Security issues in cloud networks and edge computing have become very common. This research focuses on analyzing such issues and developing the best solutions. A detailed literature review has been conducted in this r...Security issues in cloud networks and edge computing have become very common. This research focuses on analyzing such issues and developing the best solutions. A detailed literature review has been conducted in this regard. The findings have shown that many challenges are linked to edge computing, such as privacy concerns, security breaches, high costs, low efficiency, etc. Therefore, there is a need to implement proper security measures to overcome these issues. Using emerging trends, like machine learning, encryption, artificial intelligence, real-time monitoring, etc., can help mitigate security issues. They can also develop a secure and safe future in cloud computing. It was concluded that the security implications of edge computing can easily be covered with the help of new technologies and techniques.展开更多
The traditional Chinese medicine(TCM)industry is critical to not only for public health but also for economic growth.According to the European Union(EU)directives,under the EU framework for(traditional)herbal medicina...The traditional Chinese medicine(TCM)industry is critical to not only for public health but also for economic growth.According to the European Union(EU)directives,under the EU framework for(traditional)herbal medicinal products,herbal medicines with long history of use can be registered in EU.However,there is a condition in this directive in which only those that have at least 10e15 years in the EU market are accepted for registration and/or marketing authorization.In author opinion,the condition of 10-15 years of use in EU countries set within the EU regulatory framework is with consideration of the genetic differences which can result in variation in adverse drug responses among different world populations.With this concept in mind,it is reasonable to project the principal of the EU directive to the Asian countries where TCM is originated.Countries like China,Singapore,Japan and South Korea that have well established drug registration framework are in best position in executing the best practice and facilitate harmonization of registration for TCM within the region.Furthermore,the registration process itself allows more safety and efficacy data to be collected systemically before and after product registration/marketing authorization.These are valuable information for future drug development.The therapeutic value of TCM is limitless,it has been left out in the EU regulatory framework,and the opportunity for it to be expanded and carried forward in modern medicines is shadowed by the limited number of TCM that are qualified to be registered under the EU regulatory framework.An early establishment of a harmonized risk-based registration process for TCM in Asian countries is important.This will strengthen the database to substantiate the history of safe use and further preserving and expanding the therapeutic values of TCM within and beyond the Asian region.展开更多
Monitoring temporal changes in sea level is important in assessing coastal risk.Sea level anomalies at a tide gauge station,if kinematically conceived,include systematic variations such as trend,acceleration,periodic ...Monitoring temporal changes in sea level is important in assessing coastal risk.Sea level anomalies at a tide gauge station,if kinematically conceived,include systematic variations such as trend,acceleration,periodic oscillations,and random disturbances.Among them,the non-stationary nature of the random sea level variations of known or unknown origin at coastal regions has been long recognized by the sea level community.This study proposes the analyses of subgroups of random residual statistics of a rigorously formulated kinematic model solution of tide gauge variations using X-bar and S control charts.The approach is demonstrated using Key West,Florida tide gauge records.The mean and standard errors of 5-year-long subgroups of the residuals revealed that sea level changes at this location have been progressively intensifying from 1913 to the present.Increasing oscillations in sea level at this locality may be attributed partly to the thermal expansion of seawater with increasing temperatures causing larger buoyancy-related sea level fluctuations as well as the intensification of atmospheric events including wind patterns and the impact of changes in inverted barometer effects that will alter coastal risk assessments for the future.展开更多
The“University”proposes the proposition of“investigating things to acquire knowledge”,presenting the rudimentary form of Chinese philosophical epistemology.Over the following 2,500 years,it has undergone numerous ...The“University”proposes the proposition of“investigating things to acquire knowledge”,presenting the rudimentary form of Chinese philosophical epistemology.Over the following 2,500 years,it has undergone numerous debates on the relationship between knowledge and action;however,no philosopher has developed a comprehensive epistemological system that explores the nature,source,formation,application,truth,testing,structure of human knowledge,as well as the relationship between language and thinking.The concept of“know”in the philosophy of“investigating things to attain knowledge”is equivalent to concepts such as“idea”and“meaning”in Western philosophy.However,the cognitive state of“know”has not been fully explored and expanded upon,nor has the distinction between empirical and rational recognition of“know”been made.Confucianism advocated the“learning”of language communication as one of the ways to acquire knowledge,but it failed to evolve a method of using language to conduct formal logical reasoning to acquire knowledge and test truth.The“eight trigrams”deduction and yin-yang and five elements theory in the“I Ching”have stifled the emergence of modern scientific epistemological methods in China in terms of thinking mode.Confucian epistemology:focuses on“reason”and interpersonal relationships,with an emphasis on the establishment of moral ethics and social order.Taoist epistemology:pursues a realm beyond experience and social conventions,understanding the world through introspection and insight;it focuses on grasping“Tao”,providing vague guidance for determining universal truths and acquiring precise knowledge;it is prone to falling into the dilemma of nihilism and relativism.The concept of unity between heaven and man and unity between knowledge and action has led to the lack of differentiation in Chinese philosophical epistemology regarding the study of the relationship between subject and object,not involving the way in which the subject understands the object,the limitations of understanding,and the interaction between subject and object in the process of understanding.展开更多
