The study focused on the modification with platinum of dark defective titania obtained via pulsed laser ablation. Both the method of Pt introduction and the nature of the Pt precursor were varied. All samples exhibite...The study focused on the modification with platinum of dark defective titania obtained via pulsed laser ablation. Both the method of Pt introduction and the nature of the Pt precursor were varied. All samples exhibited similar phase compositions, specific surface areas, and Pt contents. High-resolution transmission electron microscopy coupled with pulsed CO adsorption revealed increased dispersity when photoreduction and the hydroxonitrate complex (Me _(4) N) _(2) [Pt _(2) (OH) _(2) (NO _(3) ) _(8) ] were used. The sample featured a high content of single-atom species and subnano-sized Pt clusters. The X-ray photoelectron spectroscopy results showed that the photoreduction method facilitated the appearance of a larger number of Pt ^(2+) states, which appeared owing to the strong metal-support interaction (SMSI) eff ect of the transfer of electron density from the electron-saturated defects on the TiO _(2) surface to Pt ^(4+) . In the hydrogen evolution reaction, samples with a significant fraction of the Pt ^(2+) ionic component, capable of generating short-lived Pt^(0) single-atom sites under irradiation due to the SMSI eff ect, exhibited the highest photocatalytic activity. The 0.5Pt(C)/TiO_(2) -Ph sample exhibited the highest hydrogen yield with a quantum efficiency of 0.53, retaining its activity even after 8 h of operation.展开更多
Catalytic properties of the metal-organic framework Cr-MIL-101 in solvent-free cycloaddition of CO2to epoxides to produce cyclic carbonates using tetrabutylammonium bromide as co-catalyst have been explored under mild...Catalytic properties of the metal-organic framework Cr-MIL-101 in solvent-free cycloaddition of CO2to epoxides to produce cyclic carbonates using tetrabutylammonium bromide as co-catalyst have been explored under mild reaction conditions (8 bar CO2, 25C). Styrene and propylene carbonates were formed with high yields (95% and 82%, respectively). Catalytic performance of Cr-MIL-101 was compared with other MOFs: Fe-MIL-101, Zn-MOF-5 and HKUST-1. The catalytic properties of different quaternary ammonium bromides, Cr-MIL-101 as well as PW 12 /Cr-MIL-101 composite material have been assessed in oxidative carboxylation of styrene in the presence of both tert-butyl hydroperoxide and H2O2 as oxidants at 8 100 bar CO2and 25 80C with selectivity to styrene carbonate up to 44% at 57% substrate conversion.展开更多
In the present work we studied the induction periods of hydrate formation of natural gas in pure water, aqueous solutions of surfactants, and in the presence of surfactant together with aluminum oxide nanopowder, the ...In the present work we studied the induction periods of hydrate formation of natural gas in pure water, aqueous solutions of surfactants, and in the presence of surfactant together with aluminum oxide nanopowder, the activity of which as hydrate formation inducer was studied previously. Sodium dodecyl sulfate(SDS) or neonol AF-9-12 were used as the surfactants. It was demonstrated that the addition of either surfactants or aluminum oxide powder under our experimental conditions causes a decrease in the induction period of hydrate formation from ~105 min for pure water to 30–35 min for water with additives. In the case of the simultaneous presence of surfactants and aluminum oxide powder in the system, induction period decreased to ~20 min. So, the synergistic effect of the combination of surfactant and oxide powder on gas hydrate nucleation was demonstrated. Possible reasons of this effect have been discussed.展开更多
For subunit vaccines,adjuvants play a key role in shaping the magnitude,persistence and form of targeted antigen-specific immune response.Flagellin is a potent immune activator by bridging innate inflammatory response...For subunit vaccines,adjuvants play a key role in shaping the magnitude,persistence and form of targeted antigen-specific immune response.Flagellin is a potent immune activator by bridging innate inflammatory responses and adaptive immunity and an adjuvant candidate for clinical application.Calcium phosphate nanoparticles are efficient carriers for different biomolecules like DNA,RNA,peptides and proteins.Flagellin-functionalized calcium phosphate nanoparticles were prepared and their immunostimuiatory effect on the innate immune system,i.e.the cytokine production,was studied.They induced the production of the proinflammatory cytokines IL-8(Caco-2 cells) and IL-1β(bone marrow-derived macrophages;BMDM) in vitro and IL-6 in vivo after intraperitoneal injection in mice.The immunostimulation was more pronounced than with free flagellin.展开更多
As bifunctional oxygen evolution/reduction electrocatalysts,transition-metal-based single-atom-doped nitrogen-carbon(NC)matrices are promising successors of the corresponding noblemetal-based catalysts,offering the ad...As bifunctional oxygen evolution/reduction electrocatalysts,transition-metal-based single-atom-doped nitrogen-carbon(NC)matrices are promising successors of the corresponding noblemetal-based catalysts,offering the advantages of ultrahigh atom utilization effciency and surface active energy.However,the fabrication of such matrices(e.g.,well-dispersed single-atom-doped M-N4/NCs)often requires numerous steps and tedious processes.Herein,ultrasonic plasma engineering allows direct carbonization in a precursor solution containing metal phthalocyanine and aniline.When combining with the dispersion effect of ultrasonic waves,we successfully fabricated uniform single-atom M-N4(M=Fe,Co)carbon catalysts with a production rate as high as 10 mg min-1.The Co-N4/NC presented a bifunctional potential drop ofΔE=0.79 V,outperforming the benchmark Pt/C-Ru/C catalyst(ΔE=0.88 V)at the same catalyst loading.Theoretical calculations revealed that Co-N4 was the major active site with superior O2 adsorption-desorption mechanisms.In a practical Zn-air battery test,the air electrode coated with Co-N4/NC exhibited a specific capacity(762.8 mAh g(-1))and power density(101.62 mW cm^(-2)),exceeding those of Pt/C-Ru/C(700.8 mAh g^(-1) and 89.16 mW cm^(-2),respectively)at the same catalyst loading.Moreover,for Co-N4/NC,the potential difference increased from 1.16 to 1.47 V after 100 charge-discharge cycles.The proposed innovative and scalable strategy was concluded to be well suited for the fabrication of single-atom-doped carbons as promising bifunctional oxygen evolution/reduction electrocatalysts for metal-air batteries.展开更多
