Dielectrophoresis （DEP） is one of the most popular techniques for bio-particle manipulation in microfluidic systems. Traditional calculation of dielectrophoretic forces of single particle based on the approximation ...Dielectrophoresis （DEP） is one of the most popular techniques for bio-particle manipulation in microfluidic systems. Traditional calculation of dielectrophoretic forces of single particle based on the approximation of equivalent dipole moment （EDM） cannot be directly applied on the dense particle interactions in an electrical field. The Maxwell stress tensor （MST） method is strictly accurate in the theory for dielectrophoretic forces of particle interaction, but the cumbersome and complicated numerical computation greatly limits its practical applications. A novel iterative dipole moment （IDM） method is pre- sented in this work for calculating the dielectrophoretic forces of particle-particle inter- actions. The accuracy, convergence, and simplicity of the IDM are confirmed by a series of examples of two-particle interaction in a DC/AC electrical field. The results indicate that the IDM is able to calculate the DEP particle interaction forces in good agreement with the MST method. The IDM is a purely analytical operation and does not require complicated numerical computation for solving the differential equations of an electrical field while the particle is moving.展开更多
The microfiuidic system is a multi-physics interaction field that has at- tracted great attention. The electric double layers and electroosmosis are important flow-electricity interaction phenomena. This paper present...The microfiuidic system is a multi-physics interaction field that has at- tracted great attention. The electric double layers and electroosmosis are important flow-electricity interaction phenomena. This paper presents a thickness-averaged model to solve three-dimensional complex electroosmotic flows in a wide-shallow microchan- nel/chamber combined （MCC） chip based on the Navier-Stokes equations for the flow field and the Poisson equation to the electric field. Behaviors of the electroosmotic flow, the electric field, and the pressure are analyzed. The quantitative effects of the wall charge density （or the zeta potential） and the applied electric field on the electroosmotic flow rate are investigated. The two-dimensional thickness-averaged flow model greatly simplifies the three-dimensional computation of the complex electroosmotic flows, and correctly reflects the electrookinetic effects of the wall charge on the flow. The numerical results indicate that the electroosmotic flow rate of the thickness-averaged model agrees well with that of the three-dimensional slip-boundary flow model. The flow streamlines and pressure distribution of these two models are in qualitative agreement.展开更多
基金Project supported by the National Natural Science Foundation of China(No.11172111)
文摘Dielectrophoresis （DEP） is one of the most popular techniques for bio-particle manipulation in microfluidic systems. Traditional calculation of dielectrophoretic forces of single particle based on the approximation of equivalent dipole moment （EDM） cannot be directly applied on the dense particle interactions in an electrical field. The Maxwell stress tensor （MST） method is strictly accurate in the theory for dielectrophoretic forces of particle interaction, but the cumbersome and complicated numerical computation greatly limits its practical applications. A novel iterative dipole moment （IDM） method is pre- sented in this work for calculating the dielectrophoretic forces of particle-particle inter- actions. The accuracy, convergence, and simplicity of the IDM are confirmed by a series of examples of two-particle interaction in a DC/AC electrical field. The results indicate that the IDM is able to calculate the DEP particle interaction forces in good agreement with the MST method. The IDM is a purely analytical operation and does not require complicated numerical computation for solving the differential equations of an electrical field while the particle is moving.
基金Project supported by the National Natural Science Foundation of China （No. 11172111） and the Ph.D. Programs Foundation of Ministry of Education of China （No. 20090142120007）
文摘The microfiuidic system is a multi-physics interaction field that has at- tracted great attention. The electric double layers and electroosmosis are important flow-electricity interaction phenomena. This paper presents a thickness-averaged model to solve three-dimensional complex electroosmotic flows in a wide-shallow microchan- nel/chamber combined （MCC） chip based on the Navier-Stokes equations for the flow field and the Poisson equation to the electric field. Behaviors of the electroosmotic flow, the electric field, and the pressure are analyzed. The quantitative effects of the wall charge density （or the zeta potential） and the applied electric field on the electroosmotic flow rate are investigated. The two-dimensional thickness-averaged flow model greatly simplifies the three-dimensional computation of the complex electroosmotic flows, and correctly reflects the electrookinetic effects of the wall charge on the flow. The numerical results indicate that the electroosmotic flow rate of the thickness-averaged model agrees well with that of the three-dimensional slip-boundary flow model. The flow streamlines and pressure distribution of these two models are in qualitative agreement.
