BACKGROUND The detection rate of depression among university students has been increasing in recent years,becoming one of the main psychological diseases that endangers their physical and mental health.According to st...BACKGROUND The detection rate of depression among university students has been increasing in recent years,becoming one of the main psychological diseases that endangers their physical and mental health.According to statistics,self-harm and suicide,for which there is no effective intervention,are the second leading causes of death.AIM To explore the relationship between different elements and levels of physical activity and college students’depression-symptom-specific working memory indicators.METHODS Of 143 college students were analyzed using the Beck Depression Self-Rating Scale,the Physical Activity Rating Scale,and the Working Memory Task.RESULTS There was a significant difference between college students with depressive symptoms and healthy college students in completing verbal and spatial working memory(SWM)tasks correctly(all P<0.01).Physical Activity Scale-3 scores were significantly and positively correlated with the correct rate of the verbal working memory task(r=0.166)and the correct rate of the SWM task(r=0.210)(all P<0.05).There were significant differences in the correct rates of verbal and SWM tasks according to different exercise intensities(all P<0.05)and different exercise durations(all P<0.05),and no significant differences in the correct rates of verbal and SWM tasks by exercise frequency(all P>0.05).CONCLUSION An increase in physical exercise among college students,particularly medium-and high-intensity exercise and exercise of 30 min or more,can improve the correct rate of completing working memory tasks.展开更多
Attempts have been made to use cell transplantation and biomaterials to promote cell proliferation,differentiation,migration,and survival,as well as angiogenesis,in the context of brain injury.However,whether bioactiv...Attempts have been made to use cell transplantation and biomaterials to promote cell proliferation,differentiation,migration,and survival,as well as angiogenesis,in the context of brain injury.However,whether bioactive materials can repair the damage caused by ischemic stroke by activating endogenous neurogenesis and angiogenesis is still unknown.In this study,we applied chitosan gel loaded with basic fibroblast growth factor to the stroke cavity 7 days after ischemic stroke in rats.The gel slowly released basic fibroblast growth factor,which improved the local microenvironment,activated endogenous neural stem/progenitor cells,and recruited these cells to migrate toward the penumbra and stroke cavity and subsequently differentiate into neurons,while enhancing angiogenesis in the penumbra and stroke cavity and ultimately leading to partial functional recovery.This study revealed the mechanism by which bioactive materials repair ischemic strokes,thus providing a new strategy for the clinical application of bioactive materials in the treatment of ischemic stroke.展开更多
BACKGROUND Depression is a common mental disorder among college students.The main symptoms include being persistent low mood,sad emotional experiences,lack of pleasure,listlessness,and impaired cognitive function acco...BACKGROUND Depression is a common mental disorder among college students.The main symptoms include being persistent low mood,sad emotional experiences,lack of pleasure,listlessness,and impaired cognitive function accompanied by tendencies of self-harm and suicide.AIM To clarify the pathways and effects of the behavioral activation system between physical activity and depressive symptoms in college students with depressive symptoms.METHODS This cross-sectional research screened 3047 college students.Of these,472 had depressive symptoms,with a depression detection rate of 15.49%.Furthermore,442 college students with depressive symptoms were analyzed.A one-way analysis of variance and Pearson’s correlation,linear regression,and structural equation modeling analyses were used to explore the correlations and pathways of the interactions between the variables.RESULTS Depressive symptoms were significantly negatively correlated with physical activity(r=-0.175,P<0.001),the behavioral activation system(r=-0.197,P<0.001),and drive(r=-0.113,P=0.017).Furthermore,it was negatively correlated with fun-seeking(FS)(r=-0.055,P=0.251);however,it was not significant.Physical activity was significantly positively correlated with reward responsiveness(RR)(r=0.141,P=0.003)and drive(r=0.124,P=0.009)and not significantly positively correlated with FS(r=0.090,P=0.058).The mediating effect of RR between physical activity and depressive symptoms was significant[B=-0.025,95%confidence interval(95%CI):-0.051 to-0.008,P=0.001].The direct and total effects of physical activity on depressive symptoms and were significant(B=-0.150,95%CI:-0.233 to-0.073,P<0.001;B=-0.175,95%CI:-0.260 to-0.099,P<0.001),respectively.CONCLUSION As physical activity levels increased,depression scores among college students decreased.The mediating effect of RR between physical activity and depressive symptoms was significant.Therefore,colleges and universities should encourage college students with depression to increase their physical activity and improve their behavioral activation system.Particular attention should be paid to RR,which may reduce the prevalence of depressive symptoms.展开更多
Parkinson’s disease is chara cterized by the loss of dopaminergic neurons in the substantia nigra pars com pacta,and although restoring striatal dopamine levels may improve symptoms,no treatment can cure or reve rse ...Parkinson’s disease is chara cterized by the loss of dopaminergic neurons in the substantia nigra pars com pacta,and although restoring striatal dopamine levels may improve symptoms,no treatment can cure or reve rse the disease itself.Stem cell therapy has a regenerative effect and is being actively studied as a candidate for the treatment of Parkinson’s disease.Mesenchymal stem cells are considered a promising option due to fewer ethical concerns,a lower risk of immune rejection,and a lower risk of teratogenicity.We performed a meta-analysis to evaluate the therapeutic effects of mesenchymal stem cells and their derivatives on motor function,memory,and preservation of dopamine rgic neurons in a Parkinson’s disease animal model.We searched bibliographic databases(PubMed/MEDLINE,Embase,CENTRAL,Scopus,and Web of Science)to identify articles and included only pee r-reviewed in vivo interve ntional animal studies published in any language through J une 28,2023.The study utilized the random-effect model to estimate the 95%confidence intervals(CI)of the standard mean differences(SMD)between the treatment and control groups.We use the systematic review center for laboratory animal expe rimentation’s risk of bias tool and the collaborative approach to meta-analysis and review of animal studies checklist for study quality assessment.A total of 33studies with data from 840 Parkinson’s disease model animals were included in the