Early pregnancy loss,defined as a nonviable intrauterine pregnancy occurring before 12 weeks of gestation,is estimated to affect 25%of clinically diagnosed pregnancies[1].Several demographic,lifestyle,and environmenta...Early pregnancy loss,defined as a nonviable intrauterine pregnancy occurring before 12 weeks of gestation,is estimated to affect 25%of clinically diagnosed pregnancies[1].Several demographic,lifestyle,and environmental risk factors have been reported to associate with the risk of early pregnancy loss,yet the causes of most early pregnancy losses remain elusive;thus,further studies are needed.Perfluorinated compounds(PFCs)are a class of widespread environmental pollutants that can adversely affect human reproductive health.Humans are inevitably exposed to PFCs through diet,water,air and dust.A wealth of epidemiological and toxicological research using a variety of animal models has warned of the persistence,bioaccumulation,and toxicity of PFCs[2].展开更多
Summary What is already known about this topic?The prevalence of adverse pregnancy outcomes(APOs)exhibits a disparity between urban and rural areas,which is commonly associated with various factors,such as demographic...Summary What is already known about this topic?The prevalence of adverse pregnancy outcomes(APOs)exhibits a disparity between urban and rural areas,which is commonly associated with various factors,such as demographic and socio-environmental factors.However,the specific contribution of each factor has not yet been elucidated.What is added by this report?This study demonstrates that the primary factors contributing to urban-rural differences in the prevalence of APOs are population structure,parental age,parity,and regional development.What are the implications for public health practice?Future prevention and control measures should be directed toward considering population structure and regional differences.Accurate interventions will enhance the efficiency of public health services.展开更多
Summary What is already known about this topic?Shanxi Province in northern China has been identified as a region with the highest prevalence of birth defects nationwide.With large amounts of financial support devoted ...Summary What is already known about this topic?Shanxi Province in northern China has been identified as a region with the highest prevalence of birth defects nationwide.With large amounts of financial support devoted for prevention and related interventions for birth defects,huge progress has been made as a 60% decrease in its prevalence was observed from 2009 to 2014.展开更多
Introduction:Macrosomia has short-term and long-term adverse health effects and is thus an important public health concern.Recent decades have witnessed increasing incidence of macrosomia in many countries.Methods:The...Introduction:Macrosomia has short-term and long-term adverse health effects and is thus an important public health concern.Recent decades have witnessed increasing incidence of macrosomia in many countries.Methods:The present study used a large population-based birth cohort study to depict incidence of macrosomia among live births in rural areas of Henan Province of China from 2013 to 2017.Results:Among the 1,262,916 births,82,353 were cases of macrosomia.The overall incidence of all types of macrosomia,of macrosomia with birth weight<4,500 g,and of macrosomia with birth weight≥4,500 g were 6.52%,5.30%,and 1.22%,respectively.From 2013 to 2017,the incidence of macrosomia decreased by 31.3%from 7.96%in 2013 to 5.47%in 2017(X^(2)_(trend)=946.96,P_(trend)<0.001).Male infants and infants≥42 gestational weeks had significantly higher incidence of macrosomia than that of female infants and infants<42 gestational weeks(P<0.001).Conclusion:Gestational weight control through nutrition management and physical activities during pregnancy are needed to reduce incidence of macrosomia.展开更多
Summary What is already known about this topic?Previous studies in western populations have found consistent relationships between adverse childhood experiences and the development of mood and anxiety disorders,especi...Summary What is already known about this topic?Previous studies in western populations have found consistent relationships between adverse childhood experiences and the development of mood and anxiety disorders,especially depressive symptoms in adolescence and adulthood.What is added by this report?This study used a longitudinal design and analytic method to model depressive symptom trajectories from 2011 to 2018 among the middle-aged and elderly in China.This study also investigated the association between adverse childhood experiences and adulthood depressive symptoms in the Chinese population.What are the implications for public health practice?Future public policy could consider early prevention and intervention on adverse childhood experiences to prevent adult depressive symptoms.Besides,it is essential to create safe,stable,and nurturing environments for children’s development.展开更多
基金supported by the National Key Research and Development Program of China[nos.2018YFC1004303 and 2016YFC1000306]the National Natural Science Foundation of China[no.41871360]+1 种基金the Danone Institute China Diet Nutrition Research&Communication Grant[no.DIC2015-05]the National Health Commission Key Laboratory of Birth Defects and Prevention,Henan Province[no.ZD202002].