Cloud computing plays a significant role in modern information technology, providing organizations with numerous benefits, including flexibility, scalability, and cost-efficiency. However, it has become essential for ...Cloud computing plays a significant role in modern information technology, providing organizations with numerous benefits, including flexibility, scalability, and cost-efficiency. However, it has become essential for organizations to ensure the security of their applications, data, and cloud-based networks to use cloud services effectively. This systematic literature review aims to determine the latest information regarding cloud computing security, with a specific emphasis on threats and mitigation strategies. Additionally, it highlights some common threats related to cloud computing security, such as distributed denial-of-service (DDoS) attacks, account hijacking, malware attacks, and data breaches. This research also explores some mitigation strategies, including security awareness training, vulnerability management, security information and event management (SIEM), identity and access management (IAM), and encryption techniques. It discusses emerging trends in cloud security, such as integrating artificial intelligence (AI) and machine learning (ML), serverless computing, and containerization, as well as the effectiveness of the shared responsibility model and its related challenges. The importance of user awareness and the impact of emerging technologies on cloud security have also been discussed in detail to mitigate security risks. A literature review of previous research and scholarly articles has also been conducted to provide insights regarding cloud computing security. It shows the need for continuous research and innovation to address emerging threats and maintain a security-conscious culture in the company.展开更多
The content of current third-wave feminism differs significantly from that of previous feminist movements,which sought equal human and civil rights for women.In third-wave feminism,gender is primarily understood as a ...The content of current third-wave feminism differs significantly from that of previous feminist movements,which sought equal human and civil rights for women.In third-wave feminism,gender is primarily understood as a social category that is linguistically constructed.The now classic work Gender Trouble(1990)by philosopher Judith Butler is decisive for this“linguistic turn”in the social sciences.However,Butler’s work is systematically based on two philosophical traditions that are already highly controversial in themselves:sophism and existentialism,linked to a pre-modern magical worldview.The following essay is a critique of these lines of tradition,followed by the question of the extent to which they can serve citizens of an enlightened society in naming and constructively addressing actual social grievances.展开更多
The three-dimensional(3D)cell culture system has garnered significant attention in recent years as a means of studying cell behavior and tissue development,as opposed to traditional two-dimensional cultures.These syst...The three-dimensional(3D)cell culture system has garnered significant attention in recent years as a means of studying cell behavior and tissue development,as opposed to traditional two-dimensional cultures.These systems can induce specific cell reactions,promote specific tissue functions,and serve as valuable tools for research in tissue engineering,regenerative medicine,and drug discovery.This paper discusses current developments in the field of three-dimensional cell culture and the potential applications of 3D type 1 collagen gels to enhance the growth and maturation of dendritic cells.展开更多
Nanobiomaterials demonstrate great potential in bone and dental tissue regeneration.These materials mimic the natural extracellular matrix in the human body,promoting the controlled release of growth factors and other...Nanobiomaterials demonstrate great potential in bone and dental tissue regeneration.These materials mimic the natural extracellular matrix in the human body,promoting the controlled release of growth factors and other bioactive molecules to enhance tissue regeneration and integration.Nanobioceramics mimic the structure and composition of natural bone.A major challenge in hard tissue healing is creating scaffolds that incorporate stem cells for bone tissue engineering.Scaffolds and implants for regenerative medicine should be designed using computer-aided design(CAD)and three-dimensional(3D)printing to replicate the tissue's anatomical structure.Future studies should examine the relationship between the size of bioceramics and biological reactions.The more interacting nature of nanoceramics better triggers the cellular processes,facilitating the regeneration of calcified tissue.Osteoblasts and osteoclasts are crucial in the development and maintenance of calcified tissue in vivo,and nanoceramics enhance the functionality of orthopedic and dental implants.展开更多
Shifting focus from the patient’s body to the healer’s body,this essay focuses on how Chinese physicians instrumentalized their bodies to heal(ie,body-as-technology)and their hands to think with(ie,hand-memory techn...Shifting focus from the patient’s body to the healer’s body,this essay focuses on how Chinese physicians instrumentalized their bodies to heal(ie,body-as-technology)and their hands to think with(ie,hand-memory techniques or simply,hand mnemonics).When physicians used their hands to memorize concepts related to clinical practice,calculate with time variables,and carry out ritual gestures intended to reduce risk,improve fortune,and even cure,their hands became extensions of their minds.This essay has three parts that follow the discovery process of the author’s research on hand-memory techniques found in Chinese medical texts.The first part“Divination and Revelation”explains the significance of how the author first learned about Chinese divination practices that used hand mnemonics.The second part“Original Frame”introduces the scholarship on arts of memory in Europe that informed interpretations of the earliest hand mnemonics found in Chinese medical texts.The third part“Expanded Frame”deploys some concepts from cognitive science to help situate Chinese medical hand mnemonics more broadly as an example of extended cognition.The essay concludes with an important distinction:sometimes Chinese healers’hands were used separately from their bodies to think through things and sometimes hand and body had to be integrated in order for the healer’s body-as-technology to act as a therapeutically effective instrument.展开更多
This paper focuses on Chinese sources suggested for a narrative medicine(NM)program,called AfterWards.Dr Lauren Small established AfterWards in 2014 and has been coordinating it since out of the Pediatrics Department ...This paper focuses on Chinese sources suggested for a narrative medicine(NM)program,called AfterWards.Dr Lauren Small established AfterWards in 2014 and has been coordinating it since out of the Pediatrics Department at Johns Hopkins Medicine.In early 2019,she started giving a series of lectures and workshops about AfterWards to Chinese medical educators and clinicians in Beijing and Shanghai.She created an AfterWards Facilitator’s Guide based on Western-language sources for workshop participants.She also started to organize with Jiang Yuhong(Peking Union Medical College)a workshop for Chinese colleagues to be held at Johns Hopkins Medicine in October 2019.They invited the author to participate.The idea was hatched then to develop Chinese source materials following the AfterWards structure for an updated Facilitator’s Guide that Dr Small had initially written.A typical one-hour AfterWards session consists of a specific five-part structure:a literary text or artwork,an associated theme,discussion topics,a writing exercise,and shared reflection.While the content of the program always changes from session to session,the basic structure remains the same.This paper summarizes the types of Chinese sources and their related narrative-medicine themes that were originally selected for inclusion in the updated AfterWards Facilitator’s Guide intended for Chinese colleagues.These sources about coping with sick family members,aging,and illness ranged from the textual(classical Chinese poems on aging and diagnostic forms for training students)and visual(premodern Chinese paintings and murals of medical encounters)to the fictive(novels)and performative(contemporary Asian-American film in English and Chinese-language film and documentaries).展开更多
In 2001,internist and literary scholar Rita Charon at Columbia University famously announced a new discipline called narrative medicine.She based it on the premise that the basic humanistic skills of critical reading,...In 2001,internist and literary scholar Rita Charon at Columbia University famously announced a new discipline called narrative medicine.She based it on the premise that the basic humanistic skills of critical reading,slow looking,and reflective writing were as necessary for developing clinical skills as evidence-based medical knowledge.Already by 2011,the new discipline of narrative medicine had taken root in China through published articles and a meeting at the Institute for Medical Humanities(now School of Health Humanities)in Peking University.Just a decade later,narrative medicine programs have not only proliferated in medical schools and hospitals across China but they have also developed into novel programs of“narrative medicine with Chinese characteristics.”展开更多
This paper explores the conversion of raw seawater into drinking water from a religious water literacy (RWL) perspective. RWL is here defined as a socially just water literacy that is based on the respect for the dign...This paper explores the conversion of raw seawater into drinking water from a religious water literacy (RWL) perspective. RWL is here defined as a socially just water literacy that is based on the respect for the dignity of life of all living beings on the Earth. It discusses the importance of sustainable water sources and proposes purification methods. That is, the study aims to show a brief outline of the drinking water source (inland waters;mainly river water) and their purification technologies in recent times and today and propose the purification method (Freezing-Thawing-UV method) in case of taking the seawater as the source. And, it emphasizes the need for dialogue and cooperation between countries in order to proceed. The paper also discusses the relationship among religion, culture, and civilization, and highlights the similarities between Marx’s historical materialism and Umesao’s ecological view. It further discusses the importance of water purification technology, separation methods, and the potential for seawater as an energy source. The paper concludes by discussing the importance of dialogue, communication and understanding environmental decision-making. In order to carry them forward, it is convinced that citizens in the world are nothing but people with self-awareness of “Bodhisattvas of the Earth” as identities. As a result, the new findings that suggest the possibility of raw seawater into drinking water from a religious water literacy perspective through the lens of Kawakatsu’s maritime view have been obtained.展开更多
This scientific paper is a comparative analysis of two mathematical conjectures. The newly proposed -3(-n) - 1 Remer conjecture and how it is related to and a proof of the more well known 3n + 1 Collatz conjecture. An...This scientific paper is a comparative analysis of two mathematical conjectures. The newly proposed -3(-n) - 1 Remer conjecture and how it is related to and a proof of the more well known 3n + 1 Collatz conjecture. An overview of both conjectures and their respective iterative processes will be presented. Showcasing their unique properties and behavior to each other. Through a detailed comparison, we highlight the similarities and differences between these two conjectures and discuss their significance in the field of mathematics. And how they prove each other to be true.展开更多
Herod the Great built palaces and complexes with innovative excellence.This article explores his success in creating unique and luxurious gardens in desert areas.It does this by discussing the interaction between Hero...Herod the Great built palaces and complexes with innovative excellence.This article explores his success in creating unique and luxurious gardens in desert areas.It does this by discussing the interaction between Herodian architecture already excavated by archaeologists and the newer science of garden archaeology.The investigation gives a realistic knowledge,through laboratory analysis of the plants grown in Herod’s gardens and how inventive he was.展开更多
decisions(Quality Decisions)depend on scientific analysis of data.Data are collected,generally,in two ways:1)one sample of suitable size,2)subsequent samples,at regular intervals of time.Often the data are considered ...decisions(Quality Decisions)depend on scientific analysis of data.Data are collected,generally,in two ways:1)one sample of suitable size,2)subsequent samples,at regular intervals of time.Often the data are considered normally distributed.This is wrong because the data must be analysed according to their distribution:Decisions are different.In several cases the data are exponentially distributed:we see how to scientifically deal with Control Charts(CC)to decide;this is opposite to what gives the T Charts that are claimed to be a good method for dealing with“rare events”:The Minitab Software(19&20&21)for“T Charts”is considered.The author will compare some methods,found in the literature with the author’s Theory RIT(Reliability Integral Theory):We will see various cases found in the literature.Classical Shewhart Control Charts and the TBE(Time Between Events)Control Charts have been considered:it appears that with RIT the future decisions will be both sounder and cheaper,for data is exponentially distributed.The novelty of the paper is in the scientific way of dealing with the Control Charts and their Control Limits,both with normally distributed data and with exponentially distributed data.In this way,a lot of wrong published papers on“Time Between Events”are to be discarded,even if their authors claim“We used Standard Statistical methods,typical in the vast literature of similar papers”.The author had to self-cite because it seems the only one that has been fighting for years for“Papers Quality”;he humbly asked the readers to inform him if some people did the same.展开更多