The results on a dissociation behavior of propane hydrates prepared from "dry water" and contained unreacted residual water in the form of ice inclusions or supercooled liquid water(water solution of gas) we...The results on a dissociation behavior of propane hydrates prepared from "dry water" and contained unreacted residual water in the form of ice inclusions or supercooled liquid water(water solution of gas) were presented for temperatures below 273 K.The temperature ramping or pressure release method was used for the dissociation of propane hydrate samples.It was found that the mechanism of gas hydrate dissociation at temperatures below 273 K depended on the phase state of unreacted water in the hydrate sample.Gas hydrates dissociated into ice and gas if the ice inclusions were in the hydrate sample.The samples of propane hydrates with inclusions of unreacted supercooled water only(without ice inclusions) dissociated into supercooled water and gas below the pressure of the supercooled water-hydrate-gas metastable equilibrium.展开更多
The surface tension of a promising lead-free solder Au-Bi-Sn alloys was investigated both by the sessile-drop method and calculation. Experimental measurements were carried out for two cross-sections with the constant...The surface tension of a promising lead-free solder Au-Bi-Sn alloys was investigated both by the sessile-drop method and calculation. Experimental measurements were carried out for two cross-sections with the constant gold to bismuth ration of 1:1 and 1:2. For all the investigated compositions, decrease of the surface tension is observed with increasing temperature. Meanwhile, the surface tension values were also calculated based on Butler's equation, with using the newest research on thermodynamics data of Au-Bi-Sn ternary system. Compared with the experimental results, a good agreement was obtained.展开更多
Modern but not entirely coordinated foundations of quantum physics are described in the book “The Quantum Challenge”. The difficulties and philosophical problems of this area of science are discussed. Discussions of...Modern but not entirely coordinated foundations of quantum physics are described in the book “The Quantum Challenge”. The difficulties and philosophical problems of this area of science are discussed. Discussions of many great scientists who paved the foundations of the physics of micro-world are described. These discussions are still urgent. The diversity of interpretations of the wave function, light interference, uncertainty principle, complementarity and completeness of micro-world description are stressed in this book. Difficulties and problems of quantum mechanics described in this book allowed the author of the present communication to propose a new approach based on the infinitely small metrics The difference of infinitesimals in two geometries allows one to explain W. Heisenberg’s uncertainty principle. Interconnection of the images in these geometries is possible with the help of Weierstrass integral transform. This approach allows one to describe the interference of light behind the screen with slits as a sum of the corpuscular component (Weierstrass transform) and the wave component (Fourier transform).展开更多
A novel geometric approach is proposed for the development of the wave-particle notions. This approach is based on a comparison of the two geometries with different sizes of an infinitesimal point. It is assumed that ...A novel geometric approach is proposed for the development of the wave-particle notions. This approach is based on a comparison of the two geometries with different sizes of an infinitesimal point. It is assumed that the smaller is object mass, the larger is the size of the infinitesimal point in comparison with the point of the geometry of macro world. Within this approach, the smaller is object mass, the larger is the uncertainty of its position from the viewpoint of macro objects (macro geometry). This approach provides a natural ex-planation of Heisenberg’s indeterminancy principle. Formally, this approach appears as an unusual operation with an infinitesimal value (point). However, it should be noted that unusual operations (though with infinitely large values) are already known in physics. These are unattainability of the absolute zero of temperature and unattainability of the maximal velocity of movement. Interconnection of the two geometries with different sizes of infinitesimal values is possible with the help of the direct and inverse Weierstrass transformation. At present, diffraction effects are described using the wave notions about the light and Fourier transform. The diffraction of light is usually registered at a distance not less than 1 - 3 metres between the screens in one of which there is a slit or several slits. This distance is about 106 times longer than the wavelength of the radiation. In the present work, an approach is proposed that allows one to describe the light fluxes at short distances between the screens with the help of Fourier and Weierstrass transforms.展开更多
