AIM:To evaluate outcomes and determine factors influencing the outcomes of vitrectomy with silicone oil(SO)endotamponade for the management of rhegmatogenous retinal detachment(RRD)complicated by advanced proliferativ...AIM:To evaluate outcomes and determine factors influencing the outcomes of vitrectomy with silicone oil(SO)endotamponade for the management of rhegmatogenous retinal detachment(RRD)complicated by advanced proliferative vitreoretinopathy(PVR).METHODS:This is a retrospective,interventional case series of eyes with PVR grade C associated RRD with or without prior surgery that underwent vitreoretinal surgery and SO tamponade.Eyes with a minimum follow-up of 6mo after SO extraction were included.Eyes were classified into three PVR subgroups according to severity and extension of proliferation.The influence of several preoperative,intraoperative and postoperative factors upon the functional and anatomical outcomes was assessed using multivariate logistic regression analysis.RESULTS:A hundred and one eyes of 101 patients that met the inclusion criteria were studied.Seventy-five of 101 eyes(74.3%)had successful retinal reattachment after one operation.Increased aqueous cell and flare at the first week exam had a statistically significant association with redetachment,recurrent membrane proliferation and keratopathy.Visual acuity improvement was significantly associated with faint postoperative aqueous inflammation values,primary vitrectomy and PVR outside of the posterior pole.CONCLUSION:Although encouraging anatomical and functional outcomes are achieved after vitrectomy and SO tamponade in eyes with RRD complicated by PVR,an increase in aqueous flare or cells at the first week follow-up is most likely to result in postoperative late complications.Primary vitrectomy,PVR associated with minimal posterior pole extension and absent to mild postoperative aqueous inflammation are associated with improved post-operative final visual acuity.展开更多
AIMTo examine the integrity of the ocular surfaces of subjects with and without diabetes with no conjunctival and dry eye signs and symptoms and compare conjunctival impression cytology findings in diabetics with non-...AIMTo examine the integrity of the ocular surfaces of subjects with and without diabetes with no conjunctival and dry eye signs and symptoms and compare conjunctival impression cytology findings in diabetics with non-proliferative and proliferative diabetic retinopathy.展开更多
AIM: To evaluate the effect of hormonal status on aerobic conjunctival flora in women. METHODS: One hundred fifty-eight women [reproductive-aged (n=55), pregnant (n=51), and postmenopausal (n=52)] who admitted to outp...AIM: To evaluate the effect of hormonal status on aerobic conjunctival flora in women. METHODS: One hundred fifty-eight women [reproductive-aged (n=55), pregnant (n=51), and postmenopausal (n=52)] who admitted to outpatient clinic of Obstetrics and Gynecology Department of Denizli State Hospital were enrolled. Age, body-mass index (BMI), obstetric history, cigarette smoking, drug usage, presence of systemic disease, and intraocular pressure (IOP) were recorded for each patient. The samples were taken from the lower fornix with two culture swabs and directly incubated in culture containing 5% sheep blood, eosin-methylene blue and chocolate agar. The other swab specimen was Gram stained. All growths and microscopic results were analyzed. RESULTS: The coagulase-negative Staphylococcus was the predominant organism isolated in the conjunctival samples in both three groups. The aerobic microorganism growth rate for all isolated aerobic organisms revealed no significant change in the three groups (P>0.05). The conjunctival culture positivity rates were similar in the three groups (49% in reproductive-aged, 57% in pregnant and 58% in postmenopausal women) (P>0.05). Age, IOP, BMI, gravidity, parity, cigarette smoking, drug usage, and presence of systemic diseases did not have an effect on culture positivity in three groups. CONCLUSION: Results of this study showed that conjunctival aerobic flora and bacterial colonization did not differ between reproductive-aged, pregnant and postmenopausal women.展开更多