meta-analysis.Treatment with mesenchymal stem cells significantly improved motor function as assessed by the amphetamine-induced rotational test.Among the stem cell types,the bone marrow MSCs with neurotrophic factor group showed la rgest effect size(SMD[95%CI]=-6.21[-9.50 to-2.93],P=0.0001,I^(2)=0.0%).The stem cell treatment group had significantly more tyrosine hydroxylase positive dopamine rgic neurons in the striatum([95%CI]=1.04[0.59 to 1.49],P=0.0001,I^(2)=65.1%)and substantia nigra(SMD[95%CI]=1.38[0.89 to 1.87],P=0.0001,I^(2)=75.3%),indicating a protective effect on dopaminergic neurons.Subgroup analysis of the amphetamine-induced rotation test showed a significant reduction only in the intracranial-striatum route(SMD[95%CI]=-2.59[-3.25 to-1.94],P=0.0001,I^(2)=74.4%).The memory test showed significant improvement only in the intravenous route(SMD[95%CI]=4.80[1.84 to 7.76],P=0.027,I^(2)=79.6%).Mesenchymal stem cells have been shown to positively impact motor function and memory function and protect dopaminergic neurons in preclinical models of Parkinson’s disease.Further research is required to determine the optimal stem cell types,modifications,transplanted cell numbe rs,and delivery methods for these protocols.展开更多
Background:One of the pathological hallmarks distinguishing Alzheimer’s disease from other dementias is the accumulation of amyloid beta(Aβ).Higher physical activity is associated with decreased dementia risk,and on...Background:One of the pathological hallmarks distinguishing Alzheimer’s disease from other dementias is the accumulation of amyloid beta(Aβ).Higher physical activity is associated with decreased dementia risk,and one potential path could be through Aβlevels modulation.We aimed to explore the relationship between physical activity and Aβin middle-aged and older adults.Methods:A systematic search of PubMed,Web of Science,PsycINFO,Cochrane Central Register of Controlled Trials,and SPORTDiscus was performed from inception to April 28,2022.Studies were eligible if they included physical activity and Aβdata in adults aged 45 years or older.Multi-level metaanalyses of intervention and observational studies were performed to examine the role of physical activity in modulating Aβlevels.Results:In total,37 articles were included(8 randomized controlled trials,3 non-randomized controlled trials,4 prospective longitudinal studies,and 22 cross-sectional studies).The overall effect size of physical activity interventions on changes in blood Aβwas medium(pooled standardized mean difference=-0.69,95%confidence interval(95%CI):-1.41 to 0.03;I^(2)=74.6%).However,these results were not statistically significant,and there were not enough studies to explore the effects of physical activity on cerebrospinal fluid(CSF)and brain Aβ.Data from observational studies were examined based on measurements of Aβin the brain using positron emission tomography scans,CSF,and blood.Higher physical activity was positively associated with Aβonly in the CSF(Estimate r=0.12;95%CI:0.05-0.18;I^(2)=38.00%).Conclusion:Physical activity might moderately reduce blood Aβin middle-aged and older adults.However,results were only near statistical significance and might be interpreted with caution given the methodological limitations observed in some of the included studies.In observational studies,higher levels of physical activity were positively associated with Aβonly in CSF.Therefore,further research is needed to understand the modulating role of physical activity in the brain,CSF,and blood Aβ,as well as its implication for cognitive health.展开更多
The problems faced the policymakers of the present universities in physical education are how to break away from the traditional models of training,how to set up new systems,how to exploit resources in community and u...The problems faced the policymakers of the present universities in physical education are how to break away from the traditional models of training,how to set up new systems,how to exploit resources in community and university for physical education,how to make the exercise courses,capacity and time for the inhabitsnts more scientific and reasonable and how to constantly satisfy most exercisers.This paper,by analysing the present situation of university physical education and social physical education,exploits their organic combination,to efficiently train high-qualified and all-round-way-developed talents.展开更多
Background: Identifying factors associated with physical activity(PA) is useful in planning interventions and policies. The aim of this study was to identify sociodemographic, biological, and psychosocial factors asso...Background: Identifying factors associated with physical activity(PA) is useful in planning interventions and policies. The aim of this study was to identify sociodemographic, biological, and psychosocial factors associated with PA performed in school settings.Methods: Data collected for the present study included gender, age, socioeconomic status, body fat percentage, aerobic fitness, self-efficacy, attitudes,peer and parental support, and perception of school environment. Dependent variables were light-intensity PA(LPA) and moderate-to-vigorousintensity PA(MVPA) performed during school time, recesses, and physical education(PE) classes. Multiple regression analyses were performed.Results: Participating adolescents(n = 567, 53% female, 12.9 ± 5.3 years) spent 5% of school time in MVPA and 27% in LPA, 15% of recesses in MVPA and 44% in LPA, and 16% of PE classes in MVPA and 41% in LPA. Boys engaged in more MVPA in all categories. Age was inversely related with MVPA and LPA in all periods, whereas body fat percentage was inversely related with MVPA in school time and PE classes. Attitude was inversely related with MVPA in all periods and with LPA in recesses. Considering PA to be good and enjoyable was positively associated with MVPA in school time.Conclusion: Adolescents spent little time in PA during school. Future interventions should implement enjoyable activities at school.展开更多
Purpose:Given the unique characteristics of physical education(PE) teaching in K-12education,PE teachers' information behaviors deserve special attention.This article reports a survey study of PE teachers' inf...Purpose:Given the unique characteristics of physical education(PE) teaching in K-12education,PE teachers' information behaviors deserve special attention.This article reports a survey study of PE teachers' information behaviors,covering information literacy skills and behaviors of information seeking and information use.Design/methodology/approach:A questionnaire survey was conducted of K-12 PE teachers in the Tianjin municipal region of China,with a response rate of 61.9%.Findings:PE teachers lack skills with information retrieval systems in general.The Internet continues to be their primary information source,and they rely more on personal collection and colleagues than the school library for teaching materials.They rarely develop a searching strategy,employ querying tactics,or use advanced search functions,and they tend to be content with finding a few relevant articles.Research limitations:The survey is limited to the Tianjin municipal region in scope.Though attempting to reach 210 participants from 40 schools,it yielded only 130 valid responses.A larger survey covering more regions and with greater responses may be useful.Practical implications:Insights from this study inform the educational and on-job training of K-12 PE teachers to improve their information literacy skills.Originality/value:Little research exists on PE teachers' behaviors of information seeking.This study bridges the gap and enriches our understanding of K-12 teachers' information behaviors.展开更多
At present,physical education is listed as the key teaching.This paper introduces the importance of physical education in Colleges and universities,analyzes the current situation of College Physical Education and expl...At present,physical education is listed as the key teaching.This paper introduces the importance of physical education in Colleges and universities,analyzes the current situation of College Physical Education and explores the improvement strategies of College Physical Education at this stage.展开更多
Objective This study initially validates the Chinese version of the Physical Activity Questionnaire for Older Children(PAQ-C), which has been identified as a potentially valid instrument to assess moderate-to-vigorous...Objective This study initially validates the Chinese version of the Physical Activity Questionnaire for Older Children(PAQ-C), which has been identified as a potentially valid instrument to assess moderate-to-vigorous physical activity(MVPA) in children among diverse racial groups. Methods The psychometric properties of the PAQ-C with 742 Hong Kong Chinese children were assessed with the scale's internal consistency, reliability, test-retest reliability, confirmatory factory analysis(CFA) in the overall sample, and multistep invariance tests across gender groups as well as convergent validity with body mass index(BMI), and an accelerometry-based MVPA. Results The Cronbach alpha coefficient(α=0.79), composite reliability value(ρ=0.81), and the intraclass correlation coefficient(α=0.82) indicate the satisfactory reliability of the PAQ-C score. The CFA indicated data fit a single factor model, suggesting that the PAQ-C measures only one construct, on MVPA over the previous 7 days. The multiple-group CFAs suggested that the factor loadings and variances and covariances of the PAQ-C measurement model were invariant across gender groups. The PAQ-C score was related to accelerometry-based MVPA(r=0.33) and inversely related to BMI(r=-0.18). Conclusion This study demonstrates the reliability and validity of the PAQ-C in Chinese children.展开更多
Background: Although emerging research is demonstrating the potential health impact of exergaming,investigations have primarily been conducted in laboratory settings among small samples with short-term interventions.I...Background: Although emerging research is demonstrating the potential health impact of exergaming,investigations have primarily been conducted in laboratory settings among small samples with short-term interventions.Information on the effectiveness of exergaming in underserved children's objective physical activity(PA) in population-based settings is also scarce.Moreover,most empirical studies have only included 1 type of exergame in the intervention.Therefore,this study's purpose was to investigate the long-term impact of a multigame exergaming intervention among underserved children integrated within school curricula.Specifically,this study examined the effect of exergaming on children's accelerometer-determined sedentary behavior(SB),light PA,moderate-to-vigorous PA(MVPA),and energy expenditure(EE) over 2 years as compared with regular physical education(PE) classes.Methods: A total of 261 second-and third-grade children(134 girls,127 boys; mean age 8.27 years) were recruited from 2 Texas elementary schools.Children's pre-test 3-day SB,light PA,MVPA,and EE at school were assessed in the fall of 2012.Participants were assigned to 1 of 2groups:(1) exergaming/PE group(125 min weekly of exergaming-based PA program) and (2) comparison group(125 min weekly of PE).PA(SB,light PA,and MVPA) and EE outcome variables were assessed again in 2013(post-test) and 2014(follow-up).Results: Significant time effects were observed for SB(F(1,162)=25.0,p<0.01,η~2= 0.14),light PA(F(1,162)=9.6,p<0.01,η~2= 0.06),and MVPA(F(1,162)=6.2,p=0.01,η~2= 0.04) but not for EE(F(1,162)=0.63,p>0.05,η~2= 0.004).Subsequent pairwise comparisons revealed significant increases from pre-to post-test for light PA(p<0.01),MVPA(p<0.01),and EE(p=0.02) with no changes in SB(p>0.05).Conversely,significant decreases occurred in light PA(p<0.01) from post-test to follow-up with no differences seen in MVPA(p=0.08) and EE(p=0.06) over the same time period.A significant increase was seen,however,for SB from post-test to follow-up.Conclusion: Exergaming PE can have the same positive effect on children's light PA,MVPA,and EE as regular PE.More research is necessary to discern how to promote long-term PA participation after conclusion of the intervention.展开更多
Objectives:Adolescents using active transport(AT)to school have higher levels of physical activity(PA)compared with motorized transport(MT)users.This study compared school day and weekend day PA in adolescents using A...Objectives:Adolescents using active transport(AT)to school have higher levels of physical activity(PA)compared with motorized transport(MT)users.This study compared school day and weekend day PA in adolescents using AT,MT,or combined AT and MT(AT + MT)to travel to school.Methods:Adolescents(n= 314;age:14.7±1.4 years;32.8% boys)from Dunedin(New Zealand)wore an accelerometer for 7 days and completed a self-reported survey regarding mode of transport to school(73 AT,56 AT + MT,and 185 MT).Data were analyzed using t tests,analysis of variance,and χ2 tests.Results:Although the proportion of adolescents meeting PA guidelines significantly differed among transport groups(AT,47.9%;AT + MT,46.4%;MT,33.5%;p=0.048;overall,39.2%),the observed differences were due mainly to girls.Compared with MT,AT and AT+MT engaged in more moderate-to-vigorous PA(MVPA)per day(AT:61.2 ± 23.2 min;AT+MT:59.6 ± 21.7 min;MT:52.5 ± 19.6 min;p = 0.004;p<0.001,adjusted for gender),per school day and before school.Immediately after school(15:00-16:00),AT engaged in significantly more MVPA compared with AT + MT and MT.No differences in MVPA between the groups were observed in the late afternoon/early evening period during school days or on weekend days.Conclusion:Compared with MT users,adolescent girls using AT or AT + MT accumulated more MVPA during school commute time.AT + MT to school is also a plausible way to increase adolescent girls’ PA when AT only is not feasible.展开更多