Results? are presented on synthesis?? and crystal growth of? Gd2S3-Dy2S3 solid solution sulfides and study of their thermoelectric properties in the range of temperatures 80-400 K. Gd0.2Dy0.8S1.48 composition has the ...Results? are presented on synthesis?? and crystal growth of? Gd2S3-Dy2S3 solid solution sulfides and study of their thermoelectric properties in the range of temperatures 80-400 K. Gd0.2Dy0.8S1.48 composition has the best values of thermoelectric efficiency 0.39 x 10-3/K at 400 K.展开更多
Porous Si3N4-SiO2-based ceramics with different porosity were prepared via free sintering of Si3N4 on air with an addition of semolina (5, 10 and 20 wt%) as a pore-forming agent. The semolina content in the starting p...Porous Si3N4-SiO2-based ceramics with different porosity were prepared via free sintering of Si3N4 on air with an addition of semolina (5, 10 and 20 wt%) as a pore-forming agent. The semolina content in the starting powder controlled the volume fraction of pores in the sintered body. Small pores (5 μm) formed a continuous network in the whole volume of the ceramic material, while the large pores (~100 μm), formed from the added semolina were mostly isolated in the ceramic matrix. Mercury porosimetry and strength measurements have shown that specific surface area, volume density and compressive strength decreased with the amount of semolina in the samples. Mechanical properties similar to bone were obtained for the sample with 20 wt% semolina pore forming agent (compressive strength 350 MPa, density 2.17 g.cm-3). The prepared Si3N4-SiO2-based ceramics were evaluated for cytotoxic and genotoxic potential on human fibroblast VH10 and B-HNF-1 cells. Biological tests have shown that both these human fibroblast cell lines were sensitive to the samples with lower porosity and cell growth inhibition was observed in the range 14.9% - 21.3%. The cytotoxicity of the sample with the highest porosity (~40%) was not significant (10%). The microscopic observations have shown that VH10 and B-HNF-1 cells growing around the silicon nitride ceramic discs were homogeneously distributed on the cultivation surface. No significant morphologic changes were found in treated cells, their morphology was very similar to that of the control cells. None of the tested Si3N4-based ceramic samples induced necrotic/apoptotic death of human fibroblasts. Sample S-20 had similar properties to bones and was characterized by very good biocompatibility, slight cytotoxicity and none genotoxicity. Therefore, Si3N4-SiO2-based ceramics prepared by free sintering on air are potential biomaterials for medical applications.展开更多
Achievable supercooling for the formation of methane hydrate from water emulsions was studied in seven different crude oils and in decane. The experiments were performed under constant rate cooling from + 20 to-15 ...Achievable supercooling for the formation of methane hydrate from water emulsions was studied in seven different crude oils and in decane. The experiments were performed under constant rate cooling from + 20 to-15 °C and a pressure of methane of 12 MPa. It was demonstrated that the shapes and positions of the resulting survival curves depend on the density, viscosity and dispersive power of oil samples used in the experiments, as well as on the degree of oil oxidation. In addition, results of the experiments on ice freezing under the same emulsions are presented. The results obtained in the work allowed us to discuss the possibility and features of primary and secondary nucleation of the hydrate and ice in the systems under consideration.展开更多
In this article the plasma-chemical synthesis of nanosized powders(nitrides,carbides,oxides,carbon nanotubes and fullerenes) is reviewed.Nanosized powders-nitrides,carbides,oxides,carbon nanotubes and fullerenes have ...In this article the plasma-chemical synthesis of nanosized powders(nitrides,carbides,oxides,carbon nanotubes and fullerenes) is reviewed.Nanosized powders-nitrides,carbides,oxides,carbon nanotubes and fullerenes have been successfully produced using different techniques,technological apparatuses and conditions for their plasma-chemical synthesis.展开更多
Mineral data from Yakutian kimberlites allow reconstruction of the history of lithospheric mantle.Differences occur in compositions of mantle pyropes and clinopyroxenes from large kimberlite pipes in the Alakit and Da...Mineral data from Yakutian kimberlites allow reconstruction of the history of lithospheric mantle.Differences occur in compositions of mantle pyropes and clinopyroxenes from large kimberlite pipes in the Alakit and Daldyn fields.In the Alakit field.Cr-diopsides are alkaline,and Stykanskaya and some other pipes contain more sub-calcic pyropes and dunitic-type diamond inclusions,while in the Daldyn field harzburgitic pyropes are frequent.The eclogitic diamond inclusions in the Alakit field are sharply divided in types and conditions,while in the Daldyn field they show varying compositions and often continuous Pressure-Temperature(P-T) ranges with increasing Fe~# with decreasing pressures.In Alakit,Crpargasites to richterites were found in all pipes,while in Daldyn,pargasites are rare Dalnyaya and Zarnitsa pipes.Cr-diopsides from the Alakit region show higher levels of light Rare Earth Elements(LREE)and stronger REE-slopes,and enrichment in light Rare Earth Elements(LREE),sometimes Th-U,and small troughs in Nb-Ta-Zr.In the Daldyn field,the High Field Strength Elements HFSE troughs are more common in clinopyroxenes with low REE abundances,while those from sheared and refertilized peridotites have smooth patterns.Garnets from Alakit show HREE minima,but those from Daldyn often have a trough at Yand high U and Pb.PTX/O2 diagrams from both regions show similarities,suggesting similar layering and structures.The degree of metasomatism is often higher for pipes which show dispersion in P-Fe~# trends for garnets.In the mantle beneath Udachnaya and Aykhal,pipes show 6-7 linear arrays of P-Fe~# in the lower part of the mantle section at 7.5-3.0 GPa,probably reflecting primary subduction horizons.Beneath the Sytykanskaya pipe,there are several horizons with opposite inclinations which reflect metasomatic processes.The high dispersion of the P—Fe~# trend indicating widespread metasomatism is associated with decreased diamond grades.Possible explanation of the differences in mineralogy and geochemistry of the mantle sections may relate to their tectonic positions during growth of the lithospheric keel.Enrichment in volatiles and alkalis possibly corresponds to interaction with subduction-related fluids and melts in the craton margins.Incorporation of island arc peridotites from an eroded arc is a possible scenario.展开更多