AIM:To evaluate ocular alignment and surgical results of strabismus surgery in neurologically impaired children.· METHODS:Files of 33 neurologically impaired squint children were evaluated.Twelve patients had cer...AIM:To evaluate ocular alignment and surgical results of strabismus surgery in neurologically impaired children.· METHODS:Files of 33 neurologically impaired squint children were evaluated.Twelve patients had cerebral palsy(CP),4 had CP with mental retardation,therest had mental-motor retardation of unknown cause.Cycloplegic refractions,type and angle of strabismus,surgeries performed were recorded.· RESULTS:Mean follow-up was 34.0±16.5 months.Twenty-three patients had esodeviation,the remaining had exodeviation.In 19 patients,angle of deviations measured at different visits were highly variable.Twelve patients with stable angle of deviations or with unstable but high angle deviations had horizontal muscle surgery.Mean horizontal deviation decreased from 43.75±10,69 D to 12.83±8.38D with surgery.· CONCLUSION:In neurologically impaired strabismic children,surgery is effective in patients with stable deviations or unstable but high angle deviations.Decision for surgery should be made after a long follow up period.展开更多
AIM:To assess the impact of macular surgery on the functional and anatomic outcomes of the patients in different grades of epiretinal membrane(ERM).METHODS:Seventy-one eyes of 71 patients who underwent 23-gauge tr...AIM:To assess the impact of macular surgery on the functional and anatomic outcomes of the patients in different grades of epiretinal membrane(ERM).METHODS:Seventy-one eyes of 71 patients who underwent 23-gauge transconjunctival sutureless pars plana vitrectomy for primary isolated ERM were evaluated in this study.RESULTS:There were 38 females(53.5%) and 33 males(46.5%).The average age of the patients was 68.1 y(range 42-89 y).Mean follow up period was 14 mo(range 6-26 mo).The cases were divided into two subgroups of cellophane maculopathy(CM) and macular pucker(MP).An improvement was observed in the postoperative best-corrected visual acuity(BCVA),as well as a decrement in central foveal thickness(CFT) in both groups(both of these being statistically significant;P=0.001).In comparison between two groups,it was found that there was a significant improvement on BCVA and CFT in CM group than MP group(P=0.01).Furthermore,the postoperative fundus findings regarding RPE alterations and macular edema were significantly higher in MP group when compared to the CM group(P=0.01).CONCLUSION:ERM and internal limiting membrane peeling surgery can lead to a significant reduction of CFT and visual improvements in idiopathic ERM.A long-term ERM persistence will cause unrecoverable retinal damage and visual loss.展开更多
文摘AIM:To evaluate outcomes and determine factors influencing the outcomes of vitrectomy with silicone oil(SO)endotamponade for the management of rhegmatogenous retinal detachment(RRD)complicated by advanced proliferative vitreoretinopathy(PVR).METHODS:This is a retrospective,interventional case series of eyes with PVR grade C associated RRD with or without prior surgery that underwent vitreoretinal surgery and SO tamponade.Eyes with a minimum follow-up of 6mo after SO extraction were included.Eyes were classified into three PVR subgroups according to severity and extension of proliferation.The influence of several preoperative,intraoperative and postoperative factors upon the functional and anatomical outcomes was assessed using multivariate logistic regression analysis.RESULTS:A hundred and one eyes of 101 patients that met the inclusion criteria were studied.Seventy-five of 101 eyes(74.3%)had successful retinal reattachment after one operation.Increased aqueous cell and flare at the first week exam had a statistically significant association with redetachment,recurrent membrane proliferation and keratopathy.Visual acuity improvement was significantly associated with faint postoperative aqueous inflammation values,primary vitrectomy and PVR outside of the posterior pole.CONCLUSION:Although encouraging anatomical and functional outcomes are achieved after vitrectomy and SO tamponade in eyes with RRD complicated by PVR,an increase in aqueous flare or cells at the first week follow-up is most likely to result in postoperative late complications.Primary vitrectomy,PVR associated with minimal posterior pole extension and absent to mild postoperative aqueous inflammation are associated with improved post-operative final visual acuity.
文摘AIMTo examine the integrity of the ocular surfaces of subjects with and without diabetes with no conjunctival and dry eye signs and symptoms and compare conjunctival impression cytology findings in diabetics with non-proliferative and proliferative diabetic retinopathy.
文摘AIM: To evaluate the effect of hormonal status on aerobic conjunctival flora in women. METHODS: One hundred fifty-eight women [reproductive-aged (n=55), pregnant (n=51), and postmenopausal (n=52)] who admitted to outpatient clinic of Obstetrics and Gynecology Department of Denizli State Hospital were enrolled. Age, body-mass index (BMI), obstetric history, cigarette smoking, drug usage, presence of systemic disease, and intraocular pressure (IOP) were recorded for each patient. The samples were taken from the lower fornix with two culture swabs and directly incubated in culture containing 5% sheep blood, eosin-methylene blue and chocolate agar. The other swab specimen was Gram stained. All growths and microscopic results were analyzed. RESULTS: The coagulase-negative Staphylococcus was the predominant organism isolated in the conjunctival samples in both three groups. The aerobic microorganism growth rate for all isolated aerobic organisms revealed no significant change in the three groups (P>0.05). The conjunctival culture positivity rates were similar in the three groups (49% in reproductive-aged, 57% in pregnant and 58% in postmenopausal women) (P>0.05). Age, IOP, BMI, gravidity, parity, cigarette smoking, drug usage, and presence of systemic diseases did not have an effect on culture positivity in three groups. CONCLUSION: Results of this study showed that conjunctival aerobic flora and bacterial colonization did not differ between reproductive-aged, pregnant and postmenopausal women.
文摘AIM:To evaluate ocular alignment and surgical results of strabismus surgery in neurologically impaired children.· METHODS:Files of 33 neurologically impaired squint children were evaluated.Twelve patients had cerebral palsy(CP),4 had CP with mental retardation,therest had mental-motor retardation of unknown cause.Cycloplegic refractions,type and angle of strabismus,surgeries performed were recorded.· RESULTS:Mean follow-up was 34.0±16.5 months.Twenty-three patients had esodeviation,the remaining had exodeviation.In 19 patients,angle of deviations measured at different visits were highly variable.Twelve patients with stable angle of deviations or with unstable but high angle deviations had horizontal muscle surgery.Mean horizontal deviation decreased from 43.75±10,69 D to 12.83±8.38D with surgery.· CONCLUSION:In neurologically impaired strabismic children,surgery is effective in patients with stable deviations or unstable but high angle deviations.Decision for surgery should be made after a long follow up period.
文摘AIM:To assess the impact of macular surgery on the functional and anatomic outcomes of the patients in different grades of epiretinal membrane(ERM).METHODS:Seventy-one eyes of 71 patients who underwent 23-gauge transconjunctival sutureless pars plana vitrectomy for primary isolated ERM were evaluated in this study.RESULTS:There were 38 females(53.5%) and 33 males(46.5%).The average age of the patients was 68.1 y(range 42-89 y).Mean follow up period was 14 mo(range 6-26 mo).The cases were divided into two subgroups of cellophane maculopathy(CM) and macular pucker(MP).An improvement was observed in the postoperative best-corrected visual acuity(BCVA),as well as a decrement in central foveal thickness(CFT) in both groups(both of these being statistically significant;P=0.001).In comparison between two groups,it was found that there was a significant improvement on BCVA and CFT in CM group than MP group(P=0.01).Furthermore,the postoperative fundus findings regarding RPE alterations and macular edema were significantly higher in MP group when compared to the CM group(P=0.01).CONCLUSION:ERM and internal limiting membrane peeling surgery can lead to a significant reduction of CFT and visual improvements in idiopathic ERM.A long-term ERM persistence will cause unrecoverable retinal damage and visual loss.