Cardiac stromal cells have faced through the years a significant evolution in their definitions concerning their phenotypes,markers,and functions.They are surging to key roles in physiopathology,becoming important tar...Cardiac stromal cells have faced through the years a significant evolution in their definitions concerning their phenotypes,markers,and functions.They are surging to key roles in physiopathology,becoming important targets to be exploited for cardiac repair.In this perspective,we briefly discuss their role in novel therapeutic strategies for enhancing cardiac repair and regeneration.展开更多
We describe a case of a rare congenital heart disorder,scimitar syndrome,diagnosed in an adult woman presenting with dyspnea on exertion,chest pain and recurrent episodes of pulmonary infections.The hallmark of the sy...We describe a case of a rare congenital heart disorder,scimitar syndrome,diagnosed in an adult woman presenting with dyspnea on exertion,chest pain and recurrent episodes of pulmonary infections.The hallmark of the syndrome is the presence of an enlarged anomalous pulmonary vein draining into the inferior vena cava.Speckle tracking echocardiography,including the often-forgotten atrial strain evaluation,is a sensitive parameter that should be routinely used for a better clinical and prognostic evaluation of patients with congenital heart disease(CHD).展开更多
Experiencing various forms of violence in either childhood or adulthood has been associated with cardiovascular disease,both shortly after the event and during follow-up,particularly in women.The coronavirus disease 2...Experiencing various forms of violence in either childhood or adulthood has been associated with cardiovascular disease,both shortly after the event and during follow-up,particularly in women.The coronavirus disease 2019 pandemic has heightened the risk of domestic violence with serious sequelae for mental and cardiovascular health in women,possibly due to several contributing factors,ranging from lockdown,stay at home regulations,job losses,anxiety,and stress.Accordingly,it remains paramount to enforce proactive preventive strategies,at both the family and individual level,maintain a high level of attention to recognize all forms of violence or abuse,and guarantee a multidisciplinary team approach for victims of interpersonal or domestic violence in order to address physical,sexual,and emotional domains and offer a personalized care.展开更多
Introduction Gastrointestinal stromal tumors(GISTs)are neoplasms arising from mesenchymal cells localized into the muscularis propria of the gastrointestinal(GI)tract[1];5%of GISTs are extra-GISTs(EGISTs),as they diff...Introduction Gastrointestinal stromal tumors(GISTs)are neoplasms arising from mesenchymal cells localized into the muscularis propria of the gastrointestinal(GI)tract[1];5%of GISTs are extra-GISTs(EGISTs),as they differently originate from adipose tissue adjacent to the GI tract(omentum and mesentery)or from the pancreas[2].So far,both GISTs and EGISTs have been managed indistinctively by combining surgery,histopathological distinctive features,imaging,and molecular analysis.Moreover.展开更多
基金IC is supported by Grant#RG11916B85CDBF76 from Sapienza UniversityVP is supported by Grant#AR120172B8B543B3 from Sapienza University.FP is supported by Grant#A0375-2020-36621 from Regione Lazio(POR-FESR 2014-2021).
文摘Cardiac stromal cells have faced through the years a significant evolution in their definitions concerning their phenotypes,markers,and functions.They are surging to key roles in physiopathology,becoming important targets to be exploited for cardiac repair.In this perspective,we briefly discuss their role in novel therapeutic strategies for enhancing cardiac repair and regeneration.
文摘We describe a case of a rare congenital heart disorder,scimitar syndrome,diagnosed in an adult woman presenting with dyspnea on exertion,chest pain and recurrent episodes of pulmonary infections.The hallmark of the syndrome is the presence of an enlarged anomalous pulmonary vein draining into the inferior vena cava.Speckle tracking echocardiography,including the often-forgotten atrial strain evaluation,is a sensitive parameter that should be routinely used for a better clinical and prognostic evaluation of patients with congenital heart disease(CHD).
文摘Experiencing various forms of violence in either childhood or adulthood has been associated with cardiovascular disease,both shortly after the event and during follow-up,particularly in women.The coronavirus disease 2019 pandemic has heightened the risk of domestic violence with serious sequelae for mental and cardiovascular health in women,possibly due to several contributing factors,ranging from lockdown,stay at home regulations,job losses,anxiety,and stress.Accordingly,it remains paramount to enforce proactive preventive strategies,at both the family and individual level,maintain a high level of attention to recognize all forms of violence or abuse,and guarantee a multidisciplinary team approach for victims of interpersonal or domestic violence in order to address physical,sexual,and emotional domains and offer a personalized care.
文摘Introduction Gastrointestinal stromal tumors(GISTs)are neoplasms arising from mesenchymal cells localized into the muscularis propria of the gastrointestinal(GI)tract[1];5%of GISTs are extra-GISTs(EGISTs),as they differently originate from adipose tissue adjacent to the GI tract(omentum and mesentery)or from the pancreas[2].So far,both GISTs and EGISTs have been managed indistinctively by combining surgery,histopathological distinctive features,imaging,and molecular analysis.Moreover.
