using a short-wavelength pump.It also demonstrates that a long-wavelength-pump allows the employment of a short TPO cavity due to an enlarged phase-matching angle,that is,an increased angular separation between the pump and oscillated Stokes beams under the THz-wave generation at a specific frequency.The study provides an useful guide and a theoretical basis for the further improvement of TPO systems. 展开更多
关键词 参量振荡器 铌酸锂晶体 太赫兹波 长波长 频率调谐范围 城市规划 棱镜耦合器
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Reflection-type electromagnetically induced transparency analogue in terahertz metamaterials 被引量:2
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作者 丁春峰 张雅婷 +3 位作者 姚建铨 孙崇玲 徐德刚 张贵忠 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第12期187-190,共4页
A reflection-type electromagnetically induced transparency(EIT) metamaterial is proposed, which is composed of a dielectric spacer sandwiched with metallic patterns and metallic plane. Experimental results of THz time... A reflection-type electromagnetically induced transparency(EIT) metamaterial is proposed, which is composed of a dielectric spacer sandwiched with metallic patterns and metallic plane. Experimental results of THz time domain spectrum(THz-TDS) exhibit a typical reflection of EIT at 0.865 THz, which are in excellent agreement with the full-wave simulations. A multi-reflection theory is adopted to analyze the physical mechanism of the reflection-type EIT, showing that the reflection-type EIT is a superposition of multiple reflection of the transmission EIT. Such a reflection-type EIT provides many applications based on the EIT effect, such as slow light devices and nonlinear elements. 展开更多
关键词 太赫兹时域光谱 电磁感应透明 反射式 模拟 材料 金属图案 EIT 非线性元件
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Color Tunable Light-Emitting Diodes Based on Polymer/Inorganic Heterojunction 被引量:3
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作者 谭海曙 陈立春 +4 位作者 王向军 姚建栓 鞠传喜 谢洪泉 高广华 《Chinese Physics Letters》 SCIE CAS CSCD 1998年第2期137-139,共3页
By using p-type polymer poly(2,5-Didodecyloxy-1,4-Phenylenylenevinylene)(PDDOPV)and n-type inorganic material ZnO:Zn,the electronluminescent(EL)emission from bilayer device based on polymer/inorganic hetero-junction w... By using p-type polymer poly(2,5-Didodecyloxy-1,4-Phenylenylenevinylene)(PDDOPV)and n-type inorganic material ZnO:Zn,the electronluminescent(EL)emission from bilayer device based on polymer/inorganic hetero-junction was successfully demonstrated.In comparison with single layer polymer device,with dc voltage of 10V,the brightness and luminous efficiency of bilayer device were enhanced 14 and 26 times,respectively.The EL spectrum of bilayer device is not identical to the characteristic emission spectrum of either PDDOPV or ZnO:Zn,and shifts continuously towards to short wavelength direction as the applied voltage increases. 展开更多
关键词 LUMINOUS INORGANIC SPECTRUM
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Theoretical study of phase-matching properties for tunable terahertz-wave generation in isotropic nonlinear crystals 被引量:2
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作者 SUN Bo YAO Jian-quan +2 位作者 ZHANG Bai-gang ZHANG Tie-li WANG Peng 《Optoelectronics Letters》 EI 2007年第2期152-156,共5页
Theoretical investigation of the phase-matching properties for the tunable coherent terahertz wave generation in the isotro- pic semiconductor nonlinear materials of CdTe and GaP is presented according to their optica... Theoretical investigation of the phase-matching properties for the tunable coherent terahertz wave generation in the isotro- pic semiconductor nonlinear materials of CdTe and GaP is presented according to their optical dispersion properties, based on a pulsed dual-wavelength KTP-OPO operating near degenerate point in the process of the difference frequency mixing. The cross-Reststrahlen band dispersion compensation phase-matching technique involved in this interaction is introduced concisely. The optimum lengths of DFG crystals are decided according to the minimum coherence lengths of the crystals in the given pump wavelength ranges. The results of analysis and calculation provide the useful and necessary theoretical basis and guidance for the future experiments. 展开更多
关键词 各向同性 非线性晶体 可调谐太赫波发生 周相匹配性质
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Photon statistics of pulse-pumped four-wave mixing in fiber with weak signal injection 被引量:1
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作者 刘楠楠 刘宇宏 +1 位作者 李嘉敏 李小英 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第7期229-233,共5页
We study the photon statistics of pulse-pumped four-wave mixing in fibers with weak coherent signal injection by measuring the intensity correlation functions of individual signal and idler fields. The experimental re... We study the photon statistics of pulse-pumped four-wave mixing in fibers with weak coherent signal injection by measuring the intensity correlation functions of individual signal and idler fields. The experimental results show that the intensity correlation function of individual signal(idler) field g_(s(i))^(2) decreases with the intensity of signal injection. After applying narrow band filter in signal(idler) band, the value of g_(s(i))^(2) decreases from 1.9 ± 0.02(1.9 ± 0.02) to 1.03 ± 0.02(1.05 ± 0.02) when the intensity of signal injection varies from 0 to 120 photons/pulse. The results indicate that the photon statistics changes from Bose–Einstein distribution to Poisson distribution. We calculate the intensity correlation functions by using the multi-mode theory of four-wave mixing in fibers. The theoretical curves well fit the experimental results.Our investigation will be useful for mitigating the crosstalk between quantum and classical channels in a dense wavelength division multiplexing network. 展开更多
关键词 信号注入法 光子统计 脉冲泵浦 四波混频 光纤 强度相关函数 玻色-爱因斯坦分布 密集波分复用网络
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Low-loss terahertz waveguide with InAs-graphene-SiC structure 被引量:1
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作者 徐德刚 王与烨 +8 位作者 于红 李佳起 李忠孝 闫超 张昊 刘鹏翔 钟凯 王卫鹏 姚建铨 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第5期323-327,共5页
We demonstrate a low-loss terahertz waveguide based on the InAs-graphene-SiC structure. By analyzing the terahertz waveguide proposed in this paper, we can obtain that it is the characteristic of a low transmission lo... We demonstrate a low-loss terahertz waveguide based on the InAs-graphene-SiC structure. By analyzing the terahertz waveguide proposed in this paper, we can obtain that it is the characteristic of a low transmission loss coefficient(αloss≈0.55 dB/m) for fundamental mode(LP01) when the incident frequency is larger than 3.0 THz. The critical radii of the inside and outside cylinders have been found for the high-quality transmission. The large inside radius and the high transmission frequency result in a flat transmission loss coefficient curve. As a strictly two-dimensional material, the double graphene surface rings perform better to improve the quality of transmission mode. These results provide a new idea for the research of the long-distance THz waveguide. 展开更多
关键词 太赫兹 低损耗 硅结构 波导 石墨 SIC 质量传输 损耗系数
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High-Quality Continuous-Wave Imaging with a 2.53 THz Optical Pumped Terahertz Laser and a Pyroelectric Detector 被引量:1
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作者 邴丕彬 姚建铨 +2 位作者 徐德刚 徐小燕 李忠洋 《Chinese Physics Letters》 SCIE CAS CSCD 2010年第12期96-98,共3页
一个 cw 兆兆赫(THz ) 传播成像系统被表明,一幅高质量的 THz 图象能用一个热电的察觉者被获得。影响成像质量的因素例如 THz 波长,在样品表面,马达的步骤长度,和 chopper 的频率上看到尺寸,理论上并且试验性地被调查。试验性的结... 一个 cw 兆兆赫(THz ) 传播成像系统被表明,一幅高质量的 THz 图象能用一个热电的察觉者被获得。影响成像质量的因素例如 THz 波长,在样品表面,马达的步骤长度,和 chopper 的频率上看到尺寸,理论上并且试验性地被调查。试验性的结果证明 THz 图象的最大的分辨率能与 118.8mm, 1.8mm 的点尺寸和 0.25mm 的步骤长度的 THz 波长到达 0.4mm。[从作者抽象] 展开更多
关键词 太赫兹成像 热释电探测器 泵浦激光器 品质 连续波 成像质量 系统论 分辨率
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Spectra of spontaneous Raman scattering in taper-drawn micro/nano-fibers 被引量:1
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作者 徐颖鑫 崔亮 +5 位作者 李小英 郭骋 李宇航 徐忠扬 王力军 方伟 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第12期266-270,共5页
We study the spontaneous Raman scattering(RS) in taper-drawn micro/nano-fibers(MNFs) by employing the photon counting technique. The spectra of RS in five MNFs, which are fabricated by using different heating flames(h... We study the spontaneous Raman scattering(RS) in taper-drawn micro/nano-fibers(MNFs) by employing the photon counting technique. The spectra of RS in five MNFs, which are fabricated by using different heating flames(hydrogen flame or butane flame) and with different diameters, are measured within a frequency shift range of 1435 cm^(-1)–3200 cm^(-1).From the measured spectra, we observe the RS peaks originated from silica and a unique RS peak with a frequency shift of ~ 2905 cm^(-1)(~ 87.2 THz). Unlike the former ones, the latter one is not observable in conventional optical fibers.Furthermore, the unique peak becomes obvious and starts to rapidly increase with the decrease of the diameter of MNFs when the diameter is smaller than 2 μm, and the intensity of the unique peak significantly depends on the heating flame used in the fabricating process. Our investigation is useful for the entanglement generation or optical sensing using taper-drawn MNFs. 展开更多
关键词 拉曼散射光谱 纳米纤维 光纤直径 锥形 氢火焰 计数技术 遥感光谱 二氧化硅
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