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H pylori infection and other risk factors associated with peptic ulcers in Turkish patients: A retrospective study 被引量:11
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作者 Barik A Salih M Fatih Abasiyanik +1 位作者 Nizamettin Bayyurt Ersan Sander 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第23期3245-3248,共4页
AIM: To identify and evaluate the relative impact of H pylori infection and other risk factors on the occurrence of gastric ulcer (GU), duodenal ulcer (DU) and gastritis in Turkish patients. METHODS: A total of 4471 p... AIM: To identify and evaluate the relative impact of H pylori infection and other risk factors on the occurrence of gastric ulcer (GU), duodenal ulcer (DU) and gastritis in Turkish patients. METHODS: A total of 4471 patients (48.3% female) out of 4863 attended the Samatya hospital in Istanbul (June 1999 - October 2003) were included. The records of H pylori status (CLO-test), endoscopic f indings of GU, DU and gastritis, personal habits (smoking, alcohol intake) and medication [non-steroidal anti-inflammatory drugs (NSAIDs), aspirin intake] were analyzed using multi-way frequency analysis. RESULTS: We have found that GU in the presence of H pylori had significant association with aspirin (P = 0.0001), alcohol (P = 0.0090) and NSAIDs (P = 0.0372). DU on the other hand had significant association with aspirin/ smoking/NSAIDs (P = 0.0259), aspirin/alcohol (P = 0.0002) and aspirin/smoking (P = 0.0233), also in the presence of H pylori. In the absence of H pylori GU had significant association with alcohol/NSAIDs (P = 0.0431), and NSAIDs (P = 0.0436). While DU in the absence of H pylori had significant association with smoking/alcohol/ NSAIDs (P = 0.0013), aspirin/NSAIDs (P = 0.0334), aspirin/alcohol (P = 0.0360). CONCLUSION: In the presence of H pylori, aspirin, alcohol and NSAIDs intake act as an independent risk factors that had an augmenting impact on the occurrence of GU and only together on the occurrence of DU in Turkish patients. 展开更多
关键词 H pylori Risk factors Peptic ulcer disease Duodenal ulcer Gastric ulcer GASTRITIS
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Antibacterial Activities of <i>Psidium guajava</i>(Guava) and <i>Velvet tamarin</i>(Icheku) Local Chewing Sticks on <i>Streptococcus mutans</i>Isolated from Human Mouth 被引量:1
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作者 I. A. Ojiuko C. O. Anyamene +2 位作者 C. U. Ezebialu A. P. Unamadu C. S. Alisigwe 《Open Journal of Medical Microbiology》 2021年第2期80-90,共11页
<span style="font-family:Verdana;">Globally dental diseases are mainly caused by</span><i><span style="font-family:Verdana;"> Streptococcus mutans</span></i><... <span style="font-family:Verdana;">Globally dental diseases are mainly caused by</span><i><span style="font-family:Verdana;"> Streptococcus mutans</span></i><span style="font-family:""><span style="font-family:Verdana;">, it is one of the leading causative agents of dental caries worldwide, because of its resistance to </span><span><span style="font-family:Verdana;">conventional antibacterial agents, alternative therapies are used to control resistance of oral pathogens. This research was done to determine the antibacterial activities of </span><i><span style="font-family:Verdana;">Psidium guajava</span></i><span style="font-family:Verdana;"> (guava) and </span><i><span style="font-family:Verdana;">Velvet tamarin</span></i><span style="font-family:Verdana;"> (Icheku) chewing sticks on </span><i><span style="font-family:Verdana;">Streptococcus mutans</span></i><span style="font-family:Verdana;"> isolated from the oral cavity. The study was conducted in Owerri Imo State Nigeria during November-December</span></span><span style="font-family:Verdana;"> period. Phytochemical analysis of the plant extracts was done using appropriate techniques. The procedure used for antimicrobial susceptibility test was disk diffusion method. Serial dilutions of</span><i><span style="font-family:Verdana;"> Psidium guajava</span></i><span style="font-family:Verdana;"> (guava) and </span><i><span style="font-family:Verdana;">Velvet tamarind</span></i><span style="font-family:Verdana;"> (Icheku) extracts were prepared, Muller-Hinton media was used to put together the extract