The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for centuries.The aging process alters the brain structure that affects functions a...The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for centuries.The aging process alters the brain structure that affects functions and cognitions,but the worsening of such processes contributes to the pathogenesis of neurodegenerative disorders,such as Alzheimer's disease.Beyond these observable,mild morphological shifts,significant functional modifications in neurotransmission and neuronal activity critically influence the aging brain.Understanding these changes is important for maintaining cognitive health,especially given the increasing prevalence of age-related conditions that affect cognition.This review aims to explore the age-induced changes in brain plasticity and molecular processes,differentiating normal aging from the pathogenesis of Alzheimer's disease,thereby providing insights into predicting the risk of dementia,particularly Alzheimer's disease.展开更多
In the paper a referral system to assist the medical experts in the screening/referral of diabetic retinopathy is suggested. The system has been developed by a sequential use of different existing mathematical techniq...In the paper a referral system to assist the medical experts in the screening/referral of diabetic retinopathy is suggested. The system has been developed by a sequential use of different existing mathematical techniques. These techniques involve speeded up robust features(SURF), K-means clustering and visual dictionaries(VD). Three databases are mixed to test the working of the system when the sources are dissimilar. When experiments were performed an area under the curve(AUC) of 0.9343 was attained. The results acquired from the system are promising.展开更多
Electrostatic Rayleigh-Taylor (ERT) mode/instability is studied in a non-uni-form quantum magnetoplasma, whose constituents are electrons and positrons with fraction of ions. The effects of quantum corrections (i.e. B...Electrostatic Rayleigh-Taylor (ERT) mode/instability is studied in a non-uni-form quantum magnetoplasma, whose constituents are electrons and positrons with fraction of ions. The effects of quantum corrections (i.e. Bohm potential and temperature degeneracy) and magnetic field on ERT mode are investigated with astrophysical plasma application. A generalized dispersion relation is deduced under the drift wave approximation. The presence of positron makes the dispersion relation a cubic equation. Different roots of both real and imaginary parts of the RT mode are examined by applying the Cardano’s method of solving the cubic equation. The dispersion relation and the growth rates of RT instability are examined both analytically and numerically with effects of electron and positron density, and magnetic field variations. It is shown that the magnetic field and positron density have stabilizing effectuates on ERT mode while due to electron density the mode becomes unstable. The present work is antici-pated to be of physical relevance in the studies of laboratory laser-produced plasmas as well as in the study of compact magnetized astrophysical objects like white dwarfs.展开更多
文摘The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for centuries.The aging process alters the brain structure that affects functions and cognitions,but the worsening of such processes contributes to the pathogenesis of neurodegenerative disorders,such as Alzheimer's disease.Beyond these observable,mild morphological shifts,significant functional modifications in neurotransmission and neuronal activity critically influence the aging brain.Understanding these changes is important for maintaining cognitive health,especially given the increasing prevalence of age-related conditions that affect cognition.This review aims to explore the age-induced changes in brain plasticity and molecular processes,differentiating normal aging from the pathogenesis of Alzheimer's disease,thereby providing insights into predicting the risk of dementia,particularly Alzheimer's disease.
文摘In the paper a referral system to assist the medical experts in the screening/referral of diabetic retinopathy is suggested. The system has been developed by a sequential use of different existing mathematical techniques. These techniques involve speeded up robust features(SURF), K-means clustering and visual dictionaries(VD). Three databases are mixed to test the working of the system when the sources are dissimilar. When experiments were performed an area under the curve(AUC) of 0.9343 was attained. The results acquired from the system are promising.
文摘Electrostatic Rayleigh-Taylor (ERT) mode/instability is studied in a non-uni-form quantum magnetoplasma, whose constituents are electrons and positrons with fraction of ions. The effects of quantum corrections (i.e. Bohm potential and temperature degeneracy) and magnetic field on ERT mode are investigated with astrophysical plasma application. A generalized dispersion relation is deduced under the drift wave approximation. The presence of positron makes the dispersion relation a cubic equation. Different roots of both real and imaginary parts of the RT mode are examined by applying the Cardano’s method of solving the cubic equation. The dispersion relation and the growth rates of RT instability are examined both analytically and numerically with effects of electron and positron density, and magnetic field variations. It is shown that the magnetic field and positron density have stabilizing effectuates on ERT mode while due to electron density the mode becomes unstable. The present work is antici-pated to be of physical relevance in the studies of laboratory laser-produced plasmas as well as in the study of compact magnetized astrophysical objects like white dwarfs.