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Perception of Nursing and Midwifery Trainees towards Clinical Environment at Cape Coast in the Central Region of Ghana
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作者 Monica Salakpi Christiana Asiedu +2 位作者 Dorcas Frempomaa Agyare Rita Opoku-Danso Anita Davis 《Open Journal of Nursing》 2022年第10期709-723,共15页
Purpose: The purpose of this study was to investigate the perception of students’ nurses in the nurses training colleges towards clinical environment. Methodology: A cross-sectional survey approach was used. Nursing ... Purpose: The purpose of this study was to investigate the perception of students’ nurses in the nurses training colleges towards clinical environment. Methodology: A cross-sectional survey approach was used. Nursing and Midwifery trainees at Cape Coast were the respondents. Simple random sampling was used to select 605 respondents for the study. Descriptive and inferential statistics were employed to analyze the data. Results: The majority of the respondents were female, Christians, singled and attended Cape Coast Nursing and Midwifery Training College (CCNMTC). The staff were helpful, friendly and considerate. There were repetition of student’s tasks in every shift but new and different ways of teaching were used. The students had positive perception of clinical learning environment. There were statistically significant differences in perception towards clinical learning environment among students based on academic class (levels). Conclusion: It was recommended that the staff nurses should assign students with varied task depending on their level. 展开更多
关键词 Clinical Education Clinical Learning Environment Clinical Skill Acquisition PERCEPTION
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Dysphagia and daily oral fluids among cerebrovascular stroke patients:an theory-based nursing intervention protocol
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作者 Zeinab Hussein Ali Marwa Abd-Elaziz Amany Abdrbo 《Frontiers of Nursing》 2023年第2期213-222,共10页
Objective:To evaluate the improvement of dysphagia and the daily amounts of oral fluids served among people who had recently experienced a cerebrovascular stroke(CVS)after applying a nursing intervention protocol.Meth... Objective:To evaluate the improvement of dysphagia and the daily amounts of oral fluids served among people who had recently experienced a cerebrovascular stroke(CVS)after applying a nursing intervention protocol.Methods:A quasi-experimental design was used to examine 60 stroke patients who were randomly and alternatively divided equally into a study group and a control group.Gugging Swallowing Screen(GUSS)and fluid balance chart were used.Within the first 24 h of a patient’s admission,expert nurses were trained in nursing intervention protocol to manage dysphagia and daily oral fluids.Results:Post-nursing intervention,the severity of dysphagia decreased among the study group more than in the control group.Additionally,the study group began taking greater amounts of fluids by the oral route than before the nursing intervention.Conclusions:A standardized nursing intervention protocol is needed to decrease the severity of dysphagia after CVS and increase the amount of daily oral fluids.The presence of a structured theory-based nursing intervention protocol for dysphagia management will greatly contribute to decreasing the consequences of dysphagia after CVS,and can also be expected to attenuate the effects of aspiration pneumonia,dehydration,and malnutrition;further,it also increases adherence to the protocol by both nurses and patients. 展开更多
关键词 DYSPHAGIA EVIDENCE-BASED health behavior nursing intervention oral fluid serving STROKE
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Betalains protect various body organs through antioxidant and anti-inflammatory pathways
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作者 Nilesh Prakash Nirmal Seema Medhe +4 位作者 Merina Dahal Pankaj Koirala Siriwan Nirmal Fahad Al-Asmari Baojun Xu 《Food Science and Human Wellness》 SCIE CSCD 2024年第3期1109-1117,共9页
Betalains are natural coloring pigments with betalamic acid as the core structure of all subclasses.Besides their coloring properties,betalains exhibit various biological activities,including antioxidant and anti-infl... Betalains are natural coloring pigments with betalamic acid as the core structure of all subclasses.Besides their coloring properties,betalains exhibit various biological activities,including antioxidant and anti-inflammatory properties,which are highly imperative.Further in-vivo studies reported that betalains protect various body organs,leading to health enhancement.Body organs,including the heart,liver,kidney,lung,etc.,are important for a healthy life.However,these organs can be affected or damaged by various stress factors,toxicants,and harmful substances.Recent studies have claimed that betalains could protect all vital organs of the body through antioxidant and anti-inflammatory mechanisms.This review article described the in-vivo antioxidant and anti-inflammatory activities of betalains in various cell-line or animal models.A comprehensive discussion has been provided on the mechanism of action of betalains in protecting various body organs,including cardio-protective effect,hepato-protective ability,renal protection capacity,repro-protective ability,neuro-protective effect,lung protection,and gut protection ability.Finally,future research directions and conclusions have been outlined. 展开更多
关键词 BETALAINS ANTIOXIDANT ANTI-INFLAMMATORY BIOACTIVITIES Ogans-protection
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Factors influencing discharge readiness among patients with mild-to-moderate ischemic stroke:a cross-sectional study
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作者 Li-Fei Wang Niphawan Samartkit Khemaradee Masingboon 《Frontiers of Nursing》 2024年第1期57-66,共10页
Objective:To describe discharge readiness and determine whether self-efficacy,social support,and the quality of discharge teaching can predict discharge readiness among patients with mild-to-moderate ischemic stroke.M... Objective:To describe discharge readiness and determine whether self-efficacy,social support,and the quality of discharge teaching can predict discharge readiness among patients with mild-to-moderate ischemic stroke.Methods:A total of 120 patients with mild-to-moderate ischemic stroke were recruited using simple random sampling.Five instruments,namely,the Demographic Data Questionnaire,the Chinese version of the Readiness for Hospital Discharge Scale(RHDS_C),the SelfEfficacy for Managing Chronic Disease 6-Item Scale(SES6),the Perceived Social Support Scale(PSSS),and the Quality of Discharge Teaching Scale(QDTS),were used for data collection.Descriptive statistics and standard multiple linear regression were used for data analysis.Results:The mean score of discharge readiness among patients with mild-to-moderate ischemic stroke was at a moderate level(M=7.6,SD=0.92),and 75.8%of the participants felt ready for discharge.Standard multiple linear regression revealed that selfefficacy(β=0.62,P<0.001)and the quality of discharge teaching(β=0.28,P<0.001)were the influencing factors.However,social support could not predict discharge readiness significantly.All the factors combined explained 64.9%of the variance in discharge readiness.Conclusions:Intervention programs aimed at improving self-efficacy and the quality of discharge teaching may be helpful in promoting discharge readiness in patients with mild-to-moderate ischemic stroke,especially in coping ability. 展开更多
关键词 discharge readiness ischemic stroke quality of discharge teaching SELF-EFFICACY social support
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Reliability and validation of the Arabic version of the Conditions for Workplace Effectiveness Questionnaire-Ⅱ 被引量:1
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作者 Wafa'a F.Ta'an Mohammed M.Al-Hammouri +1 位作者 Jehad A.Rababah Mohammad M.Suliman 《International Journal of Nursing Sciences》 CSCD 2021年第2期215-220,I0006,共7页
Objective:This study aimed to examine the psychometric properties of the Conditions for Workplace Effectiveness Questionnaire-Ⅱ-Arabic Version(CWEQ-Ⅱ-AV),which measures structural empowerment among nurses.To enhance... Objective:This study aimed to examine the psychometric properties of the Conditions for Workplace Effectiveness Questionnaire-Ⅱ-Arabic Version(CWEQ-Ⅱ-AV),which measures structural empowerment among nurses.To enhance the usability and credibility of the CWEQ-Ⅱ among researchers within Arabicspeaking countries,a valid and reliable Arabic version of the measure is necessary.Methods:A cross-sectional research design was used.From December 2018 to June 2019,275 nurses working in 4 hospitals participated in the study.Reliability was assessed by examining internal consistency and split-half reliability.A confirmatory factor analysis was performed to evaluate the factor structure of the CWEQ-Ⅱ-AV.Results:The psychometric properties of the CWEQ-Ⅱ-AV were excellent regarding the six-factor model(opportunity,information,resources,support,formal power,and informal power).The results showed the following fit indices meet the criteria set a priori:comparative fit index(CFI)=0.96,root mean square of error approximation(RMSEA)=0.06,andХ^(2)/df=2.08.Cronbach's a coefficient was 0.95 for the total questionnaire and ranged between 0.83 and 0.89 for the individual subscales.The split-half reliability was 0.91 for the total questionnaire and ranged from 0.83 to 0.87 for individual subscales.Conclusion:This study provides evidence that CWEQ-Ⅱ-AV is both a reliable and valid measure of structural empowerment among Arab nurses. 展开更多
关键词 EMPOWERMENT Hospital nursing staff Nursing administration research PSYCHOMETRICS JORDAN
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Comparing Lifestyle Convenience of Multiple Daily Injection and Continuous Subcutaneous Insulin Infusion
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作者 Ikuko Nishio 《Open Journal of Nursing》 2017年第12期1365-1374,共10页
Aim: This study investigated the lifestyle convenience of Insulin therapy for adult women patients with type 1 diabetes. Methods: Participants were type 1 diabetes adult women patients who switched from multiple daily... Aim: This study investigated the lifestyle convenience of Insulin therapy for adult women patients with type 1 diabetes. Methods: Participants were type 1 diabetes adult women patients who switched from multiple daily injection (MDI) therapy to Continuous Subcutaneous Insulin Infusion (CSII) therapy. We conducted semi-structured interviews with participants. To analyze, we referenced the classification table of Hamada’s study comparing the usefulness of both the NovoPen? and CSII. Semi-structured interviews were conducted with the research subjects. The questions focused mainly on diabetes management, instrument operation, everyday life, and social, psychological and lifestyle convenience aspects during MDI and CSII. Results: Research subjects were 4 women patients with type 1 diabetes. The average age was 35.3 ± 6.24 (SE) years old. Participants were undergoing MDI therapy;however, in the middle, they switched to CSII therapy. CSII therapy is convenient in terms of diabetes management, social and psychological. MDI therapy is convenient in terms of instrument operation and daily life. Compared to MDI therapy, CSII therapy is less convenient in terms of instrument operation and everyday life. However, since CSII therapy has more stable HbA1c and blood glucose levels compared to MDI therapy, it is more convenient in terms of social and psychological aspects and reduces those burdens. About economy CSII therapy, patients paid about 5000 yen more per month compared to MDI therapy. Conclusion: It is believed that patients prioritize therapeutic effects, and choose CSII, which is stable in psychological and social aspects, even though it is inconvenient with life. 展开更多
关键词 Insulin INFUSION Systems LIFESTYLE Disease Management MULTIPLE DAILY INJECTION Type 1 Diabetes Women’s Health
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Growth of the Pulmonary Valve Annulus after the Modified Blalock-Taussig Shunt in Patients with Tetralogy of Fallot
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作者 Siraphop Thapmongkol Jarun Sayasathid +5 位作者 Jessada Methrujpanont Kanthachat Thatsakorn Worawan Jittham Suwanna Puitm Methiniwiran Thapmongkol Jule Namchaisiri 《Congenital Heart Disease》 SCIE 2021年第5期433-441,共9页
Background:The surgical outcomes of tetralogy of Fallot(TOF)have evolved dramatically and have resulted in lower mortality rate.Currently,the many cardiac centers have a trend to early single-stage complete repair mor... Background:The surgical outcomes of tetralogy of Fallot(TOF)have evolved dramatically and have resulted in lower mortality rate.Currently,the many cardiac centers have a trend to early single-stage complete repair more than a staged repair.However,the patients who have an early primary repair were required transannular patch augmentation of a pulmonary valve frequently.This effect has been developed a chronic pulmonary insufficiency may lead to right ventricular dilation,dysfunction.In this era,the aim of treatment of TOF is attempted to preserve pulmonary valve annulus for prevent right ventricular dysfunction in the future.The systemic to pulmonary artery shunt is a palliative procedure or known as staged repair for symptomatic patients with TOF.The modified Blalock-Taussig shunt(mBTS)is the most useful systemic to pulmonary shunt and perform as an initial procedure before complete repair.The mBTS can provide increase pulmonary blood flow as well as improve oxygenation and also promote pulmonary artery(PA)growth.However,the effect of this procedure to promote growth of a pulmonary valve annulus is still debate.Objectives:To compare a growth of pulmonary valve annulus between after staged repair and primary repair in patients with TOF(without pulmonary atresia).Methods:A retrospective case-control study,review of patients with TOF underwent total repair at our hospitals from January 2005 and December 2017 was performed,a total number of 112 patients underwent TOF repair.Twenty-nine patients(26%)underwent a staged repair(mBTS group)and 83(74%)underwent total repair only or primary repair(PR group).We evaluated diameter of pulmonary valve annulus by using echocardiography at the time of first diagnosis and before complete repair on both groups.Results:The age of diagnosis of mBTS group were younger than PR group(p=0.011).Therefore,pulmonary valve annuls were smaller in mBTS group.(Z-score,−2.93±1.42 vs.−1.89±0.97;p=0.001).However,the growth potential of pulmonary valve annulus was increase more than PR group significantly(Z-score,−1.46±1.02 vs.−2.11±1.19;p=0.009)Even though a patent ductus arteriosus was found commonly in PR group(p=0.018).Conclusions:Our results suggest the systemic to pulmonary shunt or mBTS can promote growth of pulmonary valve annulus in patients with TOF. 展开更多
关键词 Tetralogy of Fallot systemic to pulmonary shunt modified Blalock-Taussig shunt pulmonary valve annulus pulmonic valve Z score
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Relationship between Self-Care and Hand Foot Syndrome Specific Quality of Life in Cancer Patients
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作者 Naoko Mikoshiba Noriko Yamamoto-Mitani +2 位作者 Kazuki Sato Yukari Yaju Mitsunori Miyashita 《Open Journal of Nursing》 2016年第2期100-109,共10页
Purpose: The purpose of this study was to describe adherence to self-care for hand-foot syndrome (HFS) and the relationship between self-care and health-related quality of life (QOL). Methods: A cross-sectional study ... Purpose: The purpose of this study was to describe adherence to self-care for hand-foot syndrome (HFS) and the relationship between self-care and health-related quality of life (QOL). Methods: A cross-sectional study was conducted on 105 consecutive outpatients with HFS. To assess self-care for HFS and QOL, the participants were asked to complete self-care and HFS-14 (hand-foot syndrome specific QOL) questionnaires, respectively. Multiple regression models were used to identify the relationship between self-care and QOL. Results: Adherence to self-care for HFS was low, less than 50% for most of the items. Multivariate analysis revealed that poorer self-care (βs = -0.19;P = 0.03), depressive symptoms (βs = 0.43;P βs = 0.20;P = 0.04) were independent predictors of poorer QOL scores. Conclusions: We have identified a need for further research to develop effective programs of self-care in HFS. 展开更多
关键词 CHEMOTHERAPY Hand-Foot Syndrome NEOPLASM Quality of Life Supportive Care
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A qualitative study to explain the criteria of nursing managers in selecting effective nursing diagnosis
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作者 Alaa Jawad Kadhim Mohammad Abbasinia +4 位作者 Mina Abolfazli Zahra Hezbiyan Hanie Dahmardeh Bahman Aghaie Reza Norouzadeh 《Frontiers of Nursing》 2024年第4期469-478,共10页
Objective:This study aimed to explain the criteria of managers at different levels of nursing in selecting effective nursing diagnosis.Methods:In conventional content analysis,10 nursing managers at different levels i... Objective:This study aimed to explain the criteria of managers at different levels of nursing in selecting effective nursing diagnosis.Methods:In conventional content analysis,10 nursing managers at different levels including head nurse,supervisor,and nursing manager were interviewed.Data was collected with semi-structured interviews and a narrative approach.Data analysis was performed using the Zhang–Wildemuth method simultaneously with sampling.Results:Four head nurses,four supervisors(educational,clinical),and two nursing managers were interviewed.The results of the a nalysis led to the extraction of two main categories:centrality of the nursing profession,with the sub-categories compatibility with nursing p ractices and compliance with organizational and professional principles of nursing,and covering the patient care aspect,with s ub-categories of having potential to facilitate and adapting to patient care conditions.Conclusions:The analysis of the views of nursing managers shows that health managers should consider various management aspects such as functional and organizational to increase the efficiency of nursing interventions in the selection of nursing diagnostic systems.From the point of view of health managers,nursing diagnoses should cover the considerations of patients,nurses,and work environments. 展开更多
关键词 intensive care unit nursing diagnosis nursing managers qualitative research conventional content analysis
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Factors Affecting Catecholamines in Caregivers of Patients with De­mentia
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作者 Akemi Hirano Yusuke Suzuki +2 位作者 Toshio Hayashi Koichiro Ina Joji Onishi 《Journal of Geriatric Medicine》 2021年第1期32-37,共6页
Background:Caregivers of dementia patients have significantly higher levels of serum IL-6 and CRP compared to non-caregivers,and the ac­cumulation of everyday stressors reportedly promotes the induction of inflam... Background:Caregivers of dementia patients have significantly higher levels of serum IL-6 and CRP compared to non-caregivers,and the ac­cumulation of everyday stressors reportedly promotes the induction of inflammatory markers.However,few studies have identified factors that affect catecholamine levels in caregivers who experience a combination of physical and mental stress from caregiving.Purpose:This study aimed to identify physical factors that impact catecholamine levels in caregivers of dementia patients.Methods:Participants were elderly caregivers living together with elderly Alzhei­mer’s-type dementia patients.We performed logistic regression analysis,with levels of adrenaline,noradrenaline,and dopamine(indicators of catecholamine)as dependent variables.Results:Caregiver BMI had a significant impact on adrenaline levels(OR:0.792;95%CI:0.654-0.960)and noradrenaline levels(OR:1.210;95%CI:1.009-1.451),whereas age had a significant impact on dopamine levels(OR:1.162;95%CI:1.019-1.324).Discussion:While caregiver BMI significantly impacted adrenaline and noradrenaline levels,the mechanism underlying these relationships is unclear.One possibility is that obesity(BMI)and a rise in sympathetic nerve activity contributed to hypertension.Our findings suggest that chronic stress in elderly caregivers may potentially impair the dopaminergic activation system in the brain.Conclusion:There is a need to identify factors which increase BMI in caregivers.Future studies aimed at gaining a better understanding of the lifestyle habits of caregiv­ers and intervention studies aimed at reducing their BMI are warranted. 展开更多
关键词 Age BMI Caregiver burden CATECHOLAMINE DEMENTIA
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Effects of Free Time on Quality of Life in Elderly Caregivers
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作者 Akemi Hirano Yusuke Suzuki +2 位作者 Toshio Hayashi Koichiro Ina Joji Onishi 《Journal of Geriatric Medicine》 2021年第1期26-31,共6页
Caregivers who contribute to health care of their patients are significantly more likely to experience emotional difficulty,physical difficulty,and financial difficulty,than caregivers who do not contribute.This study... Caregivers who contribute to health care of their patients are significantly more likely to experience emotional difficulty,physical difficulty,and financial difficulty,than caregivers who do not contribute.This study aimed to examine the effects of free time on health-related quality of life among elderly caregivers of dementia patients.In the intervention group,caregivers set aside free time every 30 minutes three times a week,while continuing to care for patients.During the free time,caregivers were free to spend time at home and do whatever they wanted.The control group received only usual care.The intervention period was six months.The Vi­tality subscale score of the SF-36 decreased significantly in the interven­tion group,despite more than half(57.1%)of participants showing im­provements or no change in the rank of this subscale relative to baseline,as assessed by the Wilcoxon signed-rank test(not significant).Caregivers indicated that daily caregiving resulted in an accumulation of physical fatigue,and they continued to have little mental leeway.Caregivers also had difficulty securing free time,which may have hindered improvements to their vitality.There is a need to develop a home-based program that can alleviate caregiver stress and improve their quality of life. 展开更多
关键词 Free time DEMENTIA Elderly caregiver Quality of life
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Factors related to self-management behavior among persons with mild-to-moderate chronic obstructive pulmonary disease in Wenzhou,China
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作者 Xiao-Wen Sheng Niphawan Samartkit Khemaradee Masingboon 《Frontiers of Nursing》 2023年第4期445-455,共11页
Objective:To describe the self-management(SM)behavior among persons with mild-to-moderate chronic obstructive pulmonary disease(COPD),and it examines the correlation between COPD knowledge,self-efficacy,perceived soci... Objective:To describe the self-management(SM)behavior among persons with mild-to-moderate chronic obstructive pulmonary disease(COPD),and it examines the correlation between COPD knowledge,self-efficacy,perceived social support,and SM behavior among persons with mild-to-moderate COPD in Wenzhou,China.Methods:A simple random sampling technique was used to recruit 121 persons with mild-to-moderate COPD who visited the respiratory outpatient department of the First Affiliated Hospital of Wenzhou Medical University in Wenzhou,China.Research instruments include a demographic data questionnaire,COPD SM scale,COPD knowledge questionnaire,6-item chronic disease self-efficacy scale,and perceived social suppor t scale.Descriptive statistics and Pearson's Correlation were used for data analysis.Results:The findings show that the mean score of COPD SM scale was 2.70(SD=0.45).The Pearson correlation analysis revealed that the COPD knowledge(r=0.47,P<0.001),self-efficacy(r=0.28,P=0.001),and perceived social support(r=0.48,P<0.001)were positively correlated to the COPD SM behavior among persons with mild-to-moderate COPD in Wenzhou,China.Conclusions:The findings indicate that disease knowledge,self-efficacy,and perceived social support were related to SM behavior in persons with mild-to-moderate COPD,which provides a theoretical basis for developing SM interventions for persons with mildto-moderate COPD and improving this population's SM behavior. 展开更多
关键词 COPD knowledge mild-to-moderate COPD perceived social support SELF-EFFICACY self-management behavior
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Big data can help prepare nurses and improve patient outcomes by improving quality,safety,and outcomes
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作者 Muayyad Ahmad Salam H.Bani Hani +1 位作者 Mohammad Abu Sabra Omar Almahmoud 《Frontiers of Nursing》 2023年第2期241-248,共8页
Objectives:Big data has revolutionized nursing and health care and raised concerns.This research aims to help nurses understand big data sets to provide better patient care.Methods:This study used big data in nursing ... Objectives:Big data has revolutionized nursing and health care and raised concerns.This research aims to help nurses understand big data sets to provide better patient care.Methods:This study used big data in nursing to improve patient care.Big data in nursing has sparked a global revolution and raised concerns,but few studies have focused on helping nurses understand big data to provide the best patient care.This systematic review was conducted based on PRISMA guidelines.PubMed,MEDLINE,CINAHL,Google Scholar,and ResearchGate were used for 2010-2020 studies.Results:The most common use of big data in nursing was investigated in eight papers between 2015 and 2018.All research showed improvements in patient outcomes and healthcare delivery when big data was used in the medical-surgical,emergency department,critical care unit,community,systems biology,and leadership applications.Big data is not taught to nurses.Conclusions:Big data applications in nursing and health care improve early intervention and decision-making.Big data provides a comprehensive view of a patient’s status and social determinants of health,allowing treatment using all metaparadigms and avoiding a singular focus.Big data can help prepare nurses and improve patient outcomes by improving quality,safety,and outcomes. 展开更多
关键词 big data HEALTH NURSING PRISMA quality of care
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Accuracy of a new rapid diagnostic test for urinary antigen detection and assessment of drug treatment in opisthorchiasis
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作者 Chanika Worasith Jiraporn Sithithaworn +13 位作者 Phattharaphon Wongphutorn Chutima Homwong Kanoknan Khongsukwiwat Anchalee Techasen Kulthida Y.Kopolrat Watcharin Loilome Nisana Namwat Bandit Thinkamrop Chaiwat Tawarungruang Attapol Titapun Thewarach Laha Ross H.Andrews Simon D.Taylor‑Robinson Paiboon Sithithaworn 《Infectious Diseases of Poverty》 SCIE CAS CSCD 2023年第6期79-90,共12页
Background Screening for opisthorchiasis,a parasitic worm infection affecting many millions of people in Southeast Asia,has traditionally relied on faecal egg examination such as the formalin-ethyl acetate concentrati... Background Screening for opisthorchiasis,a parasitic worm infection affecting many millions of people in Southeast Asia,has traditionally relied on faecal egg examination such as the formalin-ethyl acetate concentration technique(FECT)and Kato-Katz method.Although the urinary enzyme-linked immunosorbent assay(ELISA)has been used more recently,we developed a urinary antigen-based rapid diagnostic test(RDT)to simplify diagnosis and as a point-of-care testing(POCT)and field applications for surveillance and control of opisthorchiasis.Methods A urinaryOpisthorchis viverrini(OV)-RDT was developed using immunochromatographic methodology with a specific monoclonal antibody against OV.The diagnostic performance of the urinary OV-RDT was compared to that of quantitative faecal FECT and urinary antigen ELISA(n=493).Cross-reactivities of urinary OV-RDT with other helminthiases coexisted withO.viverrini were determined(n=96).A field trial in the application of urinary OV-RDT was compared with urinary antigen ELISA at baseline screening and assessment of drug treatment outcomes in opisthorchiasis(n=1629).The McNemar chi-square,Kruskal-Wallis and Cohen’s kappa coefficient(κ-value)tests were used for statistical analyses.Results Urinary OV-RDT had sensitivity of 94.2%and specificity of 93.2%,compared to faecal FECT.Urinary OV-RDT had high diagnostic agreement(Kappa=0.842-0.874,P<0.001)and quantitative correlation with urinary antigen ELISA(Kruskal-Wallis tests=316.2,P<0.0001)and faecal FECT(Kruskal-Wallis tests=362.3,P<0.0001).The positive rates by OV-RDT,ELISA and FECT were 48.9%,52.5%and 49.3%,respectively.Cross-reactions of urinary OV-RDT with other helminthiases were few(2%).Field trials of urinary OV-RDT yielded comparable prevalence ofO.viverrini between urinary OV-RDT(53.2%)and urinary antigen ELISA(54.0%).OV screening showed high diagnostic agreement(kappa>0.8,P<0.0001)between urinary OV-RDT and urinary antigen ELISA.The cure rates of opisthorchiasis at 1 month post-praziquantel treatment determined by urinary OV-RDT(86.6%)and urinary antigen ELISA(80.5%)were similar(P>0.05).Conclusions The urinary OV-RDT test has high potential as a new tool for screening and evaluating treatment outcomes in opisthorchiasis.The ease of sample collection and simplicity of urinary OV-RDT may facilitate mass screening,control and elimination of opisthorchiasis,thereby contributing to a reduction in the disease burden in Southeast Asia. 展开更多
关键词 Liver fluke Opisthorchis viverrini Urinary antigen detection Urinary Opisthorchis viverrini rapid diagnosis test Enzyme-linked immunosorbent assay Quantitative formalin-ethyl acetate concentration technique
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Biosafety and biosecurity in the Iraqi Kurdistan Region:Challenges and necessities
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作者 Karzan Qurbani Safin Hussein +3 位作者 Sirwan Khalid Ahmed Hanaw Darwesh Seenaa Ali Haider Hamzah 《Journal of Biosafety and Biosecurity》 2024年第2期65-66,共2页
Dear Dr.Jianguo Xu,The recent COVID-19 pandemic has markedly increased our awareness of the inherent dangers in managing infectious agents like SARS-CoV-2 and highlighted the crucial need to improve laboratory facilit... Dear Dr.Jianguo Xu,The recent COVID-19 pandemic has markedly increased our awareness of the inherent dangers in managing infectious agents like SARS-CoV-2 and highlighted the crucial need to improve laboratory facilities,equipment,and training for technicians to reduce the risks associated with handling these agents.The imperative to evolve laboratory designs and adopt stringent safety guidelines in medical labs and scientific institutions has become pressing.In particular,the advent of SARS-CoV-2 as a global threat has catapulted the need for robust biosecurity measures into the forefront of scientific discourse.The potential for unintentional biological outbreaks and the malicious exploitation of biological agents by terrorist organizations have intensified the research focus on biosafety by underlining the urgent need to strengthen biosafety and biosecurity measures in laboratories.1 This letter aims to explore the biosafety and biosecurity challenges encountered within the Iraqi Kurdistan region. 展开更多
关键词 measures intensified evolve
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