Background: Physical activity participation(PAP) has been proven to improve health and promote optimal growth among adolescents. However,most adolescents do not meet the current physical activity(PA) recommendations i...Background: Physical activity participation(PAP) has been proven to improve health and promote optimal growth among adolescents. However,most adolescents do not meet the current physical activity(PA) recommendations in Turkey. The role of the social environment and social factors on PAP is being increasingly recognized. Although social capital(SC) indicators have been examined in high-income countries, there are few studies on developing countries. The aim of this study was to examine the relationship between SC indicators and PAP among Turkish adolescents.Methods: A survey was conducted among 19 high schools in 4 different cities in Turkey in 2016. A total of 506 female and 729 male high school students participated in this study. The dependent variable was overall PAP, which was measured using the short form of the International Physical Activity Questionnaire. The independent variables included self-perceived family, neighborhood, and school SC. Self-rated health and obesity status, measured by body mass index, were other study covariates in multiple binary logistic regression models. Chi-square tests were used to assess the differences between genders.Results: PAP levels were significantly different between males and females. A higher percentage of males reported PAP(77.4%) compared to females(51.0%). Among males, teacher–student interpersonal trust and informal social control were inversely associated with PAP, while high students interpersonal trust was positively associated with increased odds of PAP. For females, students interpersonal trust was inversely associated with PAP.Conclusion: Various SC indicators are associated with PAP for males and females. These associations are different from findings of studies conducted in developed countries. Therefore, health-promotion interventions and policies should consider gender and different social agents on the social and cultural background to improve PAP among Turkish adolescents.展开更多
Background:This study systematically synthesized and quantified the relationship linking state laws governing school physical education(PE)to PE attendance and physical activity(PA)in class and throughout the day and ...Background:This study systematically synthesized and quantified the relationship linking state laws governing school physical education(PE)to PE attendance and physical activity(PA)in class and throughout the day and week among students in the USA.Methods:A keyword search was performed in PubMed,Web of Science,Cumulative Index to Nursing and Allied Health Literature(CINAHL),Academic Search Complete,and EconLit.Meta-analyses were performed to estimate the effects of state PE laws.Results:A total of 17 studies were included in the review,and five contributed to the meta-analyses.A total of 8 studies used nationally representative school-or student-level data,three focused on multiple states,and the remaining six examined the PE laws of a single state.The presence and strength of state PE laws were positively associated with PE attendance and the frequency and duration of PA during PE classes and throughout the school day.Compared to those residing in states with weak or no PE laws,students in states with strong PE laws had an additional 0.2 days(95%confidence interval(95%CI):0.10.4)of PE attendance per week and spent an additional 33.9 min(95%CI:22.745.0)participating PE classes per week.State PE laws affected girls’PA more than boys’.Different aspects of state PE laws tended to affect students’PE attendance differently.Disparities in the implementation of state PE laws existed across schools.Conclusion:Future studies should adopt objective measures on PE and PA participation and examine the roles schools and districts play in mediating the effect of state PE laws on students’PE attendance and PA.展开更多
Purpose: The purpose of the present study was to determine if there were any differences in various aspects of physical activity such as energy expenditure, intensity, and type of activity between normal-weight and ov...Purpose: The purpose of the present study was to determine if there were any differences in various aspects of physical activity such as energy expenditure, intensity, and type of activity between normal-weight and overweight boys.Methods: Children aged 9—12 years were recruited from 2 elementary schools located in different urban districts in Republic of Korea. The present study included 45 Korean boys, of which 19 were normal-weight and 26 were overweight. Daily physical activity was estimated over the same 1-week study period under free-living conditions using the doubly labeled water(DLW) method and a tri-axial accelerometer. Resting metabolic rate(RMR) was measured using the Douglas bag method and open-circuit indirect calorimetry. We calculated the physical activity level(PAL) as the total energy expenditure(TEE)/RMR.Results: PAL was not significantly different between the groups. In the accelerometer data, time spent in locomotive moderate-to-vigorous physical activity(MVPA) was significantly lower in overweight boys than in normal-weight subjects, whereas other variables including non-locomotive activity did not differ between groups. In addition, among all participants, time spent in total locomotive activity was significantly associated with PAL. Time spent in locomotive MVPA was significantly associated with PAL.Conclusion: Overweight boys may be less physically active based on locomotive MVPA, which was positively related with PAL. Our findings suggest that the contribution of locomotive MVPA to the increase in PAL was relatively significant.展开更多
文摘BACKGROUND The detection rate of depression among university students has been increasing in recent years,becoming one of the main psychological diseases that endangers their physical and mental health.According to statistics,self-harm and suicide,for which there is no effective intervention,are the second leading causes of death.AIM To explore the relationship between different elements and levels of physical activity and college students’depression-symptom-specific working memory indicators.METHODS Of 143 college students were analyzed using the Beck Depression Self-Rating Scale,the Physical Activity Rating Scale,and the Working Memory Task.RESULTS There was a significant difference between college students with depressive symptoms and healthy college students in completing verbal and spatial working memory(SWM)tasks correctly(all P<0.01).Physical Activity Scale-3 scores were significantly and positively correlated with the correct rate of the verbal working memory task(r=0.166)and the correct rate of the SWM task(r=0.210)(all P<0.05).There were significant differences in the correct rates of verbal and SWM tasks according to different exercise intensities(all P<0.05)and different exercise durations(all P<0.05),and no significant differences in the correct rates of verbal and SWM tasks by exercise frequency(all P>0.05).CONCLUSION An increase in physical exercise among college students,particularly medium-and high-intensity exercise and exercise of 30 min or more,can improve the correct rate of completing working memory tasks.
