In this paper, the global properties of a mathematical modeling of hepatitis C virus （HCV） with distributed time delays is studied. Lyapunov functionals are constructed to establish the global asymptotic stability o...In this paper, the global properties of a mathematical modeling of hepatitis C virus （HCV） with distributed time delays is studied. Lyapunov functionals are constructed to establish the global asymptotic stability of the uninfected and infected steady states. It is shown that if the basic reproduction number R0 is less than unity, then the uninfected steady state is globally asymptotically stable. If the basic reproduction number R0 is larger than unity, then the infected steady state is globally asymptotically stable.展开更多
In this paper, we investigate global dynamics for a distributed time delayed HCV infec tion model. Our model admits two possible equilibria, an uninfected equilibrium and infected equilibrium depending on the basic re...In this paper, we investigate global dynamics for a distributed time delayed HCV infec tion model. Our model admits two possible equilibria, an uninfected equilibrium and infected equilibrium depending on the basic reproduction number. By employing the method of Lyapunov functional, we prove that the uninfected equilibrium is global asymptotically stable if the basic reproduction number is less than one, it is unsta ble and the infected equilibrium is global asymptotically stable if the basic reproduction number is larger than one. The simulations results are in good accordance with our analytic results.展开更多
文摘In this paper, the global properties of a mathematical modeling of hepatitis C virus （HCV） with distributed time delays is studied. Lyapunov functionals are constructed to establish the global asymptotic stability of the uninfected and infected steady states. It is shown that if the basic reproduction number R0 is less than unity, then the uninfected steady state is globally asymptotically stable. If the basic reproduction number R0 is larger than unity, then the infected steady state is globally asymptotically stable.
文摘In this paper, we investigate global dynamics for a distributed time delayed HCV infec tion model. Our model admits two possible equilibria, an uninfected equilibrium and infected equilibrium depending on the basic reproduction number. By employing the method of Lyapunov functional, we prove that the uninfected equilibrium is global asymptotically stable if the basic reproduction number is less than one, it is unsta ble and the infected equilibrium is global asymptotically stable if the basic reproduction number is larger than one. The simulations results are in good accordance with our analytic results.
