Noninvasive glucose monitoring(NIGM) techniques based on optical coherence tomography(OCT) are affected by several perturbing factors, including variation of tissue temperature. We first design a temperature contr...Noninvasive glucose monitoring(NIGM) techniques based on optical coherence tomography(OCT) are affected by several perturbing factors, including variation of tissue temperature. We first design a temperature control module integrated with an optical scanning probe to precisely control the temperature of skin tissues. We investigate the influence of temperature on NIGM with OCT by correlation analysis at different depths of in vivo human skin. On average, the relative changes in attenuation coefficient( μt) per 1 °C of temperature lead to 0.30 ± 0.097 mmol/L prediction error of blood glucose concentration. For NIGM measurement methods using optical properties of the tissues, this effect can be taken into account.展开更多
The authors would like to apologize for some mistakes in the letter on Chinese Optics Letters vol. 12, no. 11, page 111701 and wish to make the corrections described below:
基金supported by the National"973"Program of China(No.2010CB327806)the International Science&Technology Cooperation Program of China(No.2010DFB13180)+1 种基金the Medical Instruments and New Medicine Program of Suzhou(No.ZXY2012026)the Foundation Research Project of Jiangsu Province(No.BK20130374)
文摘Noninvasive glucose monitoring(NIGM) techniques based on optical coherence tomography(OCT) are affected by several perturbing factors, including variation of tissue temperature. We first design a temperature control module integrated with an optical scanning probe to precisely control the temperature of skin tissues. We investigate the influence of temperature on NIGM with OCT by correlation analysis at different depths of in vivo human skin. On average, the relative changes in attenuation coefficient( μt) per 1 °C of temperature lead to 0.30 ± 0.097 mmol/L prediction error of blood glucose concentration. For NIGM measurement methods using optical properties of the tissues, this effect can be taken into account.
文摘The authors would like to apologize for some mistakes in the letter on Chinese Optics Letters vol. 12, no. 11, page 111701 and wish to make the corrections described below: