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Sonodynamic therapy for the treatment of atherosclerosis
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作者 Yan Zhang Ying Yang +7 位作者 Yudi Feng Xueyan Gao Liping Pei Xiaopan Li Bingxin Gao Lin Liu Chengzeng Wang Shuochen Gao 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2024年第5期666-677,共12页
Atherosclerosis(AS)is a chronic inflammatory disease of large and medium-sized arteries that leads to ischemic heart disease,stroke,and peripheral vascular disease.Despite the current treatments,mortality and disabili... Atherosclerosis(AS)is a chronic inflammatory disease of large and medium-sized arteries that leads to ischemic heart disease,stroke,and peripheral vascular disease.Despite the current treatments,mortality and disability still remain high.Sonodynamic therapy(SDT),a non-invasive and localized methodology,has been developed as a promising new treatment for inhibiting atherosclerotic progression and stabilizing plaques.Promising progress has been made through cell and animal assays,as well as clinical trials.For example,the effect of SDT on apoptosis and autophagy of cells in AS,especially macrophages,and the concept of non-lethal SDT has also been proposed.In this review,we summarize the ultrasonic parameters and known sonosensitizers utilized in SDT for AS;we elaborate on SDT's therapeutic effects and mechanisms in terms of macrophages,T lymphocytes,neovascularization,smooth muscle cells,lipid,extracellular matrix and efferocytosis within plaques;additionally,we discuss the safety of SDT.A comprehensive summary of the confirmed effects of SDT on AS is conducted to establish a framework for future researchers. 展开更多
关键词 ATHEROSCLEROSIS Sonodynamic therapy Sonosensitizer ULTRASOUND Reactive oxygen species
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Revealing the role of honokiol in human glioma cells by RNA-seq analysis
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作者 YUNBAO GUO XU LIU +5 位作者 QI XU XIAOTONG ZHOU JIAWEI LIU YANYAN XU YAN LU HAIYAN LIU 《BIOCELL》 SCIE 2024年第6期945-958,共14页
Background:Glioma is a kind of tumor that easily deteriorates and originates from glial cells in nerve tissue.Honokiol is a bisphenol compound that is an essential monomeric compound extracted from the roots and bark ... Background:Glioma is a kind of tumor that easily deteriorates and originates from glial cells in nerve tissue.Honokiol is a bisphenol compound that is an essential monomeric compound extracted from the roots and bark of Magnoliaceae plants.It also has anti-infection,antitumor,and immunomodulatory effects.In this study,we found that honokiol induces cell apoptosis in the human glioma cell lines U87-MG and U251-MG.However,the mechanism through which honokiol regulates glioma cell apoptosis is still unknown.Methods:We performed RNA-seq analysis of U251-MG cells treated with honokiol and control cells.Protein-protein interaction(PPI)network analysis was performed,and the 10 top hub unigenes were examined via real-time quantitative PCR.Furthermore,MAPK signaling and ferroptosis were detected via western blotting.Results:332 differentially expressed genes(DEGs)were found,comprising 163 increased and 169 decreased genes.Analysis of the DEGs revealed that various biological processes were enriched,including‘response to hypoxia’,‘cerebellum development cellular response to hypoxia,’‘iron ion binding,’‘oxygen transporter activity,’‘oxygen binding,’‘ferric iron binding,’and‘structural constituent of cytoskeleton.’Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis revealed that the DEGs were enriched in the following pathways:‘mitogen-activated protein kinases(MAPK)’,‘Hypoxia-inducible factor 1(HIF-1)’,‘ferroptosis,’‘Peroxisome proliferator-activated receptor(PPAR),’‘Phosphatidylinositol-4,5-bisphosphate 3-kinase(PI3K)-protein kinase B(Akt),’and‘phagosome.’Among these pathways,the MAPK signaling pathway and ferroptosis were verified.Conclusion:This study revealed the potential mechanism by which honokiol induces apoptosis and provided a comprehensive analysis of DEGs in honokiol-treated U251-MG cells and the associated signaling pathways.These data could lead to new ideas for future research and therapy for patients with glioma. 展开更多
关键词 Human glioma HONOKIOL RNA-SEQ APOPTOSIS Ferroptosis MAPK
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Energy-efficient joint UAV secure communication and 3D trajectory optimization assisted by reconfigurable intelligent surfaces in the presence of eavesdroppers
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作者 Huang Hailong Mohsen Eskandari +1 位作者 Andrey V.Savkin Wei Ni 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第1期537-543,共7页
We consider a scenario where an unmanned aerial vehicle(UAV),a typical unmanned aerial system(UAS),transmits confidential data to a moving ground target in the presence of multiple eavesdroppers.Multiple friendly reco... We consider a scenario where an unmanned aerial vehicle(UAV),a typical unmanned aerial system(UAS),transmits confidential data to a moving ground target in the presence of multiple eavesdroppers.Multiple friendly reconfigurable intelligent surfaces(RISs) help to secure the UAV-target communication and improve the energy efficiency of the UAV.We formulate an optimization problem to minimize the energy consumption of the UAV,subject to the mobility constraint of the UAV and that the achievable secrecy rate at the target is over a given threshold.We present an online planning method following the framework of model predictive control(MPC) to jointly optimize the motion of the UAV and the configurations of the RISs.The effectiveness of the proposed method is validated via computer simulations. 展开更多
关键词 Unmanned aerial systems(UASs) Unmanned aerial vehicle(UAV) Communication security Eaves-dropping Reconfigurable intelligent surfaces(RIS) Autonomous navigation and placement Path planning Model predictive control
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Variation in the Composition of the Essential Oil of Commercial Salvia officinalis L.Leaves Samples from Different Countries
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作者 Ain Raal Anne Orav +4 位作者 Tetiana Ilina Alla Kovalyova Taras Koliadzhyn Yuliia Avidzba Oleh Koshovyi 《Phyton-International Journal of Experimental Botany》 SCIE 2024年第8期2051-2062,共12页
Salvia officinalis L.(Lamiaceae)leaves and its essential oil is used for mouth and throat disorders,skin disorders,minor wounds,and gastrointestinal disorders,and is widely used worldwide.The research aimed to conduct... Salvia officinalis L.(Lamiaceae)leaves and its essential oil is used for mouth and throat disorders,skin disorders,minor wounds,and gastrointestinal disorders,and is widely used worldwide.The research aimed to conduct a comparative study of the composition of S.officinalis essential oils from commercial samples,and their main chemotypes.The volatile constituents from S.officinalis leaves were investigated using gas chromatography(GC).The commercial samples of sage leaves were obtained from retail pharmacies in nine mainly European countries.The yield of essential oil in S.officinalis commercial leaves was between 10.0 and 24.8 mL/kg.The principal components(>5%)among the main identified 25 compounds were 1,8-cineole(8.3%–45.3%),α-thujone(3.0%–34.0%),сamphor(11.3%–29.3%),β-thujone(1.5%–12.9%),viridiflorol(1.1%–10.4%),camphene(2.6%–7.1%),andα-pinene(1.3%–5.8%).In seven(Estonia,England,France,Hungary,Belgium,Ukraine,Georgia)samplesα-thujone dominated.Four samples(Estonia,Georgia,England,Hungary)belong to the most common chemotypeα-thujone>camphor>1,8-cineole.Eight chemotypes of S.officinalis essential oils have been found.Toxic thujones are widespread compounds among them. 展开更多
关键词 SAGE TERPENOIDS CHEMOTYPES thujone TOXICITY
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Perceptions and Controversies on Cholera in the Traditional Chinese Medicine Field in the Late Qing Dynasty
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作者 GUO Shiqiang WU Haohuan WU Yinghua 《Chinese Medicine and Culture》 2024年第2期143-151,共9页
At the beginning of the initial cholera outbreak in China,Wang Qingren(王清任),after years of clinical trials,became an early representative who discovered the infectious characteristics and observed the course of cho... At the beginning of the initial cholera outbreak in China,Wang Qingren(王清任),after years of clinical trials,became an early representative who discovered the infectious characteristics and observed the course of cholera in the field of traditional Chinesse medicine(TCM).Kou Langao(寇兰皋)and Xu Zimo(徐子默),both medical practitioners,constructed a diagnosis and treatment system for cholera with cold patterns under the theory of typhoid.They represented“School of Cholera with Cold Patterns”(SCCP).In the 1860s,with the influence of Wang Shixiong’s(王士雄)studies on the nature of cholera under the theory of epidemic febrile disease,the“School of Cholera with Heated Patterns”(SCHP)prevailed thereafter.The two schools complemented each other in theories and contributed to the integrity of TCM in cholera diagnosis and treatment.By reviewing previous literature,books,clinical cases,and historical materials in medical field,this article aims 1)to summarise the influence of TCM on the cognitive development towards cholera in the late Qing dynasty;2)to explore the origin of the controversy between SCCP and SCHP from historical evidence;3)to summarize the historical lessons from the debate over cholera in TCM based on the principle of treatment based on pattern identification,and offer suggestions for the current prevention and treatment of new diseases using TCM. 展开更多
关键词 Traditional Chinese medicine CHOLERA School of Cholera with Cold Patterns School of Cholera with Heated Patterns Wang Shixiong Xu Zimo
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3D Localization for Multiple AUVs in Anchor-Free Environments by Exploring the Use of Depth Information
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作者 Yichen Li Wenbin Yu Xinping Guan 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第4期1051-1053,共3页
Dear Editor,This letter investigates the cooperative localization problem for multiple autonomous underwater vehicles(AUVs)in underwater anchor-free environments,where AUV localization errors grow without bound due to... Dear Editor,This letter investigates the cooperative localization problem for multiple autonomous underwater vehicles(AUVs)in underwater anchor-free environments,where AUV localization errors grow without bound due to the accumulated errors in inertial measurements(termed accumulated errors hereafter)and the lack of anchors(with known positions). 展开更多
关键词 AUVS UNDERWATER hereafter
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Distributed Economic MPC for Synergetic Regulation of the Voltage of an Island DC Micro-Grid
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作者 Yi Zheng Yanye Wang +2 位作者 Xun Meng Shaoyuan Li Hao Chen 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第3期734-745,共12页
In this paper,distributed model predictive control(DMPC) for island DC micro-grids(MG) with wind/photovoltaic(PV)/battery power is proposed,which coordinates all distributed generations(DG) to stabilize the bus voltag... In this paper,distributed model predictive control(DMPC) for island DC micro-grids(MG) with wind/photovoltaic(PV)/battery power is proposed,which coordinates all distributed generations(DG) to stabilize the bus voltage together with the insurance of having computational efficiency under a real-time requirement.Based on the feedback of the bus voltage,the deviation of the current is dispatched to each DG according to cost over the prediction horizon.Moreover,to avoid the excessive fluctuation of the battery power,both the discharge-charge switching times and costs are considered in the model predictive control(MPC) optimization problems.A Lyapunov constraint with a time-varying steady-state is designed in each local MPC to guarantee the stabilization of the entire system.The voltage stabilization of the MG is achieved by this strategy with the cooperation of DGs.The numeric results of applying the proposed method to a MG of the Shanghai Power Supply Company shows the effectiveness of the distributed economic MPC. 展开更多
关键词 Distributed model predictive control(DMPC) Lyapunovbased model predictive control micro-grid(MG) voltage control
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Evolution and Prospects of Russia’s“Turn to the East”
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作者 Li Ziguo 《China International Studies》 2024年第4期71-95,共25页
With the escalation of the Ukraine crisis,Russia’s policy of“Turn to the East”has evolved into“Turn to the Non-West”at an accelerated pace.Involving both a shift of focus in diplomacy and economics and the“de-We... With the escalation of the Ukraine crisis,Russia’s policy of“Turn to the East”has evolved into“Turn to the Non-West”at an accelerated pace.Involving both a shift of focus in diplomacy and economics and the“de-Westernization”in financial and ideological areas,it has become a strategy to break through Western diplomatic and economic blockade.The transition will continue in the medium term,but adjustments or twists and turns are likely under the influence of internal and external factors. 展开更多
关键词 EAST TURNS RUSSIA
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Neural Dynamics for Cooperative Motion Control of Omnidirectional Mobile Manipulators in the Presence of Noises: A Distributed Approach
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作者 Yufeng Lian Xingtian Xiao +3 位作者 Jiliang Zhang Long Jin Junzhi Yu Zhongbo Sun 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第7期1605-1620,共16页
This paper presents a distributed scheme with limited communications, aiming to achieve cooperative motion control for multiple omnidirectional mobile manipulators(MOMMs).The proposed scheme extends the existing singl... This paper presents a distributed scheme with limited communications, aiming to achieve cooperative motion control for multiple omnidirectional mobile manipulators(MOMMs).The proposed scheme extends the existing single-agent motion control to cater to scenarios involving the cooperative operation of MOMMs. Specifically, squeeze-free cooperative load transportation is achieved for the end-effectors of MOMMs by incorporating cooperative repetitive motion planning(CRMP), while guiding each individual to desired poses. Then, the distributed scheme is formulated as a time-varying quadratic programming(QP) and solved online utilizing a noise-tolerant zeroing neural network(NTZNN). Theoretical analysis shows that the NTZNN model converges globally to the optimal solution of QP in the presence of noise. Finally, the effectiveness of the control design is demonstrated by numerical simulations and physical platform experiments. 展开更多
关键词 Cooperative motion control noise-tolerant zeroing neural network(NTZNN) omnidirectional mobile manipulator(OMM) repetitive motion planning
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Meiotic nuclear divisions 1 suppresses the proliferation and invasion of pancreatic cancer cells via regulating H2A.X variant histone
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作者 DONGQIN WANG YAN SHI +8 位作者 ZHIQIANG WANG JING ZHANG LUYAO WANG HONGYU MA SHUHUA SHI XIAOFU LIAN HUA HUANG XIAOJING WANG CHAOQUN LIAN 《BIOCELL》 SCIE 2024年第1期111-122,共12页
Introduction:Among all malignant tumors of the digestive system,pancreatic carcinoma exhibits the highest mortality rate.Currently,prevention and effective treatment are urgent issues that need to be addressed.Methods... Introduction:Among all malignant tumors of the digestive system,pancreatic carcinoma exhibits the highest mortality rate.Currently,prevention and effective treatment are urgent issues that need to be addressed.Methods:The study focused on meiotic nuclear divisions 1(MND1),integrating data from the Gene Expression Profiling Interactive Analysis(GEPIA)database with prognostic survival analysis.Simultaneously,experiments at cellular level were employed to demonstrate the effect of MND1 on the proliferation and migration of PC.The small-molecule inhibitor of MND1 was used to suppress the migration of PC cells by knocking down MND1 using small interfering RNA(siRNA)in Patu-8988 and Panc1 cell lines.Results:The results of Cell Counting Kit-8 indicated that the suppression of MND1 resulted in a decrease in cell proliferation.Wound healing and Transwell assays revealed that MND1 knockdown reduced cell migration and invasion.Flow cytometry revealed that inhibiting MND1 hindered the cell cycle.Furthermore,MND1 could stimulate the proliferation,migration,and invasion of Patu-8988 and Panc1 cells by increasing the expression of MND1.Notably,MND1 had a positive effect on H2AFX expression in PC cells.Elevated MND1 expression suggests the low overall survival rate of individuals diagnosed with PC.Conclusion:These findings suggest that MND1 has the potential to be a gene with the ability to accurately diagnose and treat PC. 展开更多
关键词 Pancreatic carcinoma MND1 H2AFX Cell cycle
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The Oral Health Status of Person with Special Needs in Kumasi
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作者 Ama Agyeibea Amuasi Alexander Oti-Acheampong +1 位作者 Victoria N. A. Boadu Lord J. J. Gowans 《Open Journal of Stomatology》 2024年第1期14-31,共18页
Background: The most prevalent non-communicable disease worldwide is oral health-related disease, with dental caries and periodontal conditions being common. Oral health status significantly impacts overall health and... Background: The most prevalent non-communicable disease worldwide is oral health-related disease, with dental caries and periodontal conditions being common. Oral health status significantly impacts overall health and quality of life. Barriers to dental care affect children with special needs. This study evaluates the oral health status and treatment requirements of people with special needs. Methodology: This descriptive cross-sectional study in Kumasi, Ghana examined oral health status among people, 121 children with special needs over two months, in June-July 2022. Dental caries, periodontal changes, malocclusion, and trauma were assessed. The data was analyzed using SPSS 20.0. Results: The oral health status among people with special needs in this study was generally moderate, with a range from very good to very poor. The prevalence of dental caries was 37%, with a mean DMFT score of 2.82. Periodontal health showed unsatisfactory indicators such as mobile teeth, poor gingival health, high plaque scores, and the presence of halitosis. Conclusion: This descriptive study aimed to provide baseline data on the oral health status of special needs students in Kumasi, addressing the lack of knowledge in this area. It highlighted the importance of dental care in maintaining good oral health and overall well-being in individuals with special needs. Coordinated efforts by dental professionals are needed to provide dental health education and preventive interventions for these children. 展开更多
关键词 Special Needs Oral Health Dental Caries Periodontal Diseases MALOCCLUSION
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Knowledge and the Attitude on the Use of Mouthwash among Two Selected Senior High Schools in Kumasi
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作者 Ama Agyeibea Amuasi Kwame A. Koranteng Joseph Abu-Sakyi 《Open Journal of Stomatology》 2024年第5期218-234,共17页