of serial dilutions of </span><i><span style="font-family:Verdana;">Psidium guajava</span></i><span style="font-family:Verdana;"> (guava) and </span><i><span style="font-family:Verdana;">Velvet tamarin</span></i><span style="font-family:Verdana;"> (Icheku) and </span></span><span style="font-family:Verdana;">a </span><span style="font-family:Verdana;">microbiological procedure w</span><span style="font-family:Verdana;">ere</span><span style="font-family:Verdana;"> used for visually determining the minimum inhibitory concentration as well as minimum bactericidal concentration. Phytochemical evaluation of the plants</span><span style="font-family:Verdana;">’</span><span style="font-family:""><span style="font-family:Verdana;"> extracts revealed that it contains saponins, tannins, alkaloid, steriods, glycosides and phenol. The results obtained from the antibacterial susceptibility testing of the extracts against </span><i><span style="font-family:Verdana;">Streptococcus mutans</span></i><span style="font-family:Verdana;"> showed that the zones of inhibition recorded ranged from 18</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">mm to 27</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">mm. Ethanol (Soxhlet) extract of I</span><span style="font-family:Verdana;">cheku twig showed no zone of inhibition on the isolated organism. The</span><span style="font-family:Verdana;"> ethanol (soxhlet) extract of the individual </span><i><span style="font-family:Verdana;">Psidium guajava</span></i><span style="font-family:Verdana;"> (guava) and </span><i><span style="font-family:Verdana;">Velvet tamarin</span></i><span style="font-family:Verdana;"> (Icheku) has a better antibacterial effect when compared to their aqueous extracts and combined forms. </span><i><span style="font-family:Verdana;">Psidium guajava</span></i><span style="font-family:Verdana;"> (Guava) and </span><i><span style="font-family:Verdana;">Velvet tamarin</span></i><span style="font-family:Verdana;"> (Icheku) twigs are made up of composite that </span></span><span style="font-family:Verdana;">is</span><span style="font-family:""><span style="font-family:Verdana;"> active against </span><i><span style="font-family:Verdana;">S. mutans</span></i><span style="font-family:Verdana;"> and can be used in oral hygiene. There is </span></span><span style="font-family:Verdana;">a </span><span style="font-family:Verdana;">need for further investigation on the plant extracts as the rural poor make use of it because it is cheap, readily available and the rich also use it once they are in the village mostly in Eastern Nigeria. Similarly chewing sticks has been reported to be practiced by 90 of rural population in Nigeria</span><span style="font-family:Verdana;">. 展开更多
关键词 Antibacterial Activity Chewing Sticks Psidium guajava (Guava) Velvet tamarin (Icheku) Streptococcus mutans
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Effect of Biochar Application on Soil Carbon Fluxes from Sequential Dry and Wet Cultivation Systems
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作者 Mahmudul Islam Piash Md. Faruque Hossain +2 位作者 Ihuoma N. Anyanwu Shamim Al Mamun Zakia Parveen 《American Journal of Climate Change》 2018年第1期40-53,共14页
Application of biochar has been highly credited for its potential to sequester carbon and GHG mitigation from tropical agro-ecosystems. However, experiments show inconsistent results depending on soil and biochar type... Application of biochar has been highly credited for its potential to sequester carbon and GHG mitigation from tropical agro-ecosystems. However, experiments show inconsistent results depending on soil and biochar type, cultivation system, climatic condition and the type of evolved GHGs. This study emphasized on the effect of biochar on carbon emission trends from a sequential dry and wet cultivation system of Bangladesh. An incubation study was conducted with two contrasting soils and eight different treatments viz. control, only fertilizer, three different biochars (10 t·ha-1) with and without recommended fertilizer dose. Results revealed the fact that, emission of carbon was substantially higher from Sara soil than Kalma soil. Biochar treatments did not have any easing effect on CO2 emission at field condition;rather, increased in most of the cases. However, emission was significantly (P 2. Biochar application was ineffective to control CH4 and CO release to atmosphere and submergence further intensified their emission significantly. The overall results indicate that applied biochars have negligible effect on carbon emission except for reducing CO2 from submerged soils. 展开更多