Methane and carbon dioxide hydrates are one of the possible forms in which these gases exist in natural coal(for more detailed discussion see Refs [1,2]). In this work, the decomposition of carbon dioxide hydrate in f...Methane and carbon dioxide hydrates are one of the possible forms in which these gases exist in natural coal(for more detailed discussion see Refs [1,2]). In this work, the decomposition of carbon dioxide hydrate in five samples of natural coal differing from each other in metamorphism degree was investigated experimentally. Carbon dioxide hydrate dispersed in coals was synthesized from water adsorbed in these coals. During a linear temperature rise in an autoclave with the coal + hydrate sample the hydrate decomposition manifests itself as a step of increase in gas pressure, accompanied by a decrease/stabilization of the temperature of coal sample. The dependencies of the amount of hydrate formed on initial coal humidity and on gas pressure during hydrate formation were studied. It was demonstrated that each coal sample is characterized by its own humidity threshold below which hydrate formation in natural coal is impossible. With an increase in gas pressure, the amount of water transformed into hydrate increases. For the studied coal samples, the decomposition of carbon dioxide hydrates proceeds within a definite temperature and pressure range, and this range is close to the curve of phase equilibrium for bulk hydrate.展开更多
A new laser-plasma deposition method has been developed for the plasma chemical deposition of hard silicon carbonitride coatings on stainless steel substrates from the hexamethyldisilazane (HMDS) Si<sub><span...A new laser-plasma deposition method has been developed for the plasma chemical deposition of hard silicon carbonitride coatings on stainless steel substrates from the hexamethyldisilazane (HMDS) Si<sub><span style="font-size:12px;font-family:Verdana;">2</span></sub><span style="font-family:Verdana;">NH(CH</span><sub><span style="font-size:12px;font-family:Verdana;">3</span></sub><span style="font-family:Verdana;">)</span><sub><span style="font-size:12px;font-family:Verdana;">6</span></sub><span style="font-family:Verdana;"> vapor in a high-speed Ar and Ar</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">+</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">10 vol.% He gas stream at the HMDS gas flow activation after the laser beam focus. The method allows depositing silicon carbonitride coatings at the rate of 0.4</span><span style="font-family:Verdana;"> - </span><span style="font-family:;" "=""><span style="font-family:Verdana;">1.2 μm·min</span><sup><span style="font-size:12px;font-family:Verdana;">-1</span></sup><span style="font-family:Verdana;">, </span><i><span style="font-family:Verdana;">i.e.</span></i><span style="font-family:Verdana;"> ~2 times higher than that at introducing HMDS in the laser beam focus zone. The properties of the prepared coatings have been studied by the methods of IR and Raman spectroscopy, atomic force microscopy, nanoindentation and X-ray diffraction (XRD) analysis. Studying the film structure with the use of XRD showed that the prepared silicon carbonitride coatings are X-ray amorphous. It has been found that the coating deposition rate and the structure of coatings depend on the process parameters: HMDS flow rate and plasma-generating gas (argon or (Ar +</span></span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">He). The method allows depositing SiCN films at a high speed and a hardness of 20</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">22 GPa.</span>展开更多
Gas hydrates and wax are the major flow assurance problems for the transportation of produced hydrocarbons through pipelines.However,in most research works both these two problems are studied separately.Although simul...Gas hydrates and wax are the major flow assurance problems for the transportation of produced hydrocarbons through pipelines.However,in most research works both these two problems are studied separately.Although simultaneous precipitation or deposition of these compounds in pipelines can lead to different mitigation/prevention strategies,the investi-gations in which both these problems are considered simultaneously appeared only recently.There is no information in the literature on the texture/composition and features of decomposition process of mixed wax/hydrate plugs.At the same time,this information could be useful to understand how to treat the problem of formation of these plugs.In this work,three wax/gas hydrate plugs were collected at quasi-static conditions from a water-in-oil emulsion to study their texture,composition and the features of decomposition process.Powder X-ray diffraction and IR(infrared spectroscopy)analyses showed that the plugs consisted of wax and gas hydrate.Thermovolumetric and DSC(Differential Scanning Calorimetry)experiments showed that the main part of gas hydrate in the plugs at the ambient pressure started to decompose at about 268 K.This temperature was higher than the equilibrium temperature of carbon dioxide hydrate at this pressure,indicating that the gas hydrate in the plugs could be effectively preserved at temperatures below the ice melting point(273.2 K).It was found through observation of the hydrate decomposition process in the plugs under the microscope that the gas in the samples released in small bubbles,while the hydrate particles were not visible at this magnification,indicating that the hydrate was indeed highly dispersed in the samples.A residual wax was jelly-like after decomposition of hydrate in all the cases.Rheological experiments showed that the plugs residues after decomposition of the hydrates had higher yield points and viscosities than the initial waxy crude oil origi-nally used for the experiments.展开更多
In this work, an analysis of the regularities of the electrolytic dissociation of aryl derivatives of the succinic acid (phenylsuccinic, benzylsuccinic, dibenzylsuccinic and phenyl-2-benzylsuccinic acids) in their dil...In this work, an analysis of the regularities of the electrolytic dissociation of aryl derivatives of the succinic acid (phenylsuccinic, benzylsuccinic, dibenzylsuccinic and phenyl-2-benzylsuccinic acids) in their dilute (0.0001 - 0.01 mol.dm-3) solutions was carried out with the aid of a new method of determination of the dissociation parameters of weak multibasic organic acids with the “overlapping equilibria” effect previously described by authors. Values of the usual and “partial” degrees of dissociation, the concentrations of all anions, hydrogen ions and undissociated acid molecules, the activity coefficients of all charged dissociation products were calculated. Together with the accurate equations, the simple empirical equations for fast approximate determination of the various dissociation parameters were also suggested.展开更多
文摘The study focused on the modification with platinum of dark defective titania obtained via pulsed laser ablation. Both the method of Pt introduction and the nature of the Pt precursor were varied. All samples exhibited similar phase compositions, specific surface areas, and Pt contents. High-resolution transmission electron microscopy coupled with pulsed CO adsorption revealed increased dispersity when photoreduction and the hydroxonitrate complex (Me _(4) N) _(2) [Pt _(2) (OH) _(2) (NO _(3) ) _(8) ] were used. The sample featured a high content of single-atom species and subnano-sized Pt clusters. The X-ray photoelectron spectroscopy results showed that the photoreduction method facilitated the appearance of a larger number of Pt ^(2+) states, which appeared owing to the strong metal-support interaction (SMSI) eff ect of the transfer of electron density from the electron-saturated defects on the TiO _(2) surface to Pt ^(4+) . In the hydrogen evolution reaction, samples with a significant fraction of the Pt ^(2+) ionic component, capable of generating short-lived Pt^(0) single-atom sites under irradiation due to the SMSI eff ect, exhibited the highest photocatalytic activity. The 0.5Pt(C)/TiO_(2) -Ph sample exhibited the highest hydrogen yield with a quantum efficiency of 0.53, retaining its activity even after 8 h of operation.
基金the Russian Foundation for Basic Research(RFBR grant12-03-31537)
文摘Catalytic properties of the metal-organic framework Cr-MIL-101 in solvent-free cycloaddition of CO2to epoxides to produce cyclic carbonates using tetrabutylammonium bromide as co-catalyst have been explored under mild reaction conditions (8 bar CO2, 25C). Styrene and propylene carbonates were formed with high yields (95% and 82%, respectively). Catalytic performance of Cr-MIL-101 was compared with other MOFs: Fe-MIL-101, Zn-MOF-5 and HKUST-1. The catalytic properties of different quaternary ammonium bromides, Cr-MIL-101 as well as PW 12 /Cr-MIL-101 composite material have been assessed in oxidative carboxylation of styrene in the presence of both tert-butyl hydroperoxide and H2O2 as oxidants at 8 100 bar CO2and 25 80C with selectivity to styrene carbonate up to 44% at 57% substrate conversion.
文摘In the present work we studied the induction periods of hydrate formation of natural gas in pure water, aqueous solutions of surfactants, and in the presence of surfactant together with aluminum oxide nanopowder, the activity of which as hydrate formation inducer was studied previously. Sodium dodecyl sulfate(SDS) or neonol AF-9-12 were used as the surfactants. It was demonstrated that the addition of either surfactants or aluminum oxide powder under our experimental conditions causes a decrease in the induction period of hydrate formation from ~105 min for pure water to 30–35 min for water with additives. In the case of the simultaneous presence of surfactants and aluminum oxide powder in the system, induction period decreased to ~20 min. So, the synergistic effect of the combination of surfactant and oxide powder on gas hydrate nucleation was demonstrated. Possible reasons of this effect have been discussed.
基金supported by the Deutsche Forschungsgemeinschaft(SFB/Transregio 60)the National Natural Science Foundation of China(no.81302609 and 81202312)
文摘For subunit vaccines,adjuvants play a key role in shaping the magnitude,persistence and form of targeted antigen-specific immune response.Flagellin is a potent immune activator by bridging innate inflammatory responses and adaptive immunity and an adjuvant candidate for clinical application.Calcium phosphate nanoparticles are efficient carriers for different biomolecules like DNA,RNA,peptides and proteins.Flagellin-functionalized calcium phosphate nanoparticles were prepared and their immunostimuiatory effect on the innate immune system,i.e.the cytokine production,was studied.They induced the production of the proinflammatory cytokines IL-8(Caco-2 cells) and IL-1β(bone marrow-derived macrophages;BMDM) in vitro and IL-6 in vivo after intraperitoneal injection in mice.The immunostimulation was more pronounced than with free flagellin.
基金supported by Global Frontier Program through the Global Frontier Hybrid Interface materials(GFHIM)of the National Research Foundation of Korea(NRF)funded by the ministry of science,ICT and Future Planning(2013M3A6B1078874)co-supported by Busan Innovation Institute of Industry,Science&Technology Planning(BISTEP)+1 种基金the financial support of Federal Ministry of Education and Research(BMBF)under the“Make Our Planet Great Again-German Research Initiative”(MOPGAGRI),57429784implemented by the German Academic Exchange Service Deutscher Akademischer Austauschdienst(DAAD)。
文摘As bifunctional oxygen evolution/reduction electrocatalysts,transition-metal-based single-atom-doped nitrogen-carbon(NC)matrices are promising successors of the corresponding noblemetal-based catalysts,offering the advantages of ultrahigh atom utilization effciency and surface active energy.However,the fabrication of such matrices(e.g.,well-dispersed single-atom-doped M-N4/NCs)often requires numerous steps and tedious processes.Herein,ultrasonic plasma engineering allows direct carbonization in a precursor solution containing metal phthalocyanine and aniline.When combining with the dispersion effect of ultrasonic waves,we successfully fabricated uniform single-atom M-N4(M=Fe,Co)carbon catalysts with a production rate as high as 10 mg min-1.The Co-N4/NC presented a bifunctional potential drop ofΔE=0.79 V,outperforming the benchmark Pt/C-Ru/C catalyst(ΔE=0.88 V)at the same catalyst loading.Theoretical calculations revealed that Co-N4 was the major active site with superior O2 adsorption-desorption mechanisms.In a practical Zn-air battery test,the air electrode coated with Co-N4/NC exhibited a specific capacity(762.8 mAh g(-1))and power density(101.62 mW cm^(-2)),exceeding those of Pt/C-Ru/C(700.8 mAh g^(-1) and 89.16 mW cm^(-2),respectively)at the same catalyst loading.Moreover,for Co-N4/NC,the potential difference increased from 1.16 to 1.47 V after 100 charge-discharge cycles.The proposed innovative and scalable strategy was concluded to be well suited for the fabrication of single-atom-doped carbons as promising bifunctional oxygen evolution/reduction electrocatalysts for metal-air batteries.
基金supported by the Council for Grants of the President of the Russian Federation(Grant NSh–3929.2014.5)the Basic Research Programs of the RAS(Program No.8,and Program the Arctic)the Siberian Branch of the RAS(Interdisciplinary Project No.144)
文摘The results on a dissociation behavior of propane hydrates prepared from "dry water" and contained unreacted residual water in the form of ice inclusions or supercooled liquid water(water solution of gas) were presented for temperatures below 273 K.The temperature ramping or pressure release method was used for the dissociation of propane hydrate samples.It was found that the mechanism of gas hydrate dissociation at temperatures below 273 K depended on the phase state of unreacted water in the hydrate sample.Gas hydrates dissociated into ice and gas if the ice inclusions were in the hydrate sample.The samples of propane hydrates with inclusions of unreacted supercooled water only(without ice inclusions) dissociated into supercooled water and gas below the pressure of the supercooled water-hydrate-gas metastable equilibrium.
基金supported by the National Natural Science Foundation of China (No. 50972010)the Fundamental Research Funds for the Central Universities (No. FRF-TP-09-021B)the Austrian Science Foundation (No. P20488-N19)
文摘The surface tension of a promising lead-free solder Au-Bi-Sn alloys was investigated both by the sessile-drop method and calculation. Experimental measurements were carried out for two cross-sections with the constant gold to bismuth ration of 1:1 and 1:2. For all the investigated compositions, decrease of the surface tension is observed with increasing temperature. Meanwhile, the surface tension values were also calculated based on Butler's equation, with using the newest research on thermodynamics data of Au-Bi-Sn ternary system. Compared with the experimental results, a good agreement was obtained.
文摘Modern but not entirely coordinated foundations of quantum physics are described in the book “The Quantum Challenge”. The difficulties and philosophical problems of this area of science are discussed. Discussions of many great scientists who paved the foundations of the physics of micro-world are described. These discussions are still urgent. The diversity of interpretations of the wave function, light interference, uncertainty principle, complementarity and completeness of micro-world description are stressed in this book. Difficulties and problems of quantum mechanics described in this book allowed the author of the present communication to propose a new approach based on the infinitely small metrics The difference of infinitesimals in two geometries allows one to explain W. Heisenberg’s uncertainty principle. Interconnection of the images in these geometries is possible with the help of Weierstrass integral transform. This approach allows one to describe the interference of light behind the screen with slits as a sum of the corpuscular component (Weierstrass transform) and the wave component (Fourier transform).
文摘A novel geometric approach is proposed for the development of the wave-particle notions. This approach is based on a comparison of the two geometries with different sizes of an infinitesimal point. It is assumed that the smaller is object mass, the larger is the size of the infinitesimal point in comparison with the point of the geometry of macro world. Within this approach, the smaller is object mass, the larger is the uncertainty of its position from the viewpoint of macro objects (macro geometry). This approach provides a natural ex-planation of Heisenberg’s indeterminancy principle. Formally, this approach appears as an unusual operation with an infinitesimal value (point). However, it should be noted that unusual operations (though with infinitely large values) are already known in physics. These are unattainability of the absolute zero of temperature and unattainability of the maximal velocity of movement. Interconnection of the two geometries with different sizes of infinitesimal values is possible with the help of the direct and inverse Weierstrass transformation. At present, diffraction effects are described using the wave notions about the light and Fourier transform. The diffraction of light is usually registered at a distance not less than 1 - 3 metres between the screens in one of which there is a slit or several slits. This distance is about 106 times longer than the wavelength of the radiation. In the present work, an approach is proposed that allows one to describe the light fluxes at short distances between the screens with the help of Fourier and Weierstrass transforms.
文摘Results? are presented on synthesis?? and crystal growth of? Gd2S3-Dy2S3 solid solution sulfides and study of their thermoelectric properties in the range of temperatures 80-400 K. Gd0.2Dy0.8S1.48 composition has the best values of thermoelectric efficiency 0.39 x 10-3/K at 400 K.
基金This study was supported by the Technology Assistance Agency under the contract no.APVV-0500-10the Slovak State Committee for Scientific Research VEGA,grant 1/0165/10.
文摘Porous Si3N4-SiO2-based ceramics with different porosity were prepared via free sintering of Si3N4 on air with an addition of semolina (5, 10 and 20 wt%) as a pore-forming agent. The semolina content in the starting powder controlled the volume fraction of pores in the sintered body. Small pores (5 μm) formed a continuous network in the whole volume of the ceramic material, while the large pores (~100 μm), formed from the added semolina were mostly isolated in the ceramic matrix. Mercury porosimetry and strength measurements have shown that specific surface area, volume density and compressive strength decreased with the amount of semolina in the samples. Mechanical properties similar to bone were obtained for the sample with 20 wt% semolina pore forming agent (compressive strength 350 MPa, density 2.17 g.cm-3). The prepared Si3N4-SiO2-based ceramics were evaluated for cytotoxic and genotoxic potential on human fibroblast VH10 and B-HNF-1 cells. Biological tests have shown that both these human fibroblast cell lines were sensitive to the samples with lower porosity and cell growth inhibition was observed in the range 14.9% - 21.3%. The cytotoxicity of the sample with the highest porosity (~40%) was not significant (10%). The microscopic observations have shown that VH10 and B-HNF-1 cells growing around the silicon nitride ceramic discs were homogeneously distributed on the cultivation surface. No significant morphologic changes were found in treated cells, their morphology was very similar to that of the control cells. None of the tested Si3N4-based ceramic samples induced necrotic/apoptotic death of human fibroblasts. Sample S-20 had similar properties to bones and was characterized by very good biocompatibility, slight cytotoxicity and none genotoxicity. Therefore, Si3N4-SiO2-based ceramics prepared by free sintering on air are potential biomaterials for medical applications.
基金the Federal Agency for Scientific Organizations for funding
文摘Achievable supercooling for the formation of methane hydrate from water emulsions was studied in seven different crude oils and in decane. The experiments were performed under constant rate cooling from + 20 to-15 °C and a pressure of methane of 12 MPa. It was demonstrated that the shapes and positions of the resulting survival curves depend on the density, viscosity and dispersive power of oil samples used in the experiments, as well as on the degree of oil oxidation. In addition, results of the experiments on ice freezing under the same emulsions are presented. The results obtained in the work allowed us to discuss the possibility and features of primary and secondary nucleation of the hydrate and ice in the systems under consideration.
基金supported by the National Science Fund of the Bulgarian Ministry of Education and Science (Project DO 02-199/17.12.2008)
文摘In this article the plasma-chemical synthesis of nanosized powders(nitrides,carbides,oxides,carbon nanotubes and fullerenes) is reviewed.Nanosized powders-nitrides,carbides,oxides,carbon nanotubes and fullerenes have been successfully produced using different techniques,technological apparatuses and conditions for their plasma-chemical synthesis.
基金Supported by Grants RBRF 05-05-64718,03-05-6414611-0500060a+2 种基金11-05-91060-PICSa16-05-860the result of the projects 77-2,65-03,02-05 UIGGM SD RAS and ALROSA Stock Company
文摘Mineral data from Yakutian kimberlites allow reconstruction of the history of lithospheric mantle.Differences occur in compositions of mantle pyropes and clinopyroxenes from large kimberlite pipes in the Alakit and Daldyn fields.In the Alakit field.Cr-diopsides are alkaline,and Stykanskaya and some other pipes contain more sub-calcic pyropes and dunitic-type diamond inclusions,while in the Daldyn field harzburgitic pyropes are frequent.The eclogitic diamond inclusions in the Alakit field are sharply divided in types and conditions,while in the Daldyn field they show varying compositions and often continuous Pressure-Temperature(P-T) ranges with increasing Fe~# with decreasing pressures.In Alakit,Crpargasites to richterites were found in all pipes,while in Daldyn,pargasites are rare Dalnyaya and Zarnitsa pipes.Cr-diopsides from the Alakit region show higher levels of light Rare Earth Elements(LREE)and stronger REE-slopes,and enrichment in light Rare Earth Elements(LREE),sometimes Th-U,and small troughs in Nb-Ta-Zr.In the Daldyn field,the High Field Strength Elements HFSE troughs are more common in clinopyroxenes with low REE abundances,while those from sheared and refertilized peridotites have smooth patterns.Garnets from Alakit show HREE minima,but those from Daldyn often have a trough at Yand high U and Pb.PTX/O2 diagrams from both regions show similarities,suggesting similar layering and structures.The degree of metasomatism is often higher for pipes which show dispersion in P-Fe~# trends for garnets.In the mantle beneath Udachnaya and Aykhal,pipes show 6-7 linear arrays of P-Fe~# in the lower part of the mantle section at 7.5-3.0 GPa,probably reflecting primary subduction horizons.Beneath the Sytykanskaya pipe,there are several horizons with opposite inclinations which reflect metasomatic processes.The high dispersion of the P—Fe~# trend indicating widespread metasomatism is associated with decreased diamond grades.Possible explanation of the differences in mineralogy and geochemistry of the mantle sections may relate to their tectonic positions during growth of the lithospheric keel.Enrichment in volatiles and alkalis possibly corresponds to interaction with subduction-related fluids and melts in the craton margins.Incorporation of island arc peridotites from an eroded arc is a possible scenario.
基金supported by the project №18 "Study of the physicochemical properties of hydrate-containing rocks for the development of remote sensing methods and the characteristics of natural accumulations of gas hydrates" of the Integrated Basic Research Program of the Siberian Branch of the Russian Academy of Sciences.
文摘Methane and carbon dioxide hydrates are one of the possible forms in which these gases exist in natural coal(for more detailed discussion see Refs [1,2]). In this work, the decomposition of carbon dioxide hydrate in five samples of natural coal differing from each other in metamorphism degree was investigated experimentally. Carbon dioxide hydrate dispersed in coals was synthesized from water adsorbed in these coals. During a linear temperature rise in an autoclave with the coal + hydrate sample the hydrate decomposition manifests itself as a step of increase in gas pressure, accompanied by a decrease/stabilization of the temperature of coal sample. The dependencies of the amount of hydrate formed on initial coal humidity and on gas pressure during hydrate formation were studied. It was demonstrated that each coal sample is characterized by its own humidity threshold below which hydrate formation in natural coal is impossible. With an increase in gas pressure, the amount of water transformed into hydrate increases. For the studied coal samples, the decomposition of carbon dioxide hydrates proceeds within a definite temperature and pressure range, and this range is close to the curve of phase equilibrium for bulk hydrate.
文摘A new laser-plasma deposition method has been developed for the plasma chemical deposition of hard silicon carbonitride coatings on stainless steel substrates from the hexamethyldisilazane (HMDS) Si<sub><span style="font-size:12px;font-family:Verdana;">2</span></sub><span style="font-family:Verdana;">NH(CH</span><sub><span style="font-size:12px;font-family:Verdana;">3</span></sub><span style="font-family:Verdana;">)</span><sub><span style="font-size:12px;font-family:Verdana;">6</span></sub><span style="font-family:Verdana;"> vapor in a high-speed Ar and Ar</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">+</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">10 vol.% He gas stream at the HMDS gas flow activation after the laser beam focus. The method allows depositing silicon carbonitride coatings at the rate of 0.4</span><span style="font-family:Verdana;"> - </span><span style="font-family:;" "=""><span style="font-family:Verdana;">1.2 μm·min</span><sup><span style="font-size:12px;font-family:Verdana;">-1</span></sup><span style="font-family:Verdana;">, </span><i><span style="font-family:Verdana;">i.e.</span></i><span style="font-family:Verdana;"> ~2 times higher than that at introducing HMDS in the laser beam focus zone. The properties of the prepared coatings have been studied by the methods of IR and Raman spectroscopy, atomic force microscopy, nanoindentation and X-ray diffraction (XRD) analysis. Studying the film structure with the use of XRD showed that the prepared silicon carbonitride coatings are X-ray amorphous. It has been found that the coating deposition rate and the structure of coatings depend on the process parameters: HMDS flow rate and plasma-generating gas (argon or (Ar +</span></span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">He). The method allows depositing SiCN films at a high speed and a hardness of 20</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">22 GPa.</span>
文摘Gas hydrates and wax are the major flow assurance problems for the transportation of produced hydrocarbons through pipelines.However,in most research works both these two problems are studied separately.Although simultaneous precipitation or deposition of these compounds in pipelines can lead to different mitigation/prevention strategies,the investi-gations in which both these problems are considered simultaneously appeared only recently.There is no information in the literature on the texture/composition and features of decomposition process of mixed wax/hydrate plugs.At the same time,this information could be useful to understand how to treat the problem of formation of these plugs.In this work,three wax/gas hydrate plugs were collected at quasi-static conditions from a water-in-oil emulsion to study their texture,composition and the features of decomposition process.Powder X-ray diffraction and IR(infrared spectroscopy)analyses showed that the plugs consisted of wax and gas hydrate.Thermovolumetric and DSC(Differential Scanning Calorimetry)experiments showed that the main part of gas hydrate in the plugs at the ambient pressure started to decompose at about 268 K.This temperature was higher than the equilibrium temperature of carbon dioxide hydrate at this pressure,indicating that the gas hydrate in the plugs could be effectively preserved at temperatures below the ice melting point(273.2 K).It was found through observation of the hydrate decomposition process in the plugs under the microscope that the gas in the samples released in small bubbles,while the hydrate particles were not visible at this magnification,indicating that the hydrate was indeed highly dispersed in the samples.A residual wax was jelly-like after decomposition of hydrate in all the cases.Rheological experiments showed that the plugs residues after decomposition of the hydrates had higher yield points and viscosities than the initial waxy crude oil origi-nally used for the experiments.
文摘In this work, an analysis of the regularities of the electrolytic dissociation of aryl derivatives of the succinic acid (phenylsuccinic, benzylsuccinic, dibenzylsuccinic and phenyl-2-benzylsuccinic acids) in their dilute (0.0001 - 0.01 mol.dm-3) solutions was carried out with the aid of a new method of determination of the dissociation parameters of weak multibasic organic acids with the “overlapping equilibria” effect previously described by authors. Values of the usual and “partial” degrees of dissociation, the concentrations of all anions, hydrogen ions and undissociated acid molecules, the activity coefficients of all charged dissociation products were calculated. Together with the accurate equations, the simple empirical equations for fast approximate determination of the various dissociation parameters were also suggested.
