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Radiotherapy combined with transcatheter arterial chemoembolization for unresectable hepatocellular carcinoma–a prospective clinical trial
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作者 Ling Cai Mengzhong Liu +6 位作者 Xiushen Wang Mofa Gu Hui Liu Qun Li Nianji Cui Guohui Li Jinqing Li 《The Chinese-German Journal of Clinical Oncology》 CAS 2008年第2期64-68,共5页
Objective: This study evaluated the therapeutic effect of external beam radiotherapy (RT) combined with trans- catheter arterial chemoembolization (TACE) on the patients with unresectable hepatocellular carcinoma (HCC... Objective: This study evaluated the therapeutic effect of external beam radiotherapy (RT) combined with trans- catheter arterial chemoembolization (TACE) on the patients with unresectable hepatocellular carcinoma (HCC). Methods: From June 1994 to April 2002, 114 patients with unresectable HCC were nonrandomized prospectively stepped into our study. All patients received TACE as initial therapy, except 54 also received combination therapy with external beam therapy. Sur- vival failure patterns were analyzed and compared between the two groups. Results: Overall survival rates in the patients in the radiotherapy group were 65%, 47%, 38% at 1, 2, 3 years, respectively, improved over the non-radiotherapy group rates of 54%, 36.5%, 18% at 1, 2, 3 years, respectively. There was significant difference between two groups (P < 0.05). The survival rates correlated with tumor size, number of tumors, and portal vein embolus. Conclusion: TACE combined with RT is a more effective treatment than TACE alone in patients with unresectable HCC. 展开更多
关键词 RADIOTHERAPY transcatheter arterial chemoembolization hepatocellular carcinoma
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