BACKGROUND: The route of most systemic diseases begins in the oral cavity. Oral health knowledge of mouthwashes and their uses is indispensable for the general population and especially adolescents. The use of mouthwa... BACKGROUND: The route of most systemic diseases begins in the oral cavity. Oral health knowledge of mouthwashes and their uses is indispensable for the general population and especially adolescents. The use of mouthwash by adolescents can be a beneficial adjunct to their oral hygiene routine, providing additional protection against dental diseases and promoting fresher breath. Overuse or misuse of mouthwash, particularly those containing alcohol or other potentially irritating ingredients, may lead to adverse effects such as oral mucosal irritation, dry mouth, or alteration of the oral microbiome. OBJECTIVES: To determine the knowledge, attitude, and use of mouthwash among senior high school students in Kumasi. METHODOLOGY: 120 students responded to a standard questionnaire by a convenient sample technique. The Statistical Package for Social Sciences (SPSS) 22.0 and MS Excel were used for data management and analysis. The results of the study were presented using tables, bar charts, and pie chart. RESULTS: The ages of the respondents ranged from 14 to 20 years. Out of the 120 participants, 71 students that represent 59.2% of the total, used mouthwash. Majority of the participants (63%) utilized a mouthwash after brushing their teeth. 49% of the participants reported using mouthwash to address halitosis, 37% used it to combat periodontal disease, and 10% used it for relief from a sore throat. CONCLUSION: In general, most of the participants who use mouthwash had excellent knowledge and a positive attitude toward the use of mouthwash. 展开更多
关键词 Oral Cavity MOUTHWASH Plaque Biofilm GINGIVITIS Convenient Sampling
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Prevalence of Dental Anomalies among Patients Who Report to the Komfo Anokye Teaching Hospital’s Orthodontic Clinic
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作者 Ama Agyeibea Amuasi Daniel K. Sabbah +1 位作者 Alexander Oti-Achempong Rahman N. Mamah 《Open Journal of Stomatology》 2024年第2期103-117,共15页
BACKGROUND: Dental anomalies are variations from the established well-known general anatomy and morphology of the tooth as a result of disturbances during tooth formation. They can be developmental, congenital, or acq... BACKGROUND: Dental anomalies are variations from the established well-known general anatomy and morphology of the tooth as a result of disturbances during tooth formation. They can be developmental, congenital, or acquired and may be localized to a single tooth or involve systemic conditions. AIM: To evaluate the prevalence of dental anomalies in patients who report to the Komfo Anokye Teaching Hospital (KATH) dental clinics. METHOD: A descriptive cross-sectional design was used with a sample size of 92 patients aged 18 or older, obtained through convenience sampling. Data analysis was performed using SPSS version 26.0. RESULTS: The study included 92 patients aged 18 to 72 years, with 47.8% males and 52.2% females. Dental anomalies were observed in 51.1% of participants, with a higher prevalence in females (55.3%). The most common anomalies were diastema (48.3%), impacted teeth (22.0%), dilaceration (11.9%), and peg-shaped lateral teeth (6.8%). CONCLUSION: This study highlights the importance of conducting thorough dental examinations to identify and address dental anomalies, which may have implications for treatment. Early detection and correction of these anomalies are crucial to prevent future complications. 展开更多
关键词 Dental Anomalies PREVALENCE Impacted Teeth Dilaceration
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“Luminous Conflicts:Navigating Architecture,Light,and Visitor Experience in Museums”:The Case of Yale Center for British Art
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作者 Charalampia N.Dimitropoulou Andreas Giacumacatos 《Journal of Civil Engineering and Architecture》 2024年第9期415-422,共8页
The architectural design of the YCBA(Yale Center for British Art)exemplifies Kahn’s exploration of light as a transformative element.However,preserving sensitive materials within the museum challenges the building’s... The architectural design of the YCBA(Yale Center for British Art)exemplifies Kahn’s exploration of light as a transformative element.However,preserving sensitive materials within the museum challenges the building’s original intent.The potential harm caused by light necessitates control measures,potentially compromising the intended luminous ambiance envisioned by Kahn.A comprehensive survey revealed a strong preference for natural light in the museum environment.Visitors appreciated the ethereal qualities and heightened engagement with exhibits facilitated by natural light.This research critically examines the balance between architectural vision,preservation imperatives,and visitor expectations,highlighting the museum space as a dynamic field of action.The architectural elements,interior configuration,lighting,and movement are in constant harmony and conflict.This investigation contributes to a deeper understanding of the relationship between architecture,light,the museum experience,and knowledge.It underscores the importance of considering preservation,design,and visitor preferences when balancing these elements in museums. 展开更多
关键词 ARCHITECTURE LIGHT VISITORS museum experience
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Assessing the Levels of Clinical Reasoning Skills Using Self-Assessment of Clinical Reflection and Reasoning in Undergraduate Nursing Students: A Descriptive Comparative Study
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作者 Omero G. Mwale Patricia K. Mukwato Marjorie K. Makukula‡ 《Open Journal of Nursing》 2024年第7期283-297,共15页
Background: Clinical reasoning is a critical cognitive skill that enables undergraduate nursing students to make clinically sound decisions. A lapse in clinical reasoning can result in unintended harm to patients. The... Background: Clinical reasoning is a critical cognitive skill that enables undergraduate nursing students to make clinically sound decisions. A lapse in clinical reasoning can result in unintended harm to patients. The aim of the study was to assess and compare the levels of clinical reasoning skills between third year and fourth year undergraduate nursing students. Methods: The study utilized a descriptive comparative research design, based on the positivism paradigm. 410 undergraduate nursing students were systematically sampled and recruited into the study. The researchers used the Self-Assessment of Clinical Reflection and Reasoning questionnaire to collect data on clinical reasoning skills from third- and fourth-year nursing students while adhering to ethical principles of human dignity. Descriptive statistics were done to analyse the level of clinical reasoning and an independent sample t-test was performed to compare the clinical reasoning skills of the student. A p value of 0.05 was accepted. Results: The results of the study revealed that the mean clinical reasoning scores of the undergraduate nursing students were knowledge/theory application (M = 3.84;SD = 1.04);decision-making based on experience and evidence (M = 4.09;SD = 1.01);dealing with uncertainty (M = 3.93;SD = 0.87);reflection and reasoning (M = 3.77;SD = 3.88). The mean difference in clinical reasoning skills between third- and fourth-year undergraduate nursing students was not significantly different from an independent sample t-test scores (t = −1.08;p = 0.28);(t = −0.29;p = 0.73);(t = 1.19;p = 0.24);(t = −0.57;p = 0.57). Since the p-value is >0.05, the null hypothesis (H0) “there is no significantno significant difference in clinical reasoning between third year and fourth year undergraduate nursing students”, was accepted. Conclusion: This study has shown that the level of clinical reasoning skills of the undergraduate nursing students was moderate to low. This meant that the teaching methods have not been effective to improve the students clinical reasoning skills. Therefore, the training institutions should revise their curriculum by incorporating new teaching methods like simulation to enhance students’ clinical reasoning skills. In conclusion, evaluating clinical reasoning skills is crucial for addressing healthcare issues, validating teaching methods, and fostering continuous improvement in nursing education. 展开更多
关键词 Clinical Competences Clinical Reasoning Skills Undergraduate Nursing Student
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Theory and verification of moiréfringes for x-ray three-phase grating interferometer
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作者 单雨征 葛永帅 +5 位作者 杨君 郭大育 蔡学宝 刘晓珂 侯晓文 郭金川 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第5期532-540,共9页
Dual-phase and three-phase grating x-ray interference is a promising new technique for grating-based x-ray differential phase contrast imaging.Dual-phase grating interferometers have been relatively completely studied... Dual-phase and three-phase grating x-ray interference is a promising new technique for grating-based x-ray differential phase contrast imaging.Dual-phase grating interferometers have been relatively completely studied and discussed.In this paper,the corresponding imaging fringe formula of the three-phase grating interferometer is provided.At the same time,the similarities and differences between the three-phase grating interferometer and the dual-phase grating interferometer are investigated and verified,and that the three-phase grating interferometer can produce large-period moiréfringes without using the analyzing grating is demonstrated experimentally.Finally,a simple method of designing three-phase grating and multi-grating imaging systems from geometric optics based on the thin-lens theory of gratings is presented.These theoretical formulas and experimental results provide optimization tools for designing three-phase grating interferometer systems. 展开更多
关键词 x-ray phase contrast phase grating moiréfringe
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Contingency management strategies of the Nursing Department in centralized rescue of patients with coronavirus disease 2019 被引量:2