关键词 GREENHOUSE Gases Carbon EMISSION CO2 CH4 CO EMISSION from SUBMERGENCE
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根除幽门螺杆菌对胃组织学严重程度的影响:一项随访研究
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作者 Salih B.A. Abasiyanik M.F. +1 位作者 Saribasak H. 赵天智 《世界核心医学期刊文摘(胃肠病学分册)》 2006年第2期11-11,共1页
Helicobacter pylori genetic diversity and geographic distribution affect the severity of gastric histology; while eradication heals gastritis, the improvement of atrophy and intestinal metaplasia (IM) is still controv... Helicobacter pylori genetic diversity and geographic distribution affect the severity of gastric histology; while eradication heals gastritis, the improvement of atrophy and intestinal metaplasia (IM) is still controversial. We investigated whether H. pylori infection and genotypes (cagA- vacA) influence the histological changes and whether eradication resolves these changes. Twenty- one patients (11 duodenal ulcer, 2 gastric ulcer, 8 gastritis) received treatment. Biopsies for CLO, PCR, histology, and culture were collected before and at 1 and 12 months after treatment, and serum samples at 0, 1, 2, 6, and 12 months. H. pylori eradication was achieved in 71% of the patients. Histological scores for H. pylori densities were significantly higher in the antrum and incisura angularis. Scores for mononuclear cell and neutrophil infiltration were significantly higher in regions with a high H. pylori density and improved progressively after eradication. Eight patients with atrophy including five with IM showed no significant changes 12 months after eradication. The cagA gene, detected in 13 (62% ), the vacA- s1a gene, in 20 (95% ), and the vacA- m1 gene, in 12 (57% ) of 21 patients were significantly associated with duodenal ulcer. A gradual decline in antibody titer reached an average of 67% 12 months after eradication. H. pylori infection and the associated genotypes (cagA of Western type) affect the severity of the gastric histology (mild forms of atrophy and IM) and the disease outcome. Eradication of H. pyloriresulted in healing of gastritis, but with no significant improvement in atrophy or IM. 展开更多
关键词 胃组织 随访研究 肠化生 VACA 胃黏膜萎缩 中性粒细胞浸润 组织学检查 组织学评分 细胞培养
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Impact of Plasmodium falciparum infection on some haematological parameters in a malaria endemic population, Southeastern Nigeria
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作者 Ozioma Prisca Irole-Eze Onyinye Mkpola Ukpai +2 位作者 Ebube Charles Amaechi Blessing Uzoamaka Ejike Chidiogo Comfort Nwadike 《Journal of Coastal Life Medicine》 CAS 2017年第12期547-549,共3页
Objective: To compare changes in some haematological parameters among malaria positive and negative subjects in a malaria endemic community, Southeastern Nigeria. Methods: Haematological parameters of 443 subjects inc... Objective: To compare changes in some haematological parameters among malaria positive and negative subjects in a malaria endemic community, Southeastern Nigeria. Methods: Haematological parameters of 443 subjects including 234 confirmed malaria infected and 209 non-malaria infected patients who attended various hospitals in selected communities of Ezinihite L.G.A, Southeastern Nigeria between January and June 2014 were evaluated. Results: Total white blood count and two of its differentials (lymphocytes and granulocytes), red blood cell and platelet counts were significantly lower among malaria-infected subjects compared to the non-infected subjects (P < 0.05) Conclusions: Haematological parameters of malaria infected subjects were significantly lower than that of uninfected individuals. This present research adds to the fact that haematological parameters is a good and reliable indicator for the early and prompt diagnosis of malaria in patients. 展开更多
关键词 Haematological parameters PLASMODIUM FALCIPARUM ANAEMIA Southeastern NIGERIA
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