目的:调查引导式教育训练对视力障碍学生生活质量的影响。方法:前瞻性随机对照临床研究。选取2020年在泉州特殊教育学校就读视力障碍学生,按照入组条件随机分为引导式教育训练组和对照组,引导式教育训练组进行引导式教育训练,对照组进...目的:调查引导式教育训练对视力障碍学生生活质量的影响。方法:前瞻性随机对照临床研究。选取2020年在泉州特殊教育学校就读视力障碍学生,按照入组条件随机分为引导式教育训练组和对照组,引导式教育训练组进行引导式教育训练,对照组进行常规康复训练。采用中文版低视力者生活质量量表(Chinese-version low vision quality of life questionnaire,CLVQOL)评估视力障碍学生的基线和训练3个月的生活质量,并进行比较分析。结果:72例视力障碍学生全部完成了基线和随访时的生活质量问卷调查。进行基线检查时,各组CLVQOL评分总分差异无统计学意义(P>0.05)。3个月后,各组CLVQOL评分总分均增加,引导式教育训练组从基线59(48.5,80.5)上升到105(97.5,119.5),差异有统计学意义(Z=−4.781,P<0.001);对照组从基线69(56,85)上升到106(80,112),差异有统计学意义(Z=−4.438,P<0.001);引导式教育训练组在CLVQOL评分总分(P=0.021)及阅读和精细工作维度(P=0.004)、日常生活能力维度(P=0.003)的评分差值均高于对照组。结论:引导式教育训练是一种重要的低视力康复训练方法,可以明显提高患者的生活质量。展开更多
Purpose: To observe the clinical effect of alomide and sodium cromoglycate eyedrops in the treatment of atopic conjunctivitis, vernal conjunctivitis and giant papillary conjunctivitis.Methods: Randomized control study...Purpose: To observe the clinical effect of alomide and sodium cromoglycate eyedrops in the treatment of atopic conjunctivitis, vernal conjunctivitis and giant papillary conjunctivitis.Methods: Randomized control study was used. Alomide and sodium cromoglycate eyedrops used to treat two groups of patients for two weeks. The effects of the two groups were compared.Results: With respect of comprehensive therapeutic effect, the effectiveness rate was 83. 6% in alomide group, and 63. 3% in sodium cromoglycate group, which was not significantly different statistically. With respect of itching alleviation, alomide is more effective than sodium cromoglycate. No adverse effects were found in both groups. Conclusion: Our study suggests that alomide is a safe and effective drug in the treatment of allergic conjunctivitis. Eye Science 2000; 16: 214-216.展开更多
Purpose: To select effective drugs against cellular proliferation in the vitreous. Methods: Cyclosporin A (0. 125mg/l - 4.0mg/l) was added to cultures of human retinal pigment epithelial (RPE) cells with or without ma...Purpose: To select effective drugs against cellular proliferation in the vitreous. Methods: Cyclosporin A (0. 125mg/l - 4.0mg/l) was added to cultures of human retinal pigment epithelial (RPE) cells with or without macrophage - conditioned medium (MCM) . Proliferation rate of the cells was measured with (3H) - thymidine incorporation and liquid scintillation techniques on days 3 and 5.Results: Cyclosporin A at a dosages of 0. 125mg/l had a slight inhibition on human RPE cells proliferation (-3.8%-4.1%, P>0.05).Cyclosporin A at a dose ranging from 0.25mg/l to 4.0mg/l inhibited cellular proliferation effectively and in a dose - dependent manner (8.7% -95.1%, P<0.05 r=0.94, P<0.001) with its ID50 of 1.49mg/l. In the culture of RPE with MCM, the inhibition on day 5 was more effective than that on day 3. Conclusion : Cyclosporin A had an effective inhibition on human RPE cell proliferation and it may be of potential use clinically. Eye science 1998; 14 : 41 - 44.展开更多
Tremendous progress is made in recent time in the field of Ophthalmology especially after advent of IOL implantation surgery. Recent advance in anaesthesia/lOL, designs/IOL, quotings/cantering, techniques/advances in ...Tremendous progress is made in recent time in the field of Ophthalmology especially after advent of IOL implantation surgery. Recent advance in anaesthesia/lOL, designs/IOL, quotings/cantering, techniques/advances in operating microscope and advances in suture materials/needles etc. will be discussed.展开更多
文摘目的:调查引导式教育训练对视力障碍学生生活质量的影响。方法:前瞻性随机对照临床研究。选取2020年在泉州特殊教育学校就读视力障碍学生,按照入组条件随机分为引导式教育训练组和对照组,引导式教育训练组进行引导式教育训练,对照组进行常规康复训练。采用中文版低视力者生活质量量表(Chinese-version low vision quality of life questionnaire,CLVQOL)评估视力障碍学生的基线和训练3个月的生活质量,并进行比较分析。结果:72例视力障碍学生全部完成了基线和随访时的生活质量问卷调查。进行基线检查时,各组CLVQOL评分总分差异无统计学意义(P>0.05)。3个月后,各组CLVQOL评分总分均增加,引导式教育训练组从基线59(48.5,80.5)上升到105(97.5,119.5),差异有统计学意义(Z=−4.781,P<0.001);对照组从基线69(56,85)上升到106(80,112),差异有统计学意义(Z=−4.438,P<0.001);引导式教育训练组在CLVQOL评分总分(P=0.021)及阅读和精细工作维度(P=0.004)、日常生活能力维度(P=0.003)的评分差值均高于对照组。结论:引导式教育训练是一种重要的低视力康复训练方法,可以明显提高患者的生活质量。
文摘Purpose: To observe the clinical effect of alomide and sodium cromoglycate eyedrops in the treatment of atopic conjunctivitis, vernal conjunctivitis and giant papillary conjunctivitis.Methods: Randomized control study was used. Alomide and sodium cromoglycate eyedrops used to treat two groups of patients for two weeks. The effects of the two groups were compared.Results: With respect of comprehensive therapeutic effect, the effectiveness rate was 83. 6% in alomide group, and 63. 3% in sodium cromoglycate group, which was not significantly different statistically. With respect of itching alleviation, alomide is more effective than sodium cromoglycate. No adverse effects were found in both groups. Conclusion: Our study suggests that alomide is a safe and effective drug in the treatment of allergic conjunctivitis. Eye Science 2000; 16: 214-216.
基金The project was supported by the national natural science foundation of China (No.39470742)
文摘Purpose: To select effective drugs against cellular proliferation in the vitreous. Methods: Cyclosporin A (0. 125mg/l - 4.0mg/l) was added to cultures of human retinal pigment epithelial (RPE) cells with or without macrophage - conditioned medium (MCM) . Proliferation rate of the cells was measured with (3H) - thymidine incorporation and liquid scintillation techniques on days 3 and 5.Results: Cyclosporin A at a dosages of 0. 125mg/l had a slight inhibition on human RPE cells proliferation (-3.8%-4.1%, P>0.05).Cyclosporin A at a dose ranging from 0.25mg/l to 4.0mg/l inhibited cellular proliferation effectively and in a dose - dependent manner (8.7% -95.1%, P<0.05 r=0.94, P<0.001) with its ID50 of 1.49mg/l. In the culture of RPE with MCM, the inhibition on day 5 was more effective than that on day 3. Conclusion : Cyclosporin A had an effective inhibition on human RPE cell proliferation and it may be of potential use clinically. Eye science 1998; 14 : 41 - 44.
文摘Tremendous progress is made in recent time in the field of Ophthalmology especially after advent of IOL implantation surgery. Recent advance in anaesthesia/lOL, designs/IOL, quotings/cantering, techniques/advances in operating microscope and advances in suture materials/needles etc. will be discussed.