The current research overlaps a linguistic and a legal analysis of public international law in the Ukrainian case.Based on both official documents and public declarations,it explains the grounds for the wide range of ...The current research overlaps a linguistic and a legal analysis of public international law in the Ukrainian case.Based on both official documents and public declarations,it explains the grounds for the wide range of understandings that the two common concepts-peace and war-may be bearing depending of the angle of looking at the matter and depending on the actor invoking them.The study develops the reasons likely to have been considered by President Putin when insisting to refer to the Russian military action started in Ukraine in February 2022 as“special military operation”instead of“war”and the cardinal difference in terms of legal impact for such a linguistic choice.It also builds on the elements which could serve as a basis for achieving a deal in obtaining peace in Ukraine,while tackling on the possible geopolitical,public communication and diplomatic hurdles,and offering clues for strategic analysis of the matter.展开更多
The story of the Garden of Eden is familiar to most people,readers of the Bible or otherwise.I intend in the present article to look afresh at this story and to raise questions about how it is traditionally understood...The story of the Garden of Eden is familiar to most people,readers of the Bible or otherwise.I intend in the present article to look afresh at this story and to raise questions about how it is traditionally understood.To begin,what does the reader of the first book of the Bible,commonly known as“Genesis”,learn about the garden?We are told that trees grow there(Gen 2,9),and rivers have their source there(2,10).Among the trees,three are signalled out for their importance:the tree of life,which stands in the middle of the garden,and which is intimately associated with the tree of the knowing of good and bad.A third tree,which is easily ignored,is a fig tree.When the human couple become aware of their nakedness,we are told that they“sew together fig leaves and make themselves loin clothes”(3,7).(Never mind how they got hold of needle and thread!The nature of the first two of the above-mentioned trees indicates that the reader is introduced into a world of mythology).展开更多
The higher concentration of PM_(10) and PM_(2.5) in the lower atmosphere is severely harmful for human health and it also makes visibility diminution along with weather and climate modifications.The main objective is ...The higher concentration of PM_(10) and PM_(2.5) in the lower atmosphere is severely harmful for human health and it also makes visibility diminution along with weather and climate modifications.The main objective is to find out the spatiotemporal variation and dispersal of PM_(10) and PM_(2.5) along with COVID-19 infection in the dusty city Kolkata.The consecutive two years PM_(10) and PM_(2.5) data of different stations have been obtained from State Pollution Control Board,Govt.of West Bengal.Forward trajectory analysis has been done through HYSPLIT(Hybrid Single Particle Lagrangian Integrated Trajectory)model to find the path and direction of air particles.The result showed that the various meteorological or environmental factors(such as temperature,relative humidity,wind,wind speed,pressure and gusty wind)and geographical location regulate the spatiotemporal variation of PM_(10) and PM_(2.5).These factors like high temperature with relative humidity and strong wind influence to disperse the particulate matters from north to south direction from city to outside during summer in Kolkata metropolitan city.During summer(both pre and lockdown years),the height of particles is extended up to 1000 m owing to active atmospheric ventilation whereas in winter it is confined within 100 m.The HYSPLIT model clearly specified that the particles dispersed from south,south-west to north and north east direction due to strong wind.The constant magnification of PM_(10) and PM_(2.5) in the lower atmosphere leads to greater frequency of COVID-19 infections and deaths.In Kolkata,the one of the crucial reasons of high infection and deaths(COVID-19)is co-morbidity of people.展开更多
Within the public health sector of Hong Kong(China),there is a consensus around the important role of traditional Chinese medicines.For Hong Kong(China)to play a bridging role to bring Chinese medicines to the global ...Within the public health sector of Hong Kong(China),there is a consensus around the important role of traditional Chinese medicines.For Hong Kong(China)to play a bridging role to bring Chinese medicines to the global market requires a concerted effort from the government,academic institutes and industries.The release of the final version of the European Medicines Agencies guidance document,which details the acceptance of minimum requirements to nonclinical package in bibliographical applications,grants the opportunity for well-established and traditional herbal medicines to demonstrate an‘acceptable safe’status for registration in the European Union.It is anticipated that this minimum nonclinical package can be applied to demonstrate the safe use of many traditional Chinese medicines regardless of their eligibility to be registered under the simplified procedure within the European Union.This paper conceptualizes an integration of a simplified evaluation route for eligible proprietary Chinese medicines(pCm)with long history of use into the existing drug regulatory framework in Hong Kong(China).Such integration utilizing the minimum nonclinical package,based on bibliographical data or expert report,as proof of evidence to demonstrate safety for pCm with long history of use requires less demand in scientific resources.With Hong Kong(China)conducting‘first hand’review for eligible pCm,it provides an option for overseas and local pharmaceutical companies to register their products in Hong Kong(China)without the need to rely on issuance of Certificate of Pharmaceutical Product from other countries.This could bring eligible pCm with long history of use to reach international risk-based standard and to be marketed globally as‘medicines’to reach their full therapeutic potential.An important process to positioning Hong Kong(China)to compete with other countries in promoting importation and exportation of pCm to better serve the global health.展开更多