基金supported by the National Natural Science Foundation of China,Nos.81941011(to XL),31771053(to HD),31730030(to XL),31971279(to ZY),31900749(to PH),31650001(to XL),31320103903(to XL),31670988(to ZY)the Natural Science Foundation of Beijing,Nos.7222004(to HD)+1 种基金a grant from Ministry of Science and Technology of China,Nos.2017YFC1104002(to ZY),2017YFC1104001(to XL)a grant from Beihang University,No.JKF-YG-22-B001(to FH)。
文摘Attempts have been made to use cell transplantation and biomaterials to promote cell proliferation,differentiation,migration,and survival,as well as angiogenesis,in the context of brain injury.However,whether bioactive materials can repair the damage caused by ischemic stroke by activating endogenous neurogenesis and angiogenesis is still unknown.In this study,we applied chitosan gel loaded with basic fibroblast growth factor to the stroke cavity 7 days after ischemic stroke in rats.The gel slowly released basic fibroblast growth factor,which improved the local microenvironment,activated endogenous neural stem/progenitor cells,and recruited these cells to migrate toward the penumbra and stroke cavity and subsequently differentiate into neurons,while enhancing angiogenesis in the penumbra and stroke cavity and ultimately leading to partial functional recovery.This study revealed the mechanism by which bioactive materials repair ischemic strokes,thus providing a new strategy for the clinical application of bioactive materials in the treatment of ischemic stroke.
基金Supported by Shanghai Key Lab of Human Performance(Shanghai University of sport),No.11DZ2261100.
文摘BACKGROUND Depression is a common mental disorder among college students.The main symptoms include being persistent low mood,sad emotional experiences,lack of pleasure,listlessness,and impaired cognitive function accompanied by tendencies of self-harm and suicide.AIM To clarify the pathways and effects of the behavioral activation system between physical activity and depressive symptoms in college students with depressive symptoms.METHODS This cross-sectional research screened 3047 college students.Of these,472 had depressive symptoms,with a depression detection rate of 15.49%.Furthermore,442 college students with depressive symptoms were analyzed.A one-way analysis of variance and Pearson’s correlation,linear regression,and structural equation modeling analyses were used to explore the correlations and pathways of the interactions between the variables.RESULTS Depressive symptoms were significantly negatively correlated with physical activity(r=-0.175,P<0.001),the behavioral activation system(r=-0.197,P<0.001),and drive(r=-0.113,P=0.017).Furthermore,it was negatively correlated with fun-seeking(FS)(r=-0.055,P=0.251);however,it was not significant.Physical activity was significantly positively correlated with reward responsiveness(RR)(r=0.141,P=0.003)and drive(r=0.124,P=0.009)and not significantly positively correlated with FS(r=0.090,P=0.058).The mediating effect of RR between physical activity and depressive symptoms was significant[B=-0.025,95%confidence interval(95%CI):-0.051 to-0.008,P=0.001].The direct and total effects of physical activity on depressive symptoms and were significant(B=-0.150,95%CI:-0.233 to-0.073,P<0.001;B=-0.175,95%CI:-0.260 to-0.099,P<0.001),respectively.CONCLUSION As physical activity levels increased,depression scores among college students decreased.The mediating effect of RR between physical activity and depressive symptoms was significant.Therefore,colleges and universities should encourage college students with depression to increase their physical activity and improve their behavioral activation system.Particular attention should be paid to RR,which may reduce the prevalence of depressive symptoms.
文摘Parkinson’s disease is chara cterized by the loss of dopaminergic neurons in the substantia nigra pars com pacta,and although restoring striatal dopamine levels may improve symptoms,no treatment can cure or reve rse the disease itself.Stem cell therapy has a regenerative effect and is being actively studied as a candidate for the treatment of Parkinson’s disease.Mesenchymal stem cells are considered a promising option due to fewer ethical concerns,a lower risk of immune rejection,and a lower risk of teratogenicity.We performed a meta-analysis to evaluate the therapeutic effects of mesenchymal stem cells and their derivatives on motor function,memory,and preservation of dopamine rgic neurons in a Parkinson’s disease animal model.We searched bibliographic databases(PubMed/MEDLINE,Embase,CENTRAL,Scopus,and Web of Science)to identify articles and included only pee r-reviewed in vivo interve ntional animal studies published in any language through J une 28,2023.The study utilized the random-effect model to estimate the 95%confidence intervals(CI)of the standard mean differences(SMD)between the treatment and control groups.We use the systematic review center for laboratory animal expe rimentation’s risk of bias tool and the collaborative approach to meta-analysis and review of animal studies checklist for study quality assessment.A total of 33studies with data from 840 Parkinson’s disease model animals were included in the meta-analysis.Treatment with mesenchymal stem cells significantly improved motor function as assessed by the amphetamine-induced rotational test.Among the stem cell types,the bone marrow MSCs with neurotrophic factor group showed la rgest effect size(SMD[95%CI]=-6.21[-9.50 to-2.93],P=0.0001,I^(2)=0.0%).The stem cell treatment group had significantly more tyrosine hydroxylase positive dopamine rgic neurons in the striatum([95%CI]=1.04[0.59 to 1.49],P=0.0001,I^(2)=65.1%)and substantia nigra(SMD[95%CI]=1.38[0.89 to 1.87],P=0.0001,I^(2)=75.3%),indicating a protective effect on dopaminergic neurons.Subgroup analysis of the amphetamine-induced rotation test showed a significant reduction only in the intracranial-striatum route(SMD[95%CI]=-2.59[-3.25 to-1.94],P=0.0001,I^(2)=74.4%).The memory test showed significant improvement only in the intravenous route(SMD[95%CI]=4.80[1.84 to 7.76],P=0.027,I^(2)=79.6%).Mesenchymal stem cells have been shown to positively impact motor function and memory function and protect dopaminergic neurons in preclinical models of Parkinson’s disease.Further research is required to determine the optimal stem cell types,modifications,transplanted cell numbe rs,and delivery methods for these protocols.
基金funded by the Ramón Areces Foundation.IEC is supported by the Spanish Ministry of Science and Innovation(RYC2019-027287-I)the Spanish Ministry of Economy and Competitiveness(RTI2018-095284-J-100)+1 种基金supported by a grant from ANID/BECAS Chile(Grant No.72180543)through a Margarita Salas grant from the Spanish Ministry Universities。
文摘Background:One of the pathological hallmarks distinguishing Alzheimer’s disease from other dementias is the accumulation of amyloid beta(Aβ).Higher physical activity is associated with decreased dementia risk,and one potential path could be through Aβlevels modulation.We aimed to explore the relationship between physical activity and Aβin middle-aged and older adults.Methods:A systematic search of PubMed,Web of Science,PsycINFO,Cochrane Central Register of Controlled Trials,and SPORTDiscus was performed from inception to April 28,2022.Studies were eligible if they included physical activity and Aβdata in adults aged 45 years or older.Multi-level metaanalyses of intervention and observational studies were performed to examine the role of physical activity in modulating Aβlevels.Results:In total,37 articles were included(8 randomized controlled trials,3 non-randomized controlled trials,4 prospective longitudinal studies,and 22 cross-sectional studies).The overall effect size of physical activity interventions on changes in blood Aβwas medium(pooled standardized mean difference=-0.69,95%confidence interval(95%CI):-1.41 to 0.03;I^(2)=74.6%).However,these results were not statistically significant,and there were not enough studies to explore the effects of physical activity on cerebrospinal fluid(CSF)and brain Aβ.Data from observational studies were examined based on measurements of Aβin the brain using positron emission tomography scans,CSF,and blood.Higher physical activity was positively associated with Aβonly in the CSF(Estimate r=0.12;95%CI:0.05-0.18;I^(2)=38.00%).Conclusion:Physical activity might moderately reduce blood Aβin middle-aged and older adults.However,results were only near statistical significance and might be interpreted with caution given the methodological limitations observed in some of the included studies.In observational studies,higher levels of physical activity were positively associated with Aβonly in CSF.Therefore,further research is needed to understand the modulating role of physical activity in the brain,CSF,and blood Aβ,as well as its implication for cognitive health.
文摘The problems faced the policymakers of the present universities in physical education are how to break away from the traditional models of training,how to set up new systems,how to exploit resources in community and university for physical education,how to make the exercise courses,capacity and time for the inhabitsnts more scientific and reasonable and how to constantly satisfy most exercisers.This paper,by analysing the present situation of university physical education and social physical education,exploits their organic combination,to efficiently train high-qualified and all-round-way-developed talents.
基金provided by the Bazil National Council for Scientific and Technological Development(CNpQ-474184/2013-7)received scholarships from the Brazilian Coordination for the Improvement of Higher Education Personnel(CAPES)
文摘Background: Identifying factors associated with physical activity(PA) is useful in planning interventions and policies. The aim of this study was to identify sociodemographic, biological, and psychosocial factors associated with PA performed in school settings.Methods: Data collected for the present study included gender, age, socioeconomic status, body fat percentage, aerobic fitness, self-efficacy, attitudes,peer and parental support, and perception of school environment. Dependent variables were light-intensity PA(LPA) and moderate-to-vigorousintensity PA(MVPA) performed during school time, recesses, and physical education(PE) classes. Multiple regression analyses were performed.Results: Participating adolescents(n = 567, 53% female, 12.9 ± 5.3 years) spent 5% of school time in MVPA and 27% in LPA, 15% of recesses in MVPA and 44% in LPA, and 16% of PE classes in MVPA and 41% in LPA. Boys engaged in more MVPA in all categories. Age was inversely related with MVPA and LPA in all periods, whereas body fat percentage was inversely related with MVPA in school time and PE classes. Attitude was inversely related with MVPA in all periods and with LPA in recesses. Considering PA to be good and enjoyable was positively associated with MVPA in school time.Conclusion: Adolescents spent little time in PA during school. Future interventions should implement enjoyable activities at school.
文摘Purpose:Given the unique characteristics of physical education(PE) teaching in K-12education,PE teachers' information behaviors deserve special attention.This article reports a survey study of PE teachers' information behaviors,covering information literacy skills and behaviors of information seeking and information use.Design/methodology/approach:A questionnaire survey was conducted of K-12 PE teachers in the Tianjin municipal region of China,with a response rate of 61.9%.Findings:PE teachers lack skills with information retrieval systems in general.The Internet continues to be their primary information source,and they rely more on personal collection and colleagues than the school library for teaching materials.They rarely develop a searching strategy,employ querying tactics,or use advanced search functions,and they tend to be content with finding a few relevant articles.Research limitations:The survey is limited to the Tianjin municipal region in scope.Though attempting to reach 210 participants from 40 schools,it yielded only 130 valid responses.A larger survey covering more regions and with greater responses may be useful.Practical implications:Insights from this study inform the educational and on-job training of K-12 PE teachers to improve their information literacy skills.Originality/value:Little research exists on PE teachers' behaviors of information seeking.This study bridges the gap and enriches our understanding of K-12 teachers' information behaviors.
文摘At present,physical education is listed as the key teaching.This paper introduces the importance of physical education in Colleges and universities,analyzes the current situation of College Physical Education and explores the improvement strategies of College Physical Education at this stage.
基金funded by the General Research Fund(GRF)from Research Grants Council of Hong Kong(to PWCL,project number:GRF 244913)
文摘Objective This study initially validates the Chinese version of the Physical Activity Questionnaire for Older Children(PAQ-C), which has been identified as a potentially valid instrument to assess moderate-to-vigorous physical activity(MVPA) in children among diverse racial groups. Methods The psychometric properties of the PAQ-C with 742 Hong Kong Chinese children were assessed with the scale's internal consistency, reliability, test-retest reliability, confirmatory factory analysis(CFA) in the overall sample, and multistep invariance tests across gender groups as well as convergent validity with body mass index(BMI), and an accelerometry-based MVPA. Results The Cronbach alpha coefficient(α=0.79), composite reliability value(ρ=0.81), and the intraclass correlation coefficient(α=0.82) indicate the satisfactory reliability of the PAQ-C score. The CFA indicated data fit a single factor model, suggesting that the PAQ-C measures only one construct, on MVPA over the previous 7 days. The multiple-group CFAs suggested that the factor loadings and variances and covariances of the PAQ-C measurement model were invariant across gender groups. The PAQ-C score was related to accelerometry-based MVPA(r=0.33) and inversely related to BMI(r=-0.18). Conclusion This study demonstrates the reliability and validity of the PAQ-C in Chinese children.
基金funded by a grant from the National Institute of Child and Human Development(1R15HD071514-01A1)
文摘Background: Although emerging research is demonstrating the potential health impact of exergaming,investigations have primarily been conducted in laboratory settings among small samples with short-term interventions.Information on the effectiveness of exergaming in underserved children's objective physical activity(PA) in population-based settings is also scarce.Moreover,most empirical studies have only included 1 type of exergame in the intervention.Therefore,this study's purpose was to investigate the long-term impact of a multigame exergaming intervention among underserved children integrated within school curricula.Specifically,this study examined the effect of exergaming on children's accelerometer-determined sedentary behavior(SB),light PA,moderate-to-vigorous PA(MVPA),and energy expenditure(EE) over 2 years as compared with regular physical education(PE) classes.Methods: A total of 261 second-and third-grade children(134 girls,127 boys; mean age 8.27 years) were recruited from 2 Texas elementary schools.Children's pre-test 3-day SB,light PA,MVPA,and EE at school were assessed in the fall of 2012.Participants were assigned to 1 of 2groups:(1) exergaming/PE group(125 min weekly of exergaming-based PA program) and (2) comparison group(125 min weekly of PE).PA(SB,light PA,and MVPA) and EE outcome variables were assessed again in 2013(post-test) and 2014(follow-up).Results: Significant time effects were observed for SB(F(1,162)=25.0,p<0.01,η~2= 0.14),light PA(F(1,162)=9.6,p<0.01,η~2= 0.06),and MVPA(F(1,162)=6.2,p=0.01,η~2= 0.04) but not for EE(F(1,162)=0.63,p>0.05,η~2= 0.004).Subsequent pairwise comparisons revealed significant increases from pre-to post-test for light PA(p<0.01),MVPA(p<0.01),and EE(p=0.02) with no changes in SB(p>0.05).Conversely,significant decreases occurred in light PA(p<0.01) from post-test to follow-up with no differences seen in MVPA(p=0.08) and EE(p=0.06) over the same time period.A significant increase was seen,however,for SB from post-test to follow-up.Conclusion: Exergaming PE can have the same positive effect on children's light PA,MVPA,and EE as regular PE.More research is necessary to discern how to promote long-term PA participation after conclusion of the intervention.
基金supported by the Health Research Council of New Zealand Emerging Researcher First Grant (14/565)National Heart Foundation of New Zealand(1602 and 1615)+2 种基金Lottery Health Research Grant (Applic 341129)University of Otago Research Grant (UORG 2014)Dunedin City Council and internal grants from the School of Physical Education,Sport and Exercise Sciences,University of Otago
文摘Objectives:Adolescents using active transport(AT)to school have higher levels of physical activity(PA)compared with motorized transport(MT)users.This study compared school day and weekend day PA in adolescents using AT,MT,or combined AT and MT(AT + MT)to travel to school.Methods:Adolescents(n= 314;age:14.7±1.4 years;32.8% boys)from Dunedin(New Zealand)wore an accelerometer for 7 days and completed a self-reported survey regarding mode of transport to school(73 AT,56 AT + MT,and 185 MT).Data were analyzed using t tests,analysis of variance,and χ2 tests.Results:Although the proportion of adolescents meeting PA guidelines significantly differed among transport groups(AT,47.9%;AT + MT,46.4%;MT,33.5%;p=0.048;overall,39.2%),the observed differences were due mainly to girls.Compared with MT,AT and AT+MT engaged in more moderate-to-vigorous PA(MVPA)per day(AT:61.2 ± 23.2 min;AT+MT:59.6 ± 21.7 min;MT:52.5 ± 19.6 min;p = 0.004;p<0.001,adjusted for gender),per school day and before school.Immediately after school(15:00-16:00),AT engaged in significantly more MVPA compared with AT + MT and MT.No differences in MVPA between the groups were observed in the late afternoon/early evening period during school days or on weekend days.Conclusion:Compared with MT users,adolescent girls using AT or AT + MT accumulated more MVPA during school commute time.AT + MT to school is also a plausible way to increase adolescent girls’ PA when AT only is not feasible.
文摘Background: Physical activity participation(PAP) has been proven to improve health and promote optimal growth among adolescents. However,most adolescents do not meet the current physical activity(PA) recommendations in Turkey. The role of the social environment and social factors on PAP is being increasingly recognized. Although social capital(SC) indicators have been examined in high-income countries, there are few studies on developing countries. The aim of this study was to examine the relationship between SC indicators and PAP among Turkish adolescents.Methods: A survey was conducted among 19 high schools in 4 different cities in Turkey in 2016. A total of 506 female and 729 male high school students participated in this study. The dependent variable was overall PAP, which was measured using the short form of the International Physical Activity Questionnaire. The independent variables included self-perceived family, neighborhood, and school SC. Self-rated health and obesity status, measured by body mass index, were other study covariates in multiple binary logistic regression models. Chi-square tests were used to assess the differences between genders.Results: PAP levels were significantly different between males and females. A higher percentage of males reported PAP(77.4%) compared to females(51.0%). Among males, teacher–student interpersonal trust and informal social control were inversely associated with PAP, while high students interpersonal trust was positively associated with increased odds of PAP. For females, students interpersonal trust was inversely associated with PAP.Conclusion: Various SC indicators are associated with PAP for males and females. These associations are different from findings of studies conducted in developed countries. Therefore, health-promotion interventions and policies should consider gender and different social agents on the social and cultural background to improve PAP among Turkish adolescents.
文摘Background:This study systematically synthesized and quantified the relationship linking state laws governing school physical education(PE)to PE attendance and physical activity(PA)in class and throughout the day and week among students in the USA.Methods:A keyword search was performed in PubMed,Web of Science,Cumulative Index to Nursing and Allied Health Literature(CINAHL),Academic Search Complete,and EconLit.Meta-analyses were performed to estimate the effects of state PE laws.Results:A total of 17 studies were included in the review,and five contributed to the meta-analyses.A total of 8 studies used nationally representative school-or student-level data,three focused on multiple states,and the remaining six examined the PE laws of a single state.The presence and strength of state PE laws were positively associated with PE attendance and the frequency and duration of PA during PE classes and throughout the school day.Compared to those residing in states with weak or no PE laws,students in states with strong PE laws had an additional 0.2 days(95%confidence interval(95%CI):0.10.4)of PE attendance per week and spent an additional 33.9 min(95%CI:22.745.0)participating PE classes per week.State PE laws affected girls’PA more than boys’.Different aspects of state PE laws tended to affect students’PE attendance differently.Disparities in the implementation of state PE laws existed across schools.Conclusion:Future studies should adopt objective measures on PE and PA participation and examine the roles schools and districts play in mediating the effect of state PE laws on students’PE attendance and PA.
基金supported by a National Research Foundation of Korea Grant funded by the Korean Government (NRF2013S1A5A2A03044895 JHP)
文摘Purpose: The purpose of the present study was to determine if there were any differences in various aspects of physical activity such as energy expenditure, intensity, and type of activity between normal-weight and overweight boys.Methods: Children aged 9—12 years were recruited from 2 elementary schools located in different urban districts in Republic of Korea. The present study included 45 Korean boys, of which 19 were normal-weight and 26 were overweight. Daily physical activity was estimated over the same 1-week study period under free-living conditions using the doubly labeled water(DLW) method and a tri-axial accelerometer. Resting metabolic rate(RMR) was measured using the Douglas bag method and open-circuit indirect calorimetry. We calculated the physical activity level(PAL) as the total energy expenditure(TEE)/RMR.Results: PAL was not significantly different between the groups. In the accelerometer data, time spent in locomotive moderate-to-vigorous physical activity(MVPA) was significantly lower in overweight boys than in normal-weight subjects, whereas other variables including non-locomotive activity did not differ between groups. In addition, among all participants, time spent in total locomotive activity was significantly associated with PAL. Time spent in locomotive MVPA was significantly associated with PAL.Conclusion: Overweight boys may be less physically active based on locomotive MVPA, which was positively related with PAL. Our findings suggest that the contribution of locomotive MVPA to the increase in PAL was relatively significant.