文摘Early pregnancy loss,defined as a nonviable intrauterine pregnancy occurring before 12 weeks of gestation,is estimated to affect 25%of clinically diagnosed pregnancies[1].Several demographic,lifestyle,and environmental risk factors have been reported to associate with the risk of early pregnancy loss,yet the causes of most early pregnancy losses remain elusive;thus,further studies are needed.Perfluorinated compounds(PFCs)are a class of widespread environmental pollutants that can adversely affect human reproductive health.Humans are inevitably exposed to PFCs through diet,water,air and dust.A wealth of epidemiological and toxicological research using a variety of animal models has warned of the persistence,bioaccumulation,and toxicity of PFCs[2].
文摘Summary What is already known about this topic?The prevalence of adverse pregnancy outcomes(APOs)exhibits a disparity between urban and rural areas,which is commonly associated with various factors,such as demographic and socio-environmental factors.However,the specific contribution of each factor has not yet been elucidated.What is added by this report?This study demonstrates that the primary factors contributing to urban-rural differences in the prevalence of APOs are population structure,parental age,parity,and regional development.What are the implications for public health practice?Future prevention and control measures should be directed toward considering population structure and regional differences.Accurate interventions will enhance the efficiency of public health services.
基金National Natural Science Foundation of China(Grant Number:41871360)National Key Research and Development Program of China(No.2018YFC1004303)National Health Commission Key Laboratory of Birth Defects Prevention,Henan Province(No.ZD202002).
文摘Summary What is already known about this topic?Shanxi Province in northern China has been identified as a region with the highest prevalence of birth defects nationwide.With large amounts of financial support devoted for prevention and related interventions for birth defects,huge progress has been made as a 60% decrease in its prevalence was observed from 2009 to 2014.
基金This study was supported by grants from the National Key Research and Development Program of China(2018YFC1004303)National Natural Science Foundation of China(41871360)and the National Health Commission Key Laboratory of Birth Defects and Prevention,Henan Province(ZD202002).
文摘Introduction:Macrosomia has short-term and long-term adverse health effects and is thus an important public health concern.Recent decades have witnessed increasing incidence of macrosomia in many countries.Methods:The present study used a large population-based birth cohort study to depict incidence of macrosomia among live births in rural areas of Henan Province of China from 2013 to 2017.Results:Among the 1,262,916 births,82,353 were cases of macrosomia.The overall incidence of all types of macrosomia,of macrosomia with birth weight<4,500 g,and of macrosomia with birth weight≥4,500 g were 6.52%,5.30%,and 1.22%,respectively.From 2013 to 2017,the incidence of macrosomia decreased by 31.3%from 7.96%in 2013 to 5.47%in 2017(X^(2)_(trend)=946.96,P_(trend)<0.001).Male infants and infants≥42 gestational weeks had significantly higher incidence of macrosomia than that of female infants and infants<42 gestational weeks(P<0.001).Conclusion:Gestational weight control through nutrition management and physical activities during pregnancy are needed to reduce incidence of macrosomia.
基金from National Natural Science Foundation of China(41871360)the National Key Research and Development Program of China(2018YFC1004303).
文摘Summary What is already known about this topic?Previous studies in western populations have found consistent relationships between adverse childhood experiences and the development of mood and anxiety disorders,especially depressive symptoms in adolescence and adulthood.What is added by this report?This study used a longitudinal design and analytic method to model depressive symptom trajectories from 2011 to 2018 among the middle-aged and elderly in China.This study also investigated the association between adverse childhood experiences and adulthood depressive symptoms in the Chinese population.What are the implications for public health practice?Future public policy could consider early prevention and intervention on adverse childhood experiences to prevent adult depressive symptoms.Besides,it is essential to create safe,stable,and nurturing environments for children’s development.