In a previous, primary treatise of the author the mathematical description of electron trajectories in the excited states of the H-atom could be demonstrated, starting from Bohr’s original model but modifying it thre...In a previous, primary treatise of the author the mathematical description of electron trajectories in the excited states of the H-atom could be demonstrated, starting from Bohr’s original model but modifying it three dimensionally. In a subsequent treatise, Bohr’s theorem of an unalterable angular momentum h/2π, determining the ground state of the H-atom, was revealed as an inducement by the—unalterable—electron spin. Starting from this presumption, a model of the H2-molecule could be created which exhibits well-defined electron trajectories, and which enabled computing the bond length precisely. In the present treatise, Bohr’s theorem is adapted to the atom models of helium and of neon. But while this was feasible exactly in the case of helium, the neon atom turned out to be too complex for a mathematical modelling. Nevertheless, a rough ball-and-stick model can be presented, assuming electron rings instead of electron clouds, which in the outer shell are orientated as a tetrahedron. It entails the principal statement that the neon atom does not represent a static construction with constant electron distances and velocities, but a pulsating dynamic one with permanently changing internal distances. Thus, the helium atom marks the limit for precisely describing an atom, whereby at and under this limit such a precise description is feasible, being also demonstrated in the author’s previous work. This contradicts the conventional quantum mechanical theory which claims that such a—locally and temporally—precise description of any atom or molecule structure is generally not possible, also not for the H2-molecule, and not even for the H-atom.展开更多
文摘Security issues in cloud networks and edge computing have become very common. This research focuses on analyzing such issues and developing the best solutions. A detailed literature review has been conducted in this regard. The findings have shown that many challenges are linked to edge computing, such as privacy concerns, security breaches, high costs, low efficiency, etc. Therefore, there is a need to implement proper security measures to overcome these issues. Using emerging trends, like machine learning, encryption, artificial intelligence, real-time monitoring, etc., can help mitigate security issues. They can also develop a secure and safe future in cloud computing. It was concluded that the security implications of edge computing can easily be covered with the help of new technologies and techniques.
文摘The traditional Chinese medicine(TCM)industry is critical to not only for public health but also for economic growth.According to the European Union(EU)directives,under the EU framework for(traditional)herbal medicinal products,herbal medicines with long history of use can be registered in EU.However,there is a condition in this directive in which only those that have at least 10e15 years in the EU market are accepted for registration and/or marketing authorization.In author opinion,the condition of 10-15 years of use in EU countries set within the EU regulatory framework is with consideration of the genetic differences which can result in variation in adverse drug responses among different world populations.With this concept in mind,it is reasonable to project the principal of the EU directive to the Asian countries where TCM is originated.Countries like China,Singapore,Japan and South Korea that have well established drug registration framework are in best position in executing the best practice and facilitate harmonization of registration for TCM within the region.Furthermore,the registration process itself allows more safety and efficacy data to be collected systemically before and after product registration/marketing authorization.These are valuable information for future drug development.The therapeutic value of TCM is limitless,it has been left out in the EU regulatory framework,and the opportunity for it to be expanded and carried forward in modern medicines is shadowed by the limited number of TCM that are qualified to be registered under the EU regulatory framework.An early establishment of a harmonized risk-based registration process for TCM in Asian countries is important.This will strengthen the database to substantiate the history of safe use and further preserving and expanding the therapeutic values of TCM within and beyond the Asian region.
文摘Monitoring temporal changes in sea level is important in assessing coastal risk.Sea level anomalies at a tide gauge station,if kinematically conceived,include systematic variations such as trend,acceleration,periodic oscillations,and random disturbances.Among them,the non-stationary nature of the random sea level variations of known or unknown origin at coastal regions has been long recognized by the sea level community.This study proposes the analyses of subgroups of random residual statistics of a rigorously formulated kinematic model solution of tide gauge variations using X-bar and S control charts.The approach is demonstrated using Key West,Florida tide gauge records.The mean and standard errors of 5-year-long subgroups of the residuals revealed that sea level changes at this location have been progressively intensifying from 1913 to the present.Increasing oscillations in sea level at this locality may be attributed partly to the thermal expansion of seawater with increasing temperatures causing larger buoyancy-related sea level fluctuations as well as the intensification of atmospheric events including wind patterns and the impact of changes in inverted barometer effects that will alter coastal risk assessments for the future.
文摘The“University”proposes the proposition of“investigating things to acquire knowledge”,presenting the rudimentary form of Chinese philosophical epistemology.Over the following 2,500 years,it has undergone numerous debates on the relationship between knowledge and action;however,no philosopher has developed a comprehensive epistemological system that explores the nature,source,formation,application,truth,testing,structure of human knowledge,as well as the relationship between language and thinking.The concept of“know”in the philosophy of“investigating things to attain knowledge”is equivalent to concepts such as“idea”and“meaning”in Western philosophy.However,the cognitive state of“know”has not been fully explored and expanded upon,nor has the distinction between empirical and rational recognition of“know”been made.Confucianism advocated the“learning”of language communication as one of the ways to acquire knowledge,but it failed to evolve a method of using language to conduct formal logical reasoning to acquire knowledge and test truth.The“eight trigrams”deduction and yin-yang and five elements theory in the“I Ching”have stifled the emergence of modern scientific epistemological methods in China in terms of thinking mode.Confucian epistemology:focuses on“reason”and interpersonal relationships,with an emphasis on the establishment of moral ethics and social order.Taoist epistemology:pursues a realm beyond experience and social conventions,understanding the world through introspection and insight;it focuses on grasping“Tao”,providing vague guidance for determining universal truths and acquiring precise knowledge;it is prone to falling into the dilemma of nihilism and relativism.The concept of unity between heaven and man and unity between knowledge and action has led to the lack of differentiation in Chinese philosophical epistemology regarding the study of the relationship between subject and object,not involving the way in which the subject understands the object,the limitations of understanding,and the interaction between subject and object in the process of understanding.
文摘Cloud computing plays a significant role in modern information technology, providing organizations with numerous benefits, including flexibility, scalability, and cost-efficiency. However, it has become essential for organizations to ensure the security of their applications, data, and cloud-based networks to use cloud services effectively. This systematic literature review aims to determine the latest information regarding cloud computing security, with a specific emphasis on threats and mitigation strategies. Additionally, it highlights some common threats related to cloud computing security, such as distributed denial-of-service (DDoS) attacks, account hijacking, malware attacks, and data breaches. This research also explores some mitigation strategies, including security awareness training, vulnerability management, security information and event management (SIEM), identity and access management (IAM), and encryption techniques. It discusses emerging trends in cloud security, such as integrating artificial intelligence (AI) and machine learning (ML), serverless computing, and containerization, as well as the effectiveness of the shared responsibility model and its related challenges. The importance of user awareness and the impact of emerging technologies on cloud security have also been discussed in detail to mitigate security risks. A literature review of previous research and scholarly articles has also been conducted to provide insights regarding cloud computing security. It shows the need for continuous research and innovation to address emerging threats and maintain a security-conscious culture in the company.
文摘The content of current third-wave feminism differs significantly from that of previous feminist movements,which sought equal human and civil rights for women.In third-wave feminism,gender is primarily understood as a social category that is linguistically constructed.The now classic work Gender Trouble(1990)by philosopher Judith Butler is decisive for this“linguistic turn”in the social sciences.However,Butler’s work is systematically based on two philosophical traditions that are already highly controversial in themselves:sophism and existentialism,linked to a pre-modern magical worldview.The following essay is a critique of these lines of tradition,followed by the question of the extent to which they can serve citizens of an enlightened society in naming and constructively addressing actual social grievances.
文摘The three-dimensional(3D)cell culture system has garnered significant attention in recent years as a means of studying cell behavior and tissue development,as opposed to traditional two-dimensional cultures.These systems can induce specific cell reactions,promote specific tissue functions,and serve as valuable tools for research in tissue engineering,regenerative medicine,and drug discovery.This paper discusses current developments in the field of three-dimensional cell culture and the potential applications of 3D type 1 collagen gels to enhance the growth and maturation of dendritic cells.
文摘Nanobiomaterials demonstrate great potential in bone and dental tissue regeneration.These materials mimic the natural extracellular matrix in the human body,promoting the controlled release of growth factors and other bioactive molecules to enhance tissue regeneration and integration.Nanobioceramics mimic the structure and composition of natural bone.A major challenge in hard tissue healing is creating scaffolds that incorporate stem cells for bone tissue engineering.Scaffolds and implants for regenerative medicine should be designed using computer-aided design(CAD)and three-dimensional(3D)printing to replicate the tissue's anatomical structure.Future studies should examine the relationship between the size of bioceramics and biological reactions.The more interacting nature of nanoceramics better triggers the cellular processes,facilitating the regeneration of calcified tissue.Osteoblasts and osteoclasts are crucial in the development and maintenance of calcified tissue in vivo,and nanoceramics enhance the functionality of orthopedic and dental implants.
基金International Consortium for Research in the Humanities(IKJF),University of Erlangen-Nürnberg(2011-2012,2014,2016)Elizabeth and J.Richardson Dilworth Fellow,Institute for Advanced Study,Princeton(2017-2018)+1 种基金National Endowment for Humanities Fellowship,US Government(2019)Visiting Scholar,Max Planck Institute for the History of Science,Berlin(2021-2022).
文摘Shifting focus from the patient’s body to the healer’s body,this essay focuses on how Chinese physicians instrumentalized their bodies to heal(ie,body-as-technology)and their hands to think with(ie,hand-memory techniques or simply,hand mnemonics).When physicians used their hands to memorize concepts related to clinical practice,calculate with time variables,and carry out ritual gestures intended to reduce risk,improve fortune,and even cure,their hands became extensions of their minds.This essay has three parts that follow the discovery process of the author’s research on hand-memory techniques found in Chinese medical texts.The first part“Divination and Revelation”explains the significance of how the author first learned about Chinese divination practices that used hand mnemonics.The second part“Original Frame”introduces the scholarship on arts of memory in Europe that informed interpretations of the earliest hand mnemonics found in Chinese medical texts.The third part“Expanded Frame”deploys some concepts from cognitive science to help situate Chinese medical hand mnemonics more broadly as an example of extended cognition.The essay concludes with an important distinction:sometimes Chinese healers’hands were used separately from their bodies to think through things and sometimes hand and body had to be integrated in order for the healer’s body-as-technology to act as a therapeutically effective instrument.
