-yopia is the most common refractive disorder. High .myopia affects 27%-33% of all myopic eyes inAsia.1,2 ;The pathologic myopia (PM) is the most severe vision-threatening phenotype of high myopia.3 It is also the s...-yopia is the most common refractive disorder. High .myopia affects 27%-33% of all myopic eyes inAsia.1,2 ;The pathologic myopia (PM) is the most severe vision-threatening phenotype of high myopia.3 It is also the second most common cause of choroidal neovascularization (CNV) in Asia. Unlike age-related macular degeneration (AMD) which mostly effecting elders, PM causes severe vision loss in young adults, resulting in a significant impairment of their working ability.4 PM has become the second leading cause of low vision and blindness particularly among those aged at 40-49 years in some Asia countries.展开更多
基金This study was supported by grants from the China National Basic Research Program (973 Program, No. 2011CB707506), China National Natural Science Foundation (No. 81271030 and No. 81100678), Shanghai Key Basic Research Grant (No. 11JC141601), Shanghai Scholar Leadship Grant (No. 12XD1404100), and Shanghai Committee of Science and Technology Guide Grant (No. 114119a7000).
文摘-yopia is the most common refractive disorder. High .myopia affects 27%-33% of all myopic eyes inAsia.1,2 ;The pathologic myopia (PM) is the most severe vision-threatening phenotype of high myopia.3 It is also the second most common cause of choroidal neovascularization (CNV) in Asia. Unlike age-related macular degeneration (AMD) which mostly effecting elders, PM causes severe vision loss in young adults, resulting in a significant impairment of their working ability.4 PM has become the second leading cause of low vision and blindness particularly among those aged at 40-49 years in some Asia countries.