Over the last years it has started a real revolution in the treatment of chronic hepatitis C. This occurred for the availability of direct-acting antiviral agents that allow to reach sustained virologic response in ap...Over the last years it has started a real revolution in the treatment of chronic hepatitis C. This occurred for the availability of direct-acting antiviral agents that allow to reach sustained virologic response in approximately 90% of cases. In the near future further progress will be achieved with the use of pan-genotypic drugs with high efficacy but without side effects.展开更多
Purpose:The aim of this study was to evaluate the efficacy of a 17-week,3-component lifestyle intervention for enhancing health behaviors during the coronavirus disease 2019(COVID-19)pandemic.Methods:A parallel-group(...Purpose:The aim of this study was to evaluate the efficacy of a 17-week,3-component lifestyle intervention for enhancing health behaviors during the coronavirus disease 2019(COVID-19)pandemic.Methods:A parallel-group(intervention and control)study was conducted amongst 79 airline pilots over a 17-week period during the COVID-19 pandemic.The intervention group(n=38)received a personalized sleep,dietary,and physical activity(PA)program.The control group(n=41)received no intervention.Outcome measures for sleep,fruit and vegetable intake,PA,and subjective health were measured though an online survey before and after the 17-week period.The changes in outcome measures were used to determine the efficacy of the intervention.Results:Significant main effects for time￡group were found for International Physical Activity Questionnaire-walk(p=0.02)and for all other outcome measures(p<0.01).The intervention group significantly improved in sleep duration(p<0.01;d=1.35),Pittsburgh Sleep Quality Index score(p<0.01;d=1.14),moderate-to-vigorous PA(p<0.01;d=1.44),fruit and vegetable intake(p<0.01;d=2.09),Short Form 12v2 physical score(p<0.01;d=1.52),and Short Form 12v2 mental score(p<0.01;d=2.09).The control group showed significant negative change for sleep duration,Pittsburgh Sleep Quality Index score,and Short Form 12v2 mental score(p<0.01).Conclusion:Results provide preliminary evidence that a 3-component healthy sleep,eating,and PA intervention elicit improvements in health behaviors and perceived subjective health in pilots and may improve quality of life during an unprecedented global pandemic.展开更多
文摘Over the last years it has started a real revolution in the treatment of chronic hepatitis C. This occurred for the availability of direct-acting antiviral agents that allow to reach sustained virologic response in approximately 90% of cases. In the near future further progress will be achieved with the use of pan-genotypic drugs with high efficacy but without side effects.
文摘Purpose:The aim of this study was to evaluate the efficacy of a 17-week,3-component lifestyle intervention for enhancing health behaviors during the coronavirus disease 2019(COVID-19)pandemic.Methods:A parallel-group(intervention and control)study was conducted amongst 79 airline pilots over a 17-week period during the COVID-19 pandemic.The intervention group(n=38)received a personalized sleep,dietary,and physical activity(PA)program.The control group(n=41)received no intervention.Outcome measures for sleep,fruit and vegetable intake,PA,and subjective health were measured though an online survey before and after the 17-week period.The changes in outcome measures were used to determine the efficacy of the intervention.Results:Significant main effects for time￡group were found for International Physical Activity Questionnaire-walk(p=0.02)and for all other outcome measures(p<0.01).The intervention group significantly improved in sleep duration(p<0.01;d=1.35),Pittsburgh Sleep Quality Index score(p<0.01;d=1.14),moderate-to-vigorous PA(p<0.01;d=1.44),fruit and vegetable intake(p<0.01;d=2.09),Short Form 12v2 physical score(p<0.01;d=1.52),and Short Form 12v2 mental score(p<0.01;d=2.09).The control group showed significant negative change for sleep duration,Pittsburgh Sleep Quality Index score,and Short Form 12v2 mental score(p<0.01).Conclusion:Results provide preliminary evidence that a 3-component healthy sleep,eating,and PA intervention elicit improvements in health behaviors and perceived subjective health in pilots and may improve quality of life during an unprecedented global pandemic.