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作者 Huafen Wang Jiehui Feng +8 位作者 Lewen Shao Jianhua Wei Xiaoyan Wang Xiaowei Xu Rongya Shao Meiyun Zhang Jiangjuan He Xuehong Zhao Tingbo Liang 《International Journal of Nursing Sciences》 CSCD 2020年第2期139-142,共4页
Objectives:This article aims to summarize a series of contingency management strategies of the Nursing Department in the centralized treatment of patients with coronavirus disease 2019(COVID-19).Methods:The strategies... Objectives:This article aims to summarize a series of contingency management strategies of the Nursing Department in the centralized treatment of patients with coronavirus disease 2019(COVID-19).Methods:The strategies of the Nursing Department included an early warning for prevention and control,taking functions of vertically commanding and horizontally coordinating,and reasonably allocating nursing workforce,to facilitate centralized treatment work in the in-hospital fever clinic,isolation wards and ICU,and referral and admission of critical patients.Five special groups were established in charge of training and examination,management and supervision,psychological support,logistical support,and reporting and publicity,respectively.Results:It was achieved that no deaths from critical patients and no medical staff,no other patients were infected.Conclusion:Through the implementation of these strategies,safe and efficient centralized treatment was ensured timely,orderly and sustainably. 展开更多
关键词 Contingency management COVID-19 Infectious disease control Nursing administration research Public health emergencies
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High-intensity swimming alleviates nociception and neuroinflammation in a mouse model of chronic postischemia pain by activating the resolvin E1-chemerin receptor 23 axis in the spinal cord 被引量:2
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作者 Xin Jia Ziyang Li +3 位作者 Xiafeng Shen Yu Zhang Li Zhang Ling Zhang 《Neural Regeneration Research》 SCIE CAS CSCD 2023年第11期2535-2544,共10页
Physical exe rcise effectively alleviates chronic pain associated with complex regional pain syndrome type-Ⅰ.However,the mechanism of exe rcise-induced analgesia has not been clarified.Recent studies have shown that ... Physical exe rcise effectively alleviates chronic pain associated with complex regional pain syndrome type-Ⅰ.However,the mechanism of exe rcise-induced analgesia has not been clarified.Recent studies have shown that the specialized pro-resolving lipid mediator resolvin E1 promotes relief of pathologic pain by binding to chemerin receptor 23 in the nervous system.However,whether the resolvin E1-chemerin receptor 23 axis is involved in exercise-induced analgesia in complex regional pain syndrome type-Ⅰ has not been demonstrated.In the present study,a mouse model of chronic post-ischemia pain was established to mimic complex regional pain syndrome type-Ⅰ and subjected to an intervention involving swimming at different intensities.Chronic pain was reduced only in mice that engaged in high-intensity swimming.The resolvin E1-chemerin receptor 23 axis was clearly downregulated in the spinal cord of mice with chronic pain,while high-intensity swimming restored expression of resolvin E1 and chemerin receptor 23.Finally,shRNA-mediated silencing of chemerin receptor 23in the spinal cord reve rsed the analgesic effect of high-intensity swimming exercise on chronic post-ischemic pain and the anti-inflammato ry pola rization of microglia in the dorsal horn of the spinal cord.These findings suggest that high-intensity swimming can decrease chronic pain via the endogenous resolvin E1-chemerin receptor 23 axis in the spinal cord. 展开更多
关键词 central sensitization chemerin receptor 23 chronic post-ischemia pain complex regional pain syndrome exercise-induced analgesia microglia NEUROINFLAMMATION resolvin E1 spinal cord SWIMMING
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Design and Robustness Analysis of a Wave-Based Controller for Tethered Towing of Defunct Satellites 被引量:1
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作者 Rui Qi Yang Zhang Krishna D.Kumar 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第1期278-280,共3页
Dear Editor, A microgravity environment in space, the elasticity of the tether,and complex flexible appendages make the tethered-towing system a nonlinear and underactuated system, which is sensitive and difficult to ... Dear Editor, A microgravity environment in space, the elasticity of the tether,and complex flexible appendages make the tethered-towing system a nonlinear and underactuated system, which is sensitive and difficult to stabilize. This letter develops a controller based on wave propagation for tethered towing of defunct satellites, and carries out a robustness analysis of the controller via numerical simulation. 展开更多
关键词 system ELASTICITY LETTER
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