基金supported by a Visiting Scholar Fellowship at Max Planck Institute for the History of Science, Berlin
文摘This paper focuses on Chinese sources suggested for a narrative medicine(NM)program,called AfterWards.Dr Lauren Small established AfterWards in 2014 and has been coordinating it since out of the Pediatrics Department at Johns Hopkins Medicine.In early 2019,she started giving a series of lectures and workshops about AfterWards to Chinese medical educators and clinicians in Beijing and Shanghai.She created an AfterWards Facilitator’s Guide based on Western-language sources for workshop participants.She also started to organize with Jiang Yuhong(Peking Union Medical College)a workshop for Chinese colleagues to be held at Johns Hopkins Medicine in October 2019.They invited the author to participate.The idea was hatched then to develop Chinese source materials following the AfterWards structure for an updated Facilitator’s Guide that Dr Small had initially written.A typical one-hour AfterWards session consists of a specific five-part structure:a literary text or artwork,an associated theme,discussion topics,a writing exercise,and shared reflection.While the content of the program always changes from session to session,the basic structure remains the same.This paper summarizes the types of Chinese sources and their related narrative-medicine themes that were originally selected for inclusion in the updated AfterWards Facilitator’s Guide intended for Chinese colleagues.These sources about coping with sick family members,aging,and illness ranged from the textual(classical Chinese poems on aging and diagnostic forms for training students)and visual(premodern Chinese paintings and murals of medical encounters)to the fictive(novels)and performative(contemporary Asian-American film in English and Chinese-language film and documentaries).
文摘In 2001,internist and literary scholar Rita Charon at Columbia University famously announced a new discipline called narrative medicine.She based it on the premise that the basic humanistic skills of critical reading,slow looking,and reflective writing were as necessary for developing clinical skills as evidence-based medical knowledge.Already by 2011,the new discipline of narrative medicine had taken root in China through published articles and a meeting at the Institute for Medical Humanities(now School of Health Humanities)in Peking University.Just a decade later,narrative medicine programs have not only proliferated in medical schools and hospitals across China but they have also developed into novel programs of“narrative medicine with Chinese characteristics.”
文摘This paper explores the conversion of raw seawater into drinking water from a religious water literacy (RWL) perspective. RWL is here defined as a socially just water literacy that is based on the respect for the dignity of life of all living beings on the Earth. It discusses the importance of sustainable water sources and proposes purification methods. That is, the study aims to show a brief outline of the drinking water source (inland waters;mainly river water) and their purification technologies in recent times and today and propose the purification method (Freezing-Thawing-UV method) in case of taking the seawater as the source. And, it emphasizes the need for dialogue and cooperation between countries in order to proceed. The paper also discusses the relationship among religion, culture, and civilization, and highlights the similarities between Marx’s historical materialism and Umesao’s ecological view. It further discusses the importance of water purification technology, separation methods, and the potential for seawater as an energy source. The paper concludes by discussing the importance of dialogue, communication and understanding environmental decision-making. In order to carry them forward, it is convinced that citizens in the world are nothing but people with self-awareness of “Bodhisattvas of the Earth” as identities. As a result, the new findings that suggest the possibility of raw seawater into drinking water from a religious water literacy perspective through the lens of Kawakatsu’s maritime view have been obtained.
文摘This scientific paper is a comparative analysis of two mathematical conjectures. The newly proposed -3(-n) - 1 Remer conjecture and how it is related to and a proof of the more well known 3n + 1 Collatz conjecture. An overview of both conjectures and their respective iterative processes will be presented. Showcasing their unique properties and behavior to each other. Through a detailed comparison, we highlight the similarities and differences between these two conjectures and discuss their significance in the field of mathematics. And how they prove each other to be true.
文摘Herod the Great built palaces and complexes with innovative excellence.This article explores his success in creating unique and luxurious gardens in desert areas.It does this by discussing the interaction between Herodian architecture already excavated by archaeologists and the newer science of garden archaeology.The investigation gives a realistic knowledge,through laboratory analysis of the plants grown in Herod’s gardens and how inventive he was.
文摘decisions(Quality Decisions)depend on scientific analysis of data.Data are collected,generally,in two ways:1)one sample of suitable size,2)subsequent samples,at regular intervals of time.Often the data are considered normally distributed.This is wrong because the data must be analysed according to their distribution:Decisions are different.In several cases the data are exponentially distributed:we see how to scientifically deal with Control Charts(CC)to decide;this is opposite to what gives the T Charts that are claimed to be a good method for dealing with“rare events”:The Minitab Software(19&20&21)for“T Charts”is considered.The author will compare some methods,found in the literature with the author’s Theory RIT(Reliability Integral Theory):We will see various cases found in the literature.Classical Shewhart Control Charts and the TBE(Time Between Events)Control Charts have been considered:it appears that with RIT the future decisions will be both sounder and cheaper,for data is exponentially distributed.The novelty of the paper is in the scientific way of dealing with the Control Charts and their Control Limits,both with normally distributed data and with exponentially distributed data.In this way,a lot of wrong published papers on“Time Between Events”are to be discarded,even if their authors claim“We used Standard Statistical methods,typical in the vast literature of similar papers”.The author had to self-cite because it seems the only one that has been fighting for years for“Papers Quality”;he humbly asked the readers to inform him if some people did the same.
文摘The current research overlaps a linguistic and a legal analysis of public international law in the Ukrainian case.Based on both official documents and public declarations,it explains the grounds for the wide range of understandings that the two common concepts-peace and war-may be bearing depending of the angle of looking at the matter and depending on the actor invoking them.The study develops the reasons likely to have been considered by President Putin when insisting to refer to the Russian military action started in Ukraine in February 2022 as“special military operation”instead of“war”and the cardinal difference in terms of legal impact for such a linguistic choice.It also builds on the elements which could serve as a basis for achieving a deal in obtaining peace in Ukraine,while tackling on the possible geopolitical,public communication and diplomatic hurdles,and offering clues for strategic analysis of the matter.
文摘The story of the Garden of Eden is familiar to most people,readers of the Bible or otherwise.I intend in the present article to look afresh at this story and to raise questions about how it is traditionally understood.To begin,what does the reader of the first book of the Bible,commonly known as“Genesis”,learn about the garden?We are told that trees grow there(Gen 2,9),and rivers have their source there(2,10).Among the trees,three are signalled out for their importance:the tree of life,which stands in the middle of the garden,and which is intimately associated with the tree of the knowing of good and bad.A third tree,which is easily ignored,is a fig tree.When the human couple become aware of their nakedness,we are told that they“sew together fig leaves and make themselves loin clothes”(3,7).(Never mind how they got hold of needle and thread!The nature of the first two of the above-mentioned trees indicates that the reader is introduced into a world of mythology).
文摘The higher concentration of PM_(10) and PM_(2.5) in the lower atmosphere is severely harmful for human health and it also makes visibility diminution along with weather and climate modifications.The main objective is to find out the spatiotemporal variation and dispersal of PM_(10) and PM_(2.5) along with COVID-19 infection in the dusty city Kolkata.The consecutive two years PM_(10) and PM_(2.5) data of different stations have been obtained from State Pollution Control Board,Govt.of West Bengal.Forward trajectory analysis has been done through HYSPLIT(Hybrid Single Particle Lagrangian Integrated Trajectory)model to find the path and direction of air particles.The result showed that the various meteorological or environmental factors(such as temperature,relative humidity,wind,wind speed,pressure and gusty wind)and geographical location regulate the spatiotemporal variation of PM_(10) and PM_(2.5).These factors like high temperature with relative humidity and strong wind influence to disperse the particulate matters from north to south direction from city to outside during summer in Kolkata metropolitan city.During summer(both pre and lockdown years),the height of particles is extended up to 1000 m owing to active atmospheric ventilation whereas in winter it is confined within 100 m.The HYSPLIT model clearly specified that the particles dispersed from south,south-west to north and north east direction due to strong wind.The constant magnification of PM_(10) and PM_(2.5) in the lower atmosphere leads to greater frequency of COVID-19 infections and deaths.In Kolkata,the one of the crucial reasons of high infection and deaths(COVID-19)is co-morbidity of people.
文摘Within the public health sector of Hong Kong(China),there is a consensus around the important role of traditional Chinese medicines.For Hong Kong(China)to play a bridging role to bring Chinese medicines to the global market requires a concerted effort from the government,academic institutes and industries.The release of the final version of the European Medicines Agencies guidance document,which details the acceptance of minimum requirements to nonclinical package in bibliographical applications,grants the opportunity for well-established and traditional herbal medicines to demonstrate an‘acceptable safe’status for registration in the European Union.It is anticipated that this minimum nonclinical package can be applied to demonstrate the safe use of many traditional Chinese medicines regardless of their eligibility to be registered under the simplified procedure within the European Union.This paper conceptualizes an integration of a simplified evaluation route for eligible proprietary Chinese medicines(pCm)with long history of use into the existing drug regulatory framework in Hong Kong(China).Such integration utilizing the minimum nonclinical package,based on bibliographical data or expert report,as proof of evidence to demonstrate safety for pCm with long history of use requires less demand in scientific resources.With Hong Kong(China)conducting‘first hand’review for eligible pCm,it provides an option for overseas and local pharmaceutical companies to register their products in Hong Kong(China)without the need to rely on issuance of Certificate of Pharmaceutical Product from other countries.This could bring eligible pCm with long history of use to reach international risk-based standard and to be marketed globally as‘medicines’to reach their full therapeutic potential.An important process to positioning Hong Kong(China)to compete with other countries in promoting importation and exportation of pCm to better serve the global health.
文摘In a previous, primary treatise of the author the mathematical description of electron trajectories in the excited states of the H-atom could be demonstrated, starting from Bohr’s original model but modifying it three dimensionally. In a subsequent treatise, Bohr’s theorem of an unalterable angular momentum h/2π, determining the ground state of the H-atom, was revealed as an inducement by the—unalterable—electron spin. Starting from this presumption, a model of the H2-molecule could be created which exhibits well-defined electron trajectories, and which enabled computing the bond length precisely. In the present treatise, Bohr’s theorem is adapted to the atom models of helium and of neon. But while this was feasible exactly in the case of helium, the neon atom turned out to be too complex for a mathematical modelling. Nevertheless, a rough ball-and-stick model can be presented, assuming electron rings instead of electron clouds, which in the outer shell are orientated as a tetrahedron. It entails the principal statement that the neon atom does not represent a static construction with constant electron distances and velocities, but a pulsating dynamic one with permanently changing internal distances. Thus, the helium atom marks the limit for precisely describing an atom, whereby at and under this limit such a precise description is feasible, being also demonstrated in the author’s previous work. This contradicts the conventional quantum mechanical theory which claims that such a—locally and temporally—precise description of any atom or molecule structure is generally not possible, also not for the H2-molecule, and not even for the H-